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  1. 661
    “…During this stage, the entire transcriptional repertoire of the C(4) NADP-malic enzyme type is detected at low levels compared to a significant increase in true leaves. …”
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    C(3) cotyledons are followed by C(4) leaves: intra-individual transcriptome analysis of Salsola soda (Chenopodiaceae)
  2. 662
    por Yin, Xinyou, Struik, Paul C.
    Publicado 2018
    “…Modelled NADPH and ATP production were compared with requirements. For malic‐enzyme (ME) subtypes, c. 50% of electron flux is CET, occurring predominantly in BS cells for standard NADP‐ME species, but in a ratio of c. 6 : 4 in BS : M cells for NAD‐ME species. …”
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    The energy budget in C(4) photosynthesis: insights from a cell‐type‐specific electron transport model
  3. 663
    “…Among the increased metabolites in the TCA cycle, malic acid was the most crucial biomarker for fish survival. …”
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    Boosted TCA cycle enhances survival of zebrafish to Vibrio alginolyticus infection
  4. 664
    “…Our findings revealed multiple overlooked therapeutic candidates with important bioactivity and established druggability but with unknown expression and function in SCI including the upregulated purine nucleoside phosphorylase (PNP), cathepsins A, H, Z (CTSA, CTSH, CTSZ) and proteasome protease PSMB10, as well as the downregulated ATP citrate lyase (ACLY), malic enzyme (ME1) and sodium-potassium ATPase (ATP1A3), amongst others. …”
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    Combined Transcriptomics, Proteomics and Bioinformatics Identify Drug Targets in Spinal Cord Injury
  5. 665
    por Sun, Anqi, Ban, Zhan, Mu, Li, Hu, Xiangang
    Publicado 2018
    “…A metabolomics analysis of cells exposed to nanosilver (nAg) integrates volcano plots (t‐tests and fold change analysis), partial least squares‐discriminant analysis (PLS‐DA), and significance analysis of microarrays (SAM) and identifies six metabolites (l‐aspartic acid, l‐malic acid, myoinositol, d‐sorbitol, citric acid, and l‐cysteine). …”
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    Screening Small Metabolites from Cells as Multifunctional Coatings Simultaneously Improves Nanomaterial Biocompatibility and Functionality
  6. 666
    “…It was determined that organic molecules, such as succinic acid, lactic acid, malic acid, and glutathione, which are generated in metabolism process, played important role in the reduction of gold ions. …”
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    Controllable Biosynthesis and Properties of Gold Nanoplates Using Yeast Extract
  7. 667
    “…In the DSS mice, the levels of lactate, linoleic acid, and malic acid increased significantly in the model group. …”
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    Fecal metabolomic dataset of American ginseng-treated DSS mice: Correlation between ginseng enteric inflammation inhibition and its biological signatures
  8. 668
    “…Schizosaccharomyces pombe totally consumes malic acid while Lachancea thermotolerans produces lactic acid, avoiding excessive deacidification of musts with low acidity in warm viticulture areas. …”
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    Combined Use of S. pombe and L. thermotolerans in Winemaking. Beneficial Effects Determined through the Study of Wines’ Analytical Characteristics
  9. 669
    “…Particularly, the PdP variety appears richer in antioxidants compounds (i.e., chlorogenic acids and lycopene) and organic acids (i.e., glutamic and malic acids) than does CIL. Additionally, both varieties display different profiles of volatile bioactive compounds and they are differently influenced by the storage time. …”
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    Comparative Chemical Compositions of Fresh and Stored Vesuvian PDO “Pomodorino Del Piennolo” Tomato and the Ciliegino Variety
  10. 670
    “…Five free sugars (fructose, glucose, sucrose, gentiobiose, gentianose) were identified in all gentian teas studied, as well as six organic acids (malic, citric, tartaric, oxalic, succinic, quinic). …”
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    Bitter Gentian Teas: Nutritional and Phytochemical Profiles, Polysaccharide Characterisation and Bioactivity
  11. 671
    “…Assays indicated that S. sesuvioides employs the NADP-malic enzyme as the major decarboxylating enzyme. …”
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    C(4)-like photosynthesis and the effects of leaf senescence on C(4)-like physiology in Sesuvium sesuvioides (Aizoaceae)
  12. 672
    “…Results: Sucrose significantly decreased in all fermented samples as well as malic acid, converted to lactic acid by malolactic fermentation. …”
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    Use of Dairy and Plant-Derived Lactobacilli as Starters for Cherry Juice Fermentation
  13. 673
    “…According to the computational results, the hydrogels crosslinked with succinic, aspartic, maleic and malic acids were selected as the best candidates to be synthesized and evaluated experimentally. …”
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    Film Dressings Based on Hydrogels: Simultaneous and Sustained-Release of Bioactive Compounds with Wound Healing Properties
  14. 674
    “…The most important organic acids include malic and citric acids, and they confer the fruit acidity. …”
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    Chemical Composition of Mango (Mangifera indica L.) Fruit: Nutritional and Phytochemical Compounds
  15. 675
    “…CA treatment inhibited the increase in total soluble solids (TSS), sucrose, and fructose in the first week after fruit harvest, but then their content was significantly higher in CA‐treated fruits than that in the control group. The decrease in malic acid and citric acid was significantly prevented by CA treatment. …”
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    Citric acid treatment reduces decay and maintains the postharvest quality of peach (Prunus persica L.) fruit
  16. 676
    “…The Panel concluded that based on the data provided it was not possible to assess the dissociation of DMM into magnesium and malic acid. The Panel further concluded that if DMM dissociates, magnesium would be available following ingestion of DMM and the availability would appear similar to values reported for other sources of magnesium already permitted. …”
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    Evaluation of di‐magnesium malate, used as a novel food ingredient and as a source of magnesium in foods for the general population, food supplements, total diet replacement for weight control and food for special medical purposes
  17. 677
    “…Metabolites upregulated under H(2)S exposure (7.5 μM) were related to inflammation, and included (6Z, 9Z, 12Z)-octadecatrienoic acid, choline phosphate, and malic acid, while hexadecanoic acid was downregulated. …”
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    Evaluation of the Metabolic Effects of Hydrogen Sulfide on the Development of Bombyx mori (Lepidoptera: Bombycidae), Using Liquid Chromatography-Mass Spectrometry-Based Metabolomics
  18. 678
    “…Ethylene also elicited sucrose hydrolysis and malic acid catabolism, with the major effect seen after 4 days of ethylene exposure. …”
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    Continuous Exposure to Ethylene Differentially Affects Senescence in Receptacle and Achene Tissues in Strawberry Fruit
  19. 679
    “…We found that metabolite and lipid alterations exhibit apparent correlation with the course of disease in these patients, indicating that the development of COVID-19 affected their whole-body metabolism. In particular, malic acid of the TCA cycle and carbamoyl phosphate of the urea cycle result in altered energy metabolism and hepatic dysfunction, respectively. …”
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    Plasma metabolomic and lipidomic alterations associated with COVID-19
  20. 680
    “…The fresh fruits were analyzed with the high performance liquid chromatography (HPLC) technique for the purpose of identifying and quantifying the content of glucose, fructose and sucrose, as well as malic, citric, fumaric and shikimic acids. However, the content of individual sugars and organic acids differed by locations as well as by growing year within the same wild fruit species. …”
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    Geographic Variability of Sugars and Organic Acids in Selected Wild Fruit Species
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