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29501por Schwenk, Robert, DeBot, Margot, Porter, Michael, Nikki, Jennifer, Rein, Lisa, Spaccapelo, Roberta, Crisanti, Andrea, Wightman, Paul D., Ockenhouse, Christian F., Dutta, Sheetij“…The availability of a highly purified and well characterized circumsporozoite protein (CSP) is essential to improve upon the partial success of recombinant CSP-based malaria vaccine candidates. Soluble, near full-length, Plasmodium falciparum CSP vaccine antigen (CS/D) was produced in E. coli under bio-production conditions that comply with current Good Manufacturing Practices (cGMP). …”
Publicado 2014
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29502por Rugera, Simon Peter, McNerney, Ruth, Poon, Albert K, Akimana, Gladys, Mariki, Rehema Forgen, Kajumbula, Henry, Kamau, Elizabeth, Mpawenimana, Servilien, Said, Said Yusuf, Toroitich, Anthony, Ronoh, Wesley, Sollis, Kimberly A, Sonoiya, Stanley, Peeling, Rosanna W“…RESULTS: Control of medical devices and IVDs in EAC Partner States is largely confined to national disease programmes such as tuberculosis, HIV and malaria. National Regulatory Authorities for pharmaceutical products do not have the capacity to regulate medical devices and in some countries laboratory based organisations are mandated to ensure quality of products used. …”
Publicado 2014
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29503por Ricotta, Emily E, Boulay, Marc, Ainslie, Robert, Babalola, Stella, Fotheringham, Megan, Koenker, Hannah, Lynch, Matthew“…This study introduces ideation theory and mediation analysis as a way to evaluate the impact of a malaria SBCC campaign in Tanzania, to determine whether exposure to a communication programme influenced universal coverage through mediating ideational variables. …”
Publicado 2015
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29504por Lu, Gang, Zhou, Aihua, Meng, Min, Wang, Lin, Han, Yali, Guo, Jingjing, Zhou, Huaiyu, Cong, Hua, Zhao, Qunli, Zhu, Xing-Quan, He, Shenyi“…In addition, alpha-Galactosylceramide (α-GalCer) was used to be an adjuvant in malaria vaccine and received positive results. In this study, the effect of the DNA vaccine enhanced by α-GalCer was evaluated by immunizing BALB/c mice. …”
Publicado 2014
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29505por Hoogenboom, Gabie, Thwin, May Myo, Velink, Kris, Baaijens, Marijke, Charrunwatthana, Prakaykaew, Nosten, François, McGready, Rose“…METHODS: In the obstetric department of Shoklo Malaria Research Unit (SMRU) the standardized WHO Safe Motherhood Needs Assessment tool was adapted to the setting and used: to assess the facility; interview SBAs; collect data from maternal records during a one year period (August 2007 – 2008); and observe practice during labour and childbirth. …”
Publicado 2015
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29506por Boettcher, Jan P, Siwakoti, Yubaraj, Milojkovic, Ana, Siddiqui, Niyamat A, Gurung, Chitra K, Rijal, Suman, Das, Pradeep, Kroeger, Axel, Banjara, Megha R“…In Bihar it was 28 days for “District Malaria Offices”. In Nepal, 73% of health managers entered data into computers compared to 16% in Bihar. …”
Publicado 2015
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29507por Kaushik, Naveen K, Bagavan, Asokan, Rahuman, Abdul A, Zahir, Abdul A, Kamaraj, Chinnaperumal, Elango, Gandhi, Jayaseelan, Chidambaram, Kirthi, Arivarasan V, Santhoshkumar, Thirunavukkarasu, Marimuthu, Sampath, Rajakumar, Govindasamy, Tiwari, Santosh K, Sahal, Dinkar“…CONCLUSION: These results provide validity to the traditional medicinal usage of some of these plants and further make a case for activity-guided purification of new pharmacophores against malaria. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12936-015-0564-z) contains supplementary material, which is available to authorized users.…”
Publicado 2015
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29508por Burger, Pieter B, Williams, Marni, Sprenger, Janina, Reeksting, Shaun B, Botha, Mariëtte, Müller, Ingrid B, Joubert, Fourie, Birkholtz, Lyn-Marie, Louw, Abraham I“…BACKGROUND: Plasmodium falciparum is the most pathogenic of the human malaria parasite species and a major cause of death in Africa. …”
Publicado 2015
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29509por Zhang, Hong-wei, Liu, Ying, Hu, Tao, Zhou, Rui-min, Chen, Jian-she, Qian, Dan, Yang, Cheng-yun, Zhao, Yu-ling, Li, Su-hua, Cui, Jing, Wang, Zhong-quan, Feng, Zhanchun, Xu, Bian-li“…BACKGROUND: Vivax malaria was historically epidemic in Henan Province of China and Anopheles sinensis was the main vectors and poor farming communities bare the greatest burden of disease. …”
Publicado 2015
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29510“…BACKGROUND: Members of the Anopheles gambiae complex are the main transmitters of malaria. Anopheles merus is a member of the complex found along the Kenyan coast because it breeds in saline waters. …”
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29511por Nakimuli, Annettee, Mbalinda, Scovia N, Nabirye, Rose C, Kakaire, Othman, Nakubulwa, Sarah, Osinde, Michael O, Kakande, Nelson, Kaye, Dan K“…The obstetric conditions included obstetric haemorrhage, hypertensive disorders, obstructed labour, chorioamnionitis and pregnancy-specific complications such as malaria, anemia and premature rupture of membranes. …”
Publicado 2015
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29512por Galinsky, Kevin, Valim, Clarissa, Salmier, Arielle, de Thoisy, Benoit, Musset, Lise, Legrand, Eric, Faust, Aubrey, Baniecki, Mary Lynn, Ndiaye, Daouda, Daniels, Rachel F, Hartl, Daniel L, Sabeti, Pardis C, Wirth, Dyann F, Volkman, Sarah K, Neafsey, Daniel E“…BACKGROUND: Complex malaria infections are defined as those containing more than one genetically distinct lineage of Plasmodium parasite. …”
Publicado 2015
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29513por Mazigo, Humphrey D, Dunne, David W, Morona, Domenica, Lutufyo, Therese E, Kinung’hi, Safari M, Kaatano, Geofrey, Nuwaha, Fred“…Predictors of the height-adjusted measurements of the left liver lobe and spleen were age, male gender, malaria infection, fishing occupation, village of residence and heavy intensity of S. mansoni infection. …”
Publicado 2015
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29514por Prakash, Jai, Singh, Takhellambam Brojen, Ghosh, Biplab, Malhotra, Vinay, Rathore, Surendra Singh, Vohra, Rubina, Mishra, Rabindra Nath, Srivastava, Pramod Kumar, Usha“…Incidences of obstetrical, surgical and diarrheal AKI have decreased significantly, whereas those of AKI associated with malaria, sepsis, nephrotoxic drugs and liver disease have increased. …”
Publicado 2013
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29515“…BACKGROUND: The doublesex gene controls somatic sexual differentiation of many metazoan species, including the malaria mosquito Anopheles gambiae and the dengue and yellow fever vector Aedes aegypti (Diptera: Culicidae). …”
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29516por Tungu, Patrick K., Malima, Robert, Mosha, Frank W., Lyimo, Issa, Maxwell, Caroline, Kaur, Harparkash, Kisinza, William N., Magesa, Stephen M., Kirby, Matthew J., Rowland, Mark“…BACKGROUND: Insecticide-treated nets are the primary method of preventing malaria. To remain effective, the pyrethroid insecticide must withstand multiple washes over the lifetime of the net. …”
Publicado 2015
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29517por de Souza, Aracele M., de Araújo, Flávia C. F., Fontes, Cor J. F., Carvalho, Luzia H., de Brito, Cristiana F. A., de Sousa, Taís N.“…Characterizing the multiplicity of infection has broad implications that range from population genetic studies of the parasite to malaria treatment and control. This study compared and evaluated the efficiency of neutral and non-neutral markers that are widely used in studies of molecular epidemiology to detect the multiplicity of P. vivax infection. …”
Publicado 2015
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29518por Yin, Weiwei, Garimalla, Swetha, Moreno, Alberto, Galinski, Mary R., Styczynski, Mark P.“…Finally, we demonstrate the utility of this approach via the analysis of a transcriptional dataset of a malaria challenge in a non-human primate model system, Macaca mulatta, suggesting the potential to capture indicators of the earliest stages of cellular differentiation during leukopoiesis. …”
Publicado 2015
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29519por Wollum, Alexandra, Burstein, Roy, Fullman, Nancy, Dwyer-Lindgren, Laura, Gakidou, Emmanuela“…RESULTS: Under-5 mortality decreased in all states from 2000 to 2013, but a large gap remained across them. Malaria intervention coverage stayed low despite increases between 2009 and 2013, largely driven by rising rates of insecticide-treated net ownership. …”
Publicado 2015
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29520por Bonizzoni, Mariangela, Ochomo, Eric, Dunn, William Augustine, Britton, Monica, Afrane, Yaw, Zhou, Guofa, Hartsel, Joshua, Lee, Ming-Chieh, Xu, Jiabao, Githeko, Andrew, Fass, Joseph, Yan, Guiyun“…BACKGROUND: The extensive use of pyrethroids for control of malaria vectors, driven by their cost, efficacy and safety, has led to widespread resistance. …”
Publicado 2015
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