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29721por Perry, Henry B., Chowdhury, Mushtaque, Were, Miriam, LeBan, Karen, Crigler, Lauren, Lewin, Simon, Musoke, David, Kok, Maryse, Scott, Kerry, Ballard, Madeleine, Hodgins, Steve“…These goals include achieving the health-related Sustainable Development Goals of Universal Health Coverage, ending preventable child and maternal deaths, and making a major contribution to the control of HIV, tuberculosis, malaria, and noncommunicable diseases. CHWs can also play a critical role in responding to current and future pandemics. …”
Publicado 2021
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29722“…This medicinal plant is effective against multiple pathogens and is used by many global communities as a source of artemisinin derivatives that are first-line drugs to treat malaria caused by Plasmodium parasites. AIM OF THE STUDY: The SARS-CoV-2 (Covid-19) global pandemic has killed millions and evolved numerous variants, with delta being the most transmissible to date and causing break-through infections of vaccinated individuals. …”
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29723por Amornchai, Premjit, Hantrakun, Viriya, Wongsuvan, Gumphol, Wuthiekanun, Vanaporn, Wongratanacheewin, Surasakdi, Teparrakkul, Prapit, West, T. Eoin, AuCoin, David P., Day, Nicholas P. J., Brett, Paul J., Burtnick, Mary N., Chantratitra, Narisara, Limmathurotsakul, Direk“…Controls included 502 patients who were blood culture positive for Staphylococcus aureus, Escherichia coli or Klebsiella pneumoniae or were polymerase chain reaction assay positive for malaria or dengue. Serum samples collected within 24 hours of admission were stored and tested using a CPS-LFI, Hcp1-ELISA and OPS-ELISA. …”
Publicado 2021
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29724“…Wood is widely used in South Africa and some other African countries for treatment of various infectious diseases such as diarrhea, fevers, cancer, diabetes and malaria. However, little is known about the active constituents associated with the biological activities. …”
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29725por da Cruz, Derciliano Lopes, Paiva, Marcelo Henrique Santos, Guedes, Duschinka Ribeiro Duarte, de Souza Gomes, Elainne Christine, Pires, Silvia Gonçalves, Gomez, Lara Ferrero, Ayres, Constância Flávia Junqueira“…BACKGROUND: Due to the lack of vaccines, malaria control mainly involves the control of anopheline vectors (Anopheles spp.) using chemical insecticides. …”
Publicado 2021
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29726por Ciccone, Emily J., Kabugho, Lydia, Baguma, Emmanuel, Muhindo, Rabbison, Juliano, Jonathan J., Mulogo, Edgar, Boyce, Ross M.“…To evaluate the preliminary feasibility and potential impact of adding pathogen-specific and clinical biomarker diagnostic testing to existing clinical management algorithms, we conducted a prospective, observational cohort study of 225 children presenting with malaria-negative, febrile ARI to the outpatient department of a semi-urban peripheral health facility in southwestern Uganda from October 2019 to January 2020. …”
Publicado 2021
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29727por Pickering, Harry, Hart, John D., Burr, Sarah, Stabler, Richard, Maleta, Ken, Kalua, Khumbo, Bailey, Robin L., Holland, Martin J.“…Numerous studies have reported secondary effects of MDA with azithromycin, including reductions in childhood mortality, diarrhoeal disease and malaria. Most recently, the MORDOR clinical trial demonstrated that MDA led to an overall reduction in all-cause childhood mortality in targeted communities. …”
Publicado 2022
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29728“…From China, Tu Youyou is a Nobel laureate who discovered artemisinin and dihydroartemisinin, used to treat malaria, a breakthrough in twentieth-century tropical medicine, saving millions of lives around the globe. …”
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29729por Sweileh, Waleed M.“…The main findings of the study are summarized as follows: (a) COVID-19 had a strong impact on the number of publications in the field, specifically during the years 2020 and 2021; (b) research in the field was published in a wide range of journals, mainly those in the field of infectious diseases and mathematical sciences; (c) research in the field was mainly published by scholars in the United States and the United Kingdom; (d) international research collaboration between active countries and less developed countries was poor; (e) research activity relied on research groups with a large number of researchers per group indicative of good author-author collaboration; (f) HIV/AIDS, coronavirus disease, influenza, and malaria were the most frequently researched diseases; (g) recently published articles on COVID-19 received the highest number of citations; and (h) researchers in the Eastern Mediterranian and South-East Asian regions made the least contribution to the retrieved articles. …”
Publicado 2022
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29730por Ford, Anthony, Kepple, Daniel, Williams, Jonathan, Kolesar, Gabrielle, Ford, Colby T., Abebe, Abnet, Golassa, Lemu, Janies, Daniel A., Yewhalaw, Delenasaw, Lo, Eugenia“…For the transmission of the malaria parasite from infected human to the vector, gametocytes play a major role. …”
Publicado 2022
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29731por SheelaNair, Arya, Romanczuk, Aleksandra S., Aogo, Rosemary A., Haldar, Rohit Nemai, Lansink, Lianne I. M., Cromer, Deborah, Salinas, Yandira G., Guy, R. Kiplin, McCarthy, James S., Davenport, Miles P., Haque, Ashraful, Khoury, David S.“…BACKGROUND: Artemisinin-based combination therapy (ACT) has been a mainstay for malaria prevention and treatment. However, emergence of drug resistance has incentivised development of new drugs. …”
Publicado 2022
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29732por Adegbite, Bayode Romeo, Edoa, Jean Ronald, Schaumburg, Frieder, Alabi, Abraham S., Adegnika, Ayola Akim, Grobusch, Martin P.“…Some HCW (28%; 13/47) reported having prescribed antibiotics because the patients asked for them; and a total of 15/47 (32%) responded that antibiotics could help patients recover faster when added to malaria treatment. Compared to nurses, most of the physicians recognised that excessive use of antibiotics without microbiological confirmation of infection could contribute to AMR spread (18/19 (95%) vs 19/28 (68%); p = 0.028). …”
Publicado 2022
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29733por Tang, Yexiao, Li, Xiaobo, Yuan, Yueming, Zhang, Hongying, Zou, Yuanyuan, Xu, Zhiyong, Xu, Qin, Song, Jianping, Deng, Changsheng, Wang, Qi“…(A. annua) has been traditionally used to control many inflammatory diseases, such as malaria and rheumatoid arthritis. We performed network analysis and employed molecular docking and network analysis to elucidate active components or targets and the underlying mechanisms of A. annua for the treatment of COVID-19. …”
Publicado 2022
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29734por Luo, Jiaer, Mobley, Rebecca, Woodfine, Sian, Drijfhout, Falko, Horrocks, Paul, Ren, Xiao-Dong, Li, Wen-Wu“…ABSTRACT: Artemisinin is a component part of current frontline medicines for the treatment of malaria. The aim of this study is to make analogues of artemisinin using microbial transformation and evaluate their in vitro antimalarial activity. …”
Publicado 2022
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29735por Eze, Michael O., Ejike, Chukwunonso E.C.C., Ifeonu, Patrick, Udeinya, Iroka J., Udenigwe, Chibuike C., Uzoegwu, Peter N.“…In this regard, the acetone-water extract of the leaf of the Neem (Azadirachta indica) plant has been known to prevent the adherence of malaria parasitized red blood cells (pRBCs) to VE; prevent cytoadherence of cancer cells in metastasis; and prevent HIV from invading target T lymphocytes. …”
Publicado 2022
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29736por Miller, James S, Mulogo, Edgar Mugema, Wesuta, Andrew Christopher, Mumbere, Nobert, Mbaju, Jackson, Matte, Michael, Ntaro, Moses, Guiles, Daniel A, Patel, Palka R, Bwambale, Shem, Kenney, Jessica, Reyes, Raquel, Stone, Geren S“…OBJECTIVE: Integrated community case management (iCCM) of childhood illness in Uganda involves protocol-based care of malaria, pneumonia and diarrhoea for children under 5 years old. …”
Publicado 2022
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29737por Cantillon, Daire, Goff, Aaron, Taylor, Stuart, Salehi, Emad, Fidler, Katy, Stoneham, Simon, Waddell, Simon J“…METHODS: In an open drug discovery approach, we screened the Medicines for Malaria Venture (MMV) Pathogen Box to assess the in-vitro antimicrobial drug susceptibility of M chimaera compared with the antimicrobial drug susceptibility of the slowly growing, major human pathogen Mycobacterium tuberculosis, and the rapidly growing Mycobacterium abscessus reference strains. …”
Publicado 2022
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29738por Tamene, Aiggan, Habte, Aklilu, Woldeyohannes, Demelash, Afework, Abel, Endale, Fitsum, Gizachew, Addisalem, Sulamo, Dawit, Tesfaye, Legesse, Tagesse, Mihretu“…BACKGROUND: In terms of global impact, foodborne infections have been likened to major infectious diseases such as HIV/AIDS, malaria, and tuberculosis, with 1 in 10 people becoming ill and 420,000 deaths per year. …”
Publicado 2022
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29739por Lees, Rosemary S., Armistead, Jennifer S., Azizi, Salum, Constant, Edi, Fornadel, Christen, Gimnig, John E., Hemingway, Janet, Impoinvil, Daniel, Irish, Seth R., Kisinza, William, Lissenden, Natalie, Mawejje, Henry D., Messenger, Louisa A., Moore, Sarah, Ngufor, Corine, Oxborough, Richard, Protopopoff, Natacha, Ranson, Hilary, Small, Graham, Wagman, Joseph, Weetman, David, Zohdy, Sarah, Spiers, Angus“…A focus group of experts discussed how this should best be done, considering pros and cons of different approaches, and co-wrote a protocol, which will be valuable for malaria control programmes and stakeholders wanting to test the effective lifespan of a new bed net in terms of the active ingredient bioefficacy. …”
Publicado 2022
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29740por Mank, Isabel, Sorgho, Raissa, Zerbo, Fanta, Kagoné, Moubassira, Coulibaly, Boubacar, Oguso, John, Mbata, Michael, Khagayi, Sammy, Muok, Erick M. O., Sié, Ali, Danquah, Ina“…Secondary outcomes comprise other anthropometric indices, iron and zinc status, dietary behavior, malaria indicators, and household socioeconomic status. …”
Publicado 2022
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