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29321por Mandi, Henshaw, Epie, Bekolo Cavin, Eyoh, Agnes, Jan, Sindhiya, Clemens, Sue Ann Costa, Clemens, Ralf, Yimer, Solomon“…Children who were clinically diagnosed to be concomitantly infected with malaria had a lower risk of RSV infection (odds ratio: 0.38 (0.14, 0.95; P = 0.03). …”
Publicado 2021
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29322por Muhammad, Yahaya, Kani, Yamuna Aminu, Iliya, Sani, Muhammad, Jafaru Bunza, Binji, Abubakar, El-Fulaty Ahmad, Abdurrahman, Kabir, Muhd Bashir, Umar Bindawa, Kabir, Ahmed, Armaya’u“…Furthermore, COVID-19 infection with other comorbidities, such as malaria, hypertension and diabetes, are at higher risk of developing oxidative stress.…”
Publicado 2021
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29323por Zoleko-Manego, Rella, Mischlinger, Johannes, Dejon-Agobé, Jean Claude, Basra, Arti, Mackanga, J. Rodolphe, Akerey Diop, Daisy, Adegnika, Ayola Akim, Agnandji, Selidji T., Lell, Bertrand, Kremsner, Peter G., Matsiegui, Pierre Blaise, González, Raquel, Menendez, Clara, Ramharter, Michael, Mombo-Ngoma, Ghyslain“…This study evaluates growth, nutritional status and mortality of infants from Lambaréné and Fougamou in Gabon from a birth cohort of a malaria in pregnancy clinical trial (NCT00811421). …”
Publicado 2021
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29324por Chen, Yizhe, Zhu, Fangyi, Hammill, Jared, Holbrook, Gloria, Yang, Lei, Freeman, Burgess, White, Karen L., Shackleford, David M., O’Loughlin, Kathleen G., Charman, Susan A., Mirsalis, Jon C., Guy, R. Kiplin“…BACKGROUND: The ongoing global malaria eradication campaign requires development of potent, safe, and cost-effective drugs lacking cross-resistance with existing chemotherapies. …”
Publicado 2021
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29325por Teyssier, Noam B., Chen, Anna, Duarte, Elias M., Sit, Rene, Greenhouse, Bryan, Tessema, Sofonias K.“…BACKGROUND: Whole-genome sequencing (WGS) is becoming increasingly useful to study the biology, epidemiology, and ecology of malaria parasites. Despite ease of sampling, DNA extracted from dried blood spots (DBS) has a high ratio of human DNA compared to parasite DNA, which poses a challenge for downstream genetic analyses. …”
Publicado 2021
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29326“…METHODS: A total sample of 1404 women of reproductive age who had given birth after eight or more ANC contacts had been initiated, taking into account 9 months of gestation, was studied. The Ghana Malaria Indicator Survey of 2019 (GMIS) was used. …”
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29327por Delaunois, Annie, Abernathy, Matthew, Anderson, Warren D., Beattie, Kylie A., Chaudhary, Khuram W., Coulot, Julie, Gryshkova, Vitalina, Hebeisen, Simon, Holbrook, Mark, Kramer, James, Kuryshev, Yuri, Leishman, Derek, Lushbough, Isabel, Passini, Elisa, Redfern, Will S., Rodriguez, Blanca, Rossman, Eric I., Trovato, Cristian, Wu, Caiyun, Valentin, Jean‐Pierre“…In conclusion, our integrated nonclinical CiPA dataset confirmed that, at therapeutic plasma concentrations relevant for malaria or off‐label use in COVID‐19, CLQ and OH‐CLQ use is associated with a proarrhythmia risk, which is higher in populations carrying predisposing factors but not worsened with macrolide combination.…”
Publicado 2021
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29328por Mbiya, Benoît Mukinayi, Kalombo, Didier Kalenda, Mukendi, Yannick Nkesu, Daubie, Valery, Mpoyi, John Kalenda, Biboyi, Parola Mukendi, Disashi, Ghislain Tumba, Gulbis, Béatrice“…METHOD: A cohort of 143 children with SCD aged 10 years old (IQR (interquartile range): 6–15 years) (sex ratio male/female = 1.3) were clinically followed for 12 months without any specific intervention aside from the management of acute events, and then for 12 months with a monthly medical visit, biological follow-up, and chemoprophylaxis (folic acid/penicillin), adequate fluids and malaria prevention. RESULTS: The median age of patients at the diagnosis of SCD was 2 years (IQR: 1–5). …”
Publicado 2021
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29329“…METHODS: Two hundred and forty-nine samples were collected from patients with microscopy confirmed P. falciparum malaria attending Aga Khan University Hospital during September 2015-April 2018. …”
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29330por Munywoki, Daniel N., Kokwaro, Elizabeth D., Mwangangi, Joseph M., Muturi, Ephantus J., Mbogo, Charles M.“…BACKGROUND: The rapid and widespread evolution of insecticide resistance has emerged as one of the major challenges facing malaria control programs in sub-Saharan Africa. Understanding the insecticide resistance status of mosquito populations and the underlying mechanisms of insecticide resistance can inform the development of effective and site-specific strategies for resistance prevention and management. …”
Publicado 2021
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29331por Mapoma, C. Chabila, Munkombwe, Brian, Mwango, Chomba, Bwalya, Bupe Bwalya, Kalindi, Audrey, Gona, N. Philimon“…RESULTS: Opportunistic infections (OIs) associated with HIV/AIDS such as pneumonia and tuberculosis, and malaria were among leading causes of deaths among bodies “brought-in-dead”. …”
Publicado 2021
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29332por Das, Sabyasachi, Kar, Amrita, Manna, Subhankar, Mandal, Samaresh, Mandal, Sayantani, Das, Subhasis, Saha, Bhaskar, Hati, Amiya Kumar“…Emergence and spread of resistant parasite in eastern-India poses a threat to national malaria control programs. Therefore, the objective of our study is to evaluate the artesunate-sulfadoxine-pyrimethamine efficacy in Central India. 180 monoclonal P. falciparum-infected patients received standard ASSP therapy during August 2015–January 2017, soon after diagnosis and monitored over next 42-days. …”
Publicado 2021
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29333por Coker, Modupe, Folayan, Morenike O., Michelow, Ian C., Oladokun, Regina E., Torbunde, Nguavese, Sam-Agudu, Nadia A.“…Of particular concern are programs targeting major conditions among children, such as undernutrition, vaccine-preventable pneumonia and diarrhea, malaria, tuberculosis, HIV, and sickle cell disease. …”
Publicado 2020
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29334“…Several anti-malarial drugs have been evaluated in randomized clinical trials to treat acute uncomplicated Plasmodium falciparum malaria. The outcome of anti-malarial drug efficacy studies is classified into one of four possible outcomes defined by the World Health Organization: adequate clinical and parasitological response, late parasitological failure, late clinical failure, early treatment failure. …”
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29335por Negatou, Mariamawit, Ouedraogo, Mady, Donnen, Philippe, Paul, Elisabeth, Samadoulougou, Sekou, Kirakoya-Samadoulougou, Fati“…Caregivers who did not have messages regarding malaria in the past six months were more likely not to seek care (PR = 0.8 (95% CI, 0.7–0.9)). …”
Publicado 2021
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29336por Pokhrel, Anil, Rayamajhee, Binod, Khadka, Saroj, Thapa, Sandeep, Kapali, Samjhana, Pun, Sher Bahadur, Banjara, Megha Raj, Joshi, Prakash, Lekhak, Binod, Rijal, Komal Raj“…Data generated were analyzed using SPSS software version 24.0. (3) Results: Amongst the 2070 febrile patients, 462 (22.3%) were seropositive to at least one etiological agent of febrile illnesses (scrub typhus: 253 cases, dengue: 101 cases, leptospirosis: 9, brucellosis: 52, malaria: 9 and kala-azar: 20 cases). Scrub typhus accounted for 12.2% (n = 253) of total febrile illnesses followed by dengue (4.9%, n = 101). …”
Publicado 2021
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29337“…A total of 1 653 mothers of under 5 years who had an episode of diarrhoea, malaria, pneumonia or a combination of any of them not more than 14 days before the interview were included in the study. …”
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29338“…The recent decline in disease burden in sub-Saharan Africa is disproportionally driven by improvements in DALY rates for HIV/AIDS, as well as for malaria, diarrheal diseases, and lower respiratory infections.…”
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29339por Winskill, Peter, Hogan, Alexandra B., Thwing, Julie, Mwandigha, Lazaro, Walker, Patrick G. T., Lambert, Ben“…BACKGROUND: Pneumonia, diarrhoea and malaria are responsible for over one third of all deaths in children under the age of 5 years in low and middle sociodemographic index countries; many of these deaths are also associated with malnutrition. …”
Publicado 2021
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29340por Sinha, Shweta, Prakash, Ajay, Medhi, Bikash, Sehgal, Alka, Batovska, Daniela I., Sehgal, Rakesh“…OBJECTIVE: Malaria is a major global health concern with the urgent need for new treatment alternatives due to the alarming increase of drug-resistant Plasmodium strains. …”
Publicado 2021
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