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  1. 661
    “…During this stage, the entire transcriptional repertoire of the C(4) NADP-malic enzyme type is detected at low levels compared to a significant increase in true leaves. …”
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  2. 662
    por Yin, Xinyou, Struik, Paul C.
    Publicado 2018
    “…Modelled NADPH and ATP production were compared with requirements. For malic‐enzyme (ME) subtypes, c. 50% of electron flux is CET, occurring predominantly in BS cells for standard NADP‐ME species, but in a ratio of c. 6 : 4 in BS : M cells for NAD‐ME species. …”
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  3. 663
    “…Among the increased metabolites in the TCA cycle, malic acid was the most crucial biomarker for fish survival. …”
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  4. 664
    “…Our findings revealed multiple overlooked therapeutic candidates with important bioactivity and established druggability but with unknown expression and function in SCI including the upregulated purine nucleoside phosphorylase (PNP), cathepsins A, H, Z (CTSA, CTSH, CTSZ) and proteasome protease PSMB10, as well as the downregulated ATP citrate lyase (ACLY), malic enzyme (ME1) and sodium-potassium ATPase (ATP1A3), amongst others. …”
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  5. 665
    por Sun, Anqi, Ban, Zhan, Mu, Li, Hu, Xiangang
    Publicado 2018
    “…A metabolomics analysis of cells exposed to nanosilver (nAg) integrates volcano plots (t‐tests and fold change analysis), partial least squares‐discriminant analysis (PLS‐DA), and significance analysis of microarrays (SAM) and identifies six metabolites (l‐aspartic acid, l‐malic acid, myoinositol, d‐sorbitol, citric acid, and l‐cysteine). …”
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  6. 666
    “…It was determined that organic molecules, such as succinic acid, lactic acid, malic acid, and glutathione, which are generated in metabolism process, played important role in the reduction of gold ions. …”
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  7. 667
  8. 668
    “…Schizosaccharomyces pombe totally consumes malic acid while Lachancea thermotolerans produces lactic acid, avoiding excessive deacidification of musts with low acidity in warm viticulture areas. …”
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  9. 669
    “…Particularly, the PdP variety appears richer in antioxidants compounds (i.e., chlorogenic acids and lycopene) and organic acids (i.e., glutamic and malic acids) than does CIL. Additionally, both varieties display different profiles of volatile bioactive compounds and they are differently influenced by the storage time. …”
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  10. 670
    “…Five free sugars (fructose, glucose, sucrose, gentiobiose, gentianose) were identified in all gentian teas studied, as well as six organic acids (malic, citric, tartaric, oxalic, succinic, quinic). …”
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  11. 671
  12. 672
    “…Results: Sucrose significantly decreased in all fermented samples as well as malic acid, converted to lactic acid by malolactic fermentation. …”
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  13. 673
    “…According to the computational results, the hydrogels crosslinked with succinic, aspartic, maleic and malic acids were selected as the best candidates to be synthesized and evaluated experimentally. …”
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  14. 674
  15. 675
    “…CA treatment inhibited the increase in total soluble solids (TSS), sucrose, and fructose in the first week after fruit harvest, but then their content was significantly higher in CA‐treated fruits than that in the control group. The decrease in malic acid and citric acid was significantly prevented by CA treatment. …”
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  16. 676
  17. 677
    “…Metabolites upregulated under H(2)S exposure (7.5 μM) were related to inflammation, and included (6Z, 9Z, 12Z)-octadecatrienoic acid, choline phosphate, and malic acid, while hexadecanoic acid was downregulated. …”
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  18. 678
    “…Ethylene also elicited sucrose hydrolysis and malic acid catabolism, with the major effect seen after 4 days of ethylene exposure. …”
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  19. 679
    “…We found that metabolite and lipid alterations exhibit apparent correlation with the course of disease in these patients, indicating that the development of COVID-19 affected their whole-body metabolism. In particular, malic acid of the TCA cycle and carbamoyl phosphate of the urea cycle result in altered energy metabolism and hepatic dysfunction, respectively. …”
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  20. 680
    “…The fresh fruits were analyzed with the high performance liquid chromatography (HPLC) technique for the purpose of identifying and quantifying the content of glucose, fructose and sucrose, as well as malic, citric, fumaric and shikimic acids. However, the content of individual sugars and organic acids differed by locations as well as by growing year within the same wild fruit species. …”
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