“…A malaria survey was conducted in Atar, the northernmost oasis city in Mauritania, during 2015–2016. …”
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“…BACKGROUND: Transcriptomic research of blood cell lineages supports the understanding of distinct features of the immunopathology in human malaria. METHODS: We used microarray hybridization, validated by real-time RT-PCR to analyze whole blood gene expression in healthy Gabonese children and children with various conditions of Plasmodium falciparum infection, including i) asymptomatic infection, ii) uncomplicated malaria, iii) malaria associated with severe anemia and iv) cerebral malaria. …”
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“…Malaria is a tropical disease secondary to the Plasmodium parasite with clinical features ranging from febrile illness to acute renal failure and further renal sequelae. …”
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“…The Kenyan study also reported a reduction in the incidence of new malaria cases (RR 0.62, 95% CI 0.38 to 1.01; 720 participants; very low‐certainty evidence). …”
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“…Malaria remains a major health problem in Cameroon; It accounts for 38% of consultations, 24% of deaths and 36.8% of absenteeism in the country. …”
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“…Developing efficacious vaccines for human malaria caused by Plasmodium falciparum is a major global health priority, although this has proven to be immensely challenging over the decades. …”
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“…Although various interventions to control malaria have been implemented in Rwanda, the incidence of malaria has increased since 2012. …”
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“…Since then, the beneficial effects of quinine and its more advanced synthetic forms, chloroquine and hydroxychloroquine, have been increasingly recognized in a myriad of other diseases in addition to malaria. In recent years, antimalarials were shown to have various immunomodulatory effects, and currently have an established role in the management of rheumatic diseases, such as systemic lupus erythematosus and rheumatoid arthritis, skin diseases, and in the treatment of chronic Q fever. …”
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“…PURPOSE: Malaria is a life-threatening infectious disease caused by the Plasmodium parasite. …”
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“…Just after World War II, more than 10,000 malaria cases per year were reported in Japan, including indigenous, imported and induced malaria. …”
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“…Within 30 years of Laveran’s discovery of human malaria parasites in 1880, four species, Plasmodium falciparum, P. vivax, P. malar-iae and P. ovale, had been described and their morphological distinguishing features clarified. …”
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“…Much of the gain in malaria control, in terms of regional achievements in restricting geographical spread and reducing malaria cases and deaths, can be attributed to large-scale deployment of antimalarial drugs, insecticide-treated bed nets, and early diagnostics. …”
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“…Around one third of the variability in the risk of severe and complicated malaria is now explained by additive host genetic effects. …”
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“…A promising vaccine fails to provide durable protection against infection and clinical malaria in infants, a key malaria vaccine target population, in a phase 2b clinical trial. …”
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“…Lactic acidosis and hyperlactatemia are common metabolic disturbances in patients with severe malaria. Lactic acidosis causes physiological adverse effects, which can aggravate the outcome of malaria. …”
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