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  1. 29661
    “…Venous blood was obtained for estimation of creatinine level and for malaria diagnosis. The primary outcomes were the prevalence of renal abnormalities, defined by the presence of low estimated glomerular filtration rate (eGFR), proteinuria or microalbuminuria, and hematuria in urine. …”
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    Renal abnormalities and its associated factors among school-aged children living in Schistosoma mansoni endemic communities in Northwestern Tanzania
  2. 29662
    “…Their use has substantial potential to contribute to a greater understanding of the bio-ecology of this important malaria vector. Rhodamine B has the advantage that it appears to be permanent and is less easily confused with auto-fluorescence. …”
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    Fluorescent markers rhodamine B and uranine for Anopheles gambiae adults and matings
  3. 29663
    “…Chloroquine (CQ) and hydroxychloroquine (HCQ) are typically used in the treatment of rheumatoid arthritis, systemic lupus erythematosus and malaria; they have been considered for off-label and compassionate use in several countries against moderate to severe cases of COVID-19 and there's actually a massive demand of these two drugs. …”
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    Chloroquine and hydroxychloroquine ototoxicity; potential implications for SARS-CoV-2 treatment. A brief review of the literature
  4. 29664
    “…This study investigated the host and parasite genetic factors affecting the susceptibility of the malaria parasite to ACT partner drugs. METHODS: Archived samples from 240 patients age ≤ 9 years participating in anti-malarial drug resistance survey in Ghana, and given artemether with lumefantrine (AL) or artesunate with amodiaquine (AA), were selected and analysed. …”
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    Plasmodium falciparum genetic factors rather than host factors are likely to drive resistance to ACT in Ghana
  5. 29665
    “…BACKGROUND: The emergence of artemisinin-resistant malaria parasites highlights the need for novel drugs and their targets. …”
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    Molecular characterization of Plasmodium falciparum DNA-3-methyladenine glycosylase
  6. 29666
    “…BACKGROUND: Artesunate plus sulfadoxine–pyrimethamine (ASP) is first-line treatment for uncomplicated Plasmodium falciparum malaria in most of India, except for six North-eastern provinces where treatment failure rates were high. …”
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    Stable high frequencies of sulfadoxine–pyrimethamine resistance associated mutations and absence of K13 mutations in Plasmodium falciparum 3 and 4 years after the introduction of artesunate plus sulfadoxine–pyrimethamine in Ujjain, Madhya Pradesh, India
  7. 29667
    “…BACKGROUND: Despite noticeable improvement in anti-malarial treatment, rapid growth of resistant malaria strains points out the need for continuous development of novel anti-malarials to fight the disastrous infection. …”
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    Correlation between anti-malarial and anti-haemozoin activities of anti-malarial compounds
  8. 29668
    “…Overall, the majority of the studies identified were from Sub-Saharan Africa and were published within the last 5 years. Malaria and maternal health were the most commonly studied health conditions, although a number of other health conditions and health services were also explored. …”
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    Using routine health information data for research in low- and middle-income countries: a systematic review
  9. 29669
    “…BACKGROUND: The intra-erythrocytic development of the malaria parasite Plasmodium falciparum depends on the uptake of a number of essential nutrients from the host cell and blood plasma. …”
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    Human plasma plasminogen internalization route in Plasmodium falciparum-infected erythrocytes
  10. 29670
    “…While these odour sources are normally spatio-temporally segregated in a mosquito’s life history, here this study explored to what extent a combination of flower- and human-mimicking synthetic volatiles would attract the malaria vector Anopheles gambiae sensu stricto (s.s.) …”
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    Is Anopheles gambiae attraction to floral and human skin-based odours and their combination modulated by previous blood meal experience?
  11. 29671
    por Zhang, Yumin, Li, Wei, Zhou, Yunting
    Publicado 2020
    “…Enriched pathways of the upregulated DEGs included extracellular matrix (ECM) receptor interaction, focal adhesion, human papillomavirus infection, malaria, and cell adhesion molecules. The downregulated DEGs were mainly enriched in ascorbate and aldarate metabolism, arginine and proline metabolism, endocrine- and other factor-regulated calcium reabsorption, mineral absorption and longevity regulating pathway, and multiple species signaling pathway. …”
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    Identification of hub genes in diabetic kidney disease via multiple-microarray analysis
  12. 29672
    “…We updated the MHFL and assessed service delivery parameters in the Malaria Frontline Project implementing areas in Kano and Zamfara States. …”
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    Assessment of health service delivery parameters in Kano and Zamfara States, Nigeria
  13. 29673
    “…Independent predictors of time to recovery were play stimulation (AHR=1.93, 95% CI: 1.23–3.03), vaccination status (AHR=2.26, 95% CI: 1.12–4.57), tuberculosis (AHR= 0.48, 95% CI: 0.27–0.87), malaria (AHR=0.34,95% CI:0.13–0.88), use of amoxicillin (AHR=1.54, 95% CI: 0.008–2.34), deworming (AHR=1.8, 95% CI: 1.18–2.73), and shock (AHR=0.18, 95% CI: 0.05–0.59). …”
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    Time to Cure and Predictors of Recovery Among Children Aged 6–59 Months with Severe Acute Malnutrition Admitted in Jimma University Medical Center, Southwest Ethiopia: A Retrospective Cohort Study
  14. 29674
    “…BACKGROUND: The malaria parasite Plasmodium falciparum has an unusually euchromatic genome with poorly conserved positioning of nucleosomes in intergenic sequences and poorly understood mechanisms of gene regulation. …”
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    Histone modifications associated with gene expression and genome accessibility are dynamically enriched at Plasmodium falciparum regulatory sequences
  15. 29675
    “…Malaria remains a major healthcare risk to growing economies like India, and a chromosome-level reference genome of Anopheles stephensi is critical for successful vector management and understanding of vector evolution using comparative genomics. …”
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    A Near-Chromosome Level Genome Assembly of Anopheles stephensi
  16. 29676
    “…The present study was designed and performed to provide genetic epidemiological data of the prevalence of N86Y-Y184F-D1246Y SNPs in Plasmodium falciparum multidrug resistance 1 (pfmdr1) in the malaria hotspot of Northern Nigeria. METHODS: Plasmodium falciparum-positive blood samples on Whatman-3MM filter papers were collected from 750 symptomatic patients from four states (Kano, Kaduna, Yobe and Adamawa) in Northern Nigeria, and genotyped via BigDye (v3.1) terminator cycle sequencing for the presence of three SNPs in pfmdr1. …”
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    Plasmodium falciparum multidrug resistance gene-1 polymorphisms in Northern Nigeria: implications for the continued use of artemether-lumefantrine in the region
  17. 29677
    “…We have previously repurposed pyronaridine, tilorone and quinacrine (from malaria, influenza, and antiprotozoal uses, respectively) as inhibitors of Ebola and Marburg virus in vitro in HeLa cells and of mouse adapted Ebola virus in mouse in vivo. …”
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    Repurposing the Ebola and Marburg Virus Inhibitors Tilorone, Quinacrine and Pyronaridine: In vitro Activity Against SARS-CoV-2 and Potential Mechanisms
  18. 29678
    “…Dihydroartemisinin (DHA), the main active metabolite of artemisinin derivatives, is a well-known drug for the treatment of malaria. Previous studies have demonstrated that DHA exhibits antitumor effects toward a variety of human cancers and has a potential for repurposing as an anticancer drug. …”
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    Evaluation of the Anticancer Activity of a Bile Acid-Dihydroartemisinin Hybrid Ursodeoxycholic-Dihydroartemisinin in Hepatocellular Carcinoma Cells
  19. 29679
    “…These findings are important as they show the potential for DL-methionine and the combination of DL-methionine with BTI to be used as a larvicide against Anopheles mosquitoes, which are responsible for transmitting malaria. ABSTRACT: Mosquito larvicides can reduce mosquito populations at the source, potentially decreasing biting rates and pathogen transmission. …”
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    Combining DL-Methionine and Bacillus thuringiensis Subspecies israelensis: Prospects for a Mosquito Larvicide
  20. 29680
    “…Younger travelers were more likely engage in risk behaviors (e.g. consume poorly cooked meat or seafood (16% vs 9%) or street vendor food (26% vs 8.6%), wade in fresh water (24% vs. 18%), and non-compliance with malaria prophylaxis (22% vs 12%) (p< 0.05). Older travelers had a lower incidence of TD (18% vs 24%), and a higher proportion of cases with loose stool or mild TD that did not interfere with daily activities (63% vs. 51%) (p< 0.05). …”
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    207. Travel Related Risk Behaviors and Antibiotic Use among Older Travelers
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