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381por Alshukairi, Abeer N., Khalid, Imran, Ahmed, Waleed A., Dada, Ashraf M., Bayumi, Daniyah T., Malic, Laut S., Althawadi, Sahar, Ignacio, Kim, Alsalmi, Hanadi S., Al-Abdely, Hail M., Wali, Ghassan Y., Qushmaq, Ismael A., Alraddadi, Basem M., Perlman, StanleyEnlace del recurso
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385por Cappuccino, Chiara, Spoletti, Enrico, Renni, Fiammetta, Muntoni, Elisabetta, Keiser, Jennifer, Voinovich, Dario, Perissutti, Beatrice, Lusi, Matteo“…The knowledge of several cocrystals with dicarboxylic acids has prompted the realization of solid solutions of PZQ with both enantiomers of malic acid and tartaric acid. Here, the solid form landscape of such a six-component system has been investigated. …”
Publicado 2023
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386“…Here, we show the role of malic enzyme 2 (ME2) in promoting human liver cancer cell lines SK-Hep1 and Huh7 cells migration and invasion. …”
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387por Aloufi, Bandar, Alshammari, Ahmad Mohajja, Alshammari, Nawaf, Alam, Mohammad Jahoor“…We report the binding features of Ascorbic acid, Cysteine, Dithioerythriol, Dithiothreitol, Malic acid and α-Tocopherol with beta amyloid having binding energy values of -6.7, -6.5, -6.0, -6.5, -6.7 and - 7.0 kcal/mol respectively. …”
Publicado 2022
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388por Fu, Gongyu, Li, Shi-Ting, Jiang, Zetan, Mao, Qiankun, Xiong, Nanchi, Li, Xiang, Hao, Yijie, Zhang, Huafeng“…Here, through immunoprecipitation and mass spectrum data, we show that phosphoglycerate mutase 5 (PGAM5) deacetylation enhances malic enzyme 1 (ME1) metabolic enzyme activity to promote lipid synthesis and proliferation of liver cancer cells. …”
Publicado 2023
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389“…In contrast with the mammalian systems, fumarase and NAD-linked "malic" enzyme were isolated primarily from the intermembrane space fraction of the worm mitochondria. …”
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390por Teh, Huey Fang, Neoh, Bee Keat, Hong, May Ping Li, Low, Jaime Yoke Sum, Ng, Theresa Lee Mei, Ithnin, Nalisha, Thang, Yin Mee, Mohamed, Mohaimi, Chew, Fook Tim, Yusof, Hirzun Mohd., Kulaveerasingam, Harikrishna, Appleton, David R.“…Levels of metabolites involved in glycolysis revealed interesting divergence of flux towards glycerol-3-phosphate, while carbon utilization differences in the TCA cycle were proven by an increase in malic acid/citric acid ratio. Apart from insights into the regulation of enhanced lipid production in oil palm, these results provide potentially useful metabolite yield markers and genes of interest for use in breeding programmes.…”
Publicado 2013
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391“…On the other hand, rationally-based metabolic engineering, like genetic manipulation for pathway design, has becoming increasingly important to this field and has been used for the production of several organic acids, such as succinic acid, malic acid and lactic acid. This review investigates recent works on Saccharomyces cerevisiae and Escherichia coli, as well as the strategies to improve tolerance towards these chemicals.…”
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392por Gdynia, Georg, Sauer, Sven W., Kopitz, Jürgen, Fuchs, Dominik, Duglova, Katarina, Ruppert, Thorsten, Miller, Matthias, Pahl, Jens, Cerwenka, Adelheid, Enders, Markus, Mairbäurl, Heimo, Kamiński, Marcin M., Penzel, Roland, Zhang, Christine, Fuller, Jonathan C., Wade, Rebecca C., Benner, Axel, Chang-Claude, Jenny, Brenner, Hermann, Hoffmeister, Michael, Zentgraf, Hanswalter, Schirmacher, Peter, Roth, Wilfried“…Consistently, we observe an increase in the expression of a key enzyme of glutaminolysis, malic enzyme 1, in advanced colon cancer. Moreover, pharmaceutical inhibition of glutaminolysis sensitizes tumour cells to HMGB1 providing a basis for a therapeutic strategy for treating cancer.…”
Publicado 2016
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393“…This paper reports on the recognition of sweat latent fingerprints using green-emitting, environment-friendly carbon dots prepared with DL-malic acid and ethylenediamine, and the exploration of impacting factors in the development process of fingerprints. …”
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394“…The results of partial least squares discrimination analysis (PLS-DA) confirmed that the metabolites contributed to the discrimination of the wines were 2,3-butanediol, ethyl acetate, malic acid, valine, succinic acid, lactic acid, tartaric acid, glycerol, gallic acid, choline, proline, and alanine.…”
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395por Saraiva, Ariana, Carrascosa, Conrado, Ramos, Fernando, Raheem, Dele, Lopes, Maria, Raposo, António“…The presence of organic acids (malic acid), amino acids and relevant amounts of minerals, such as potassium, calcium, zinc and manganese, make maple syrup unique. …”
Publicado 2022
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396“…The osmolality and concentrations of soluble sugars were less in saps of Li(1) – Li(2), whereas the concentrations of malic acid, K(+) and other detected ions were significantly higher in saps of mutants than in WT. …”
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397por Ceccarelli, Marcello, Diotallevi, Aurora, Andreoni, Francesca, Vitale, Fabrizio, Galluzzi, Luca, Magnani, Mauro“…In particular, the polymorphism 390T>G in the malic enzyme gene has been exploited to develop a high-resolution melt (HRM)-based assay to rapidly differentiate the genotype 390T, associated with zymodemes MON-1, MON-72 and MON-201, evidencing a partial agreement between genotyping results and MLEE. …”
Publicado 2018
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398por Atkins, Hannah M., Bharadwaj, Manish S., O’Brien Cox, Anderson, Furdui, Cristina M., Appt, Susan E., Caudell, David L.“…FAD (p = 0.004), tryptophan (p = 0.0004) and malic acid (p = 0.03) were significantly decreased in endometrium from NHPs with endometriosis compared to normal endometrium. …”
Publicado 2019
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399“…In addition, by performing a review of previous studies, we demonstrated that, as suggested, NADP-dependent malic enzyme-2 is a candidate for local adaptation in salmon from the Iberian Peninsula. …”
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400por Abudureheman, Buhailiqiemu, Zhou, Xinyue, Shu, Xipan, Chai, Ziqi, Xu, Yongping, Li, Shuying, Tian, Jinhu, Pan, Haibo, Ye, Xingqian“…The total fat (7 ± 0.4 and 5 ± 0.1 mg/100 g), soluble sugar (23 ± 0.6 and 12 ± 1.4 g/100 g), titratable acidity (18 ± 2.5% and 14 ± 1.3%) content, and energy value (330.86 and 314.41 kcal/100 g) of B. nummularia was significantly higher than that of B. atrocarpa fruits. Both species contain malic acid, acetic acid, tartaric acid, citric acid and fumaric acid, in which, malic acid is the dominant organic acid. …”
Publicado 2022
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