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921“…Compared with C. humilis, the expression levels of 3,469 and 3,125 genes were up- and down-regulated in C. glandulosa, respectively, including one PEPC gene, 12 malic acid metabolism genes, 25 citric acid cycle genes, and 194 NAD/NADP metabolism genes. …”
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922“…RESULTS: Oxalic acid showed the highest zone of inhibition (15±1 mm) followed by succinic acid, tartaric acid, fumaric acid, citric acid and malic acid. The combination of two acids did not increase the zone of inhibition significantly. …”
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923“…A highly significant down-regulation of genes involved in hepatic lipogenesis including acetyl CoA carboxylase (ACC), fatty acid synthase (FAS), malic enzyme (ME), and lipoprotein lipase (LPL) was observed in the liver of chickens fed MC. …”
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924por Wei, Lingzhi, Mao, Wenwen, Jia, Meiru, Xing, Sinian, Ali, Usman, Zhao, Yaoyao, Chen, Yating, Cao, Minglin, Dai, Zhengrong, Zhang, Kai, Dou, Zhechao, Jia, Wensuo, Li, Bingbing“…We found that FaMYB44.2 negatively regulates soluble sugar accumulation and malic acid content and represses the expression of numerous structural genes, including FaSPS3, a key gene in sucrose accumulation. …”
Publicado 2018
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925por Dickinson, Elizabeth, Rusilowicz, Martin J., Dickinson, Michael, Charlton, Adrian J., Bechtold, Ulrike, Mullineaux, Philip M., Wilson, Julie“…Other metabolite concentrations that change as a result of treatment include phosphoric acid, malic acid and tetrahydroxychalcone. CONCLUSIONS: Probing metabolomic data with transcriptomic tools provides new insights and could help to identify resilient plant varieties, thereby increasing future crop yield and improving food security. …”
Publicado 2018
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926“…Activity of lactate dehydrogenase along with glucose-6- and fructose-1, 6-bis phosphatase, glucose-6-phosphate dehydrogenase and NADP-malic enzyme increased but malate dehydrogenase decreased in all tissues. …”
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927por Hashim, Nurul Azmir Amir, Ab-Rahim, Sharaniza, Suddin, Leny Suzana, Saman, Mohd Shahril Ahmad, Mazlan, Musalmah“…These metabolites include pyruvic acid, glucose, lactic acid, malic acid, fumaric acid, 3-hydroxybutyric acid, tryptophan, phenylalanine, tyrosine, creatinine and ornithine. …”
Publicado 2019
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928por Martinez, Silvia Juliana, Bressani, Ana Paula Pereira, Dias, Disney Ribeiro, Simão, João Batista Pavesi, Schwan, Rosane Freitas“…Also, it was observed an increase of microbial cells from 0 to 48 h of fermentation. Malic, lactic, and acetic acid were only detected in the bacterial treatments. …”
Publicado 2019
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929por Liang, Zi-Hong, Jia, Yan-Bo, Li, Zi-Ru, Li, Min, Wang, Mei-Ling, Yun, Yong-Li, Yu, Li-Jun, Shi, Lei, Zhu, Run-Xiu“…A panel consisting of pseudouridine, malic acid, hypoxanthine, 3,4-dihydroxybutyric acid, fructose and inositol was identified. …”
Publicado 2019
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930“…Unstressed cells were found to use glucose as their primary energy source with high concentrations of metabolites involved in glycolysis and organic acid synthesis, such as lactic acid, acetic acid, propanoic acid, malic acid, and 2-butenedioic acid being present in these cells. …”
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931por Darbani, Behrooz, Stovicek, Vratislav, van der Hoek, Steven Axel, Borodina, Irina“…Among the tested transporters, the Mae1(p) from Schizosaccharomyces pombe had the highest activity toward succinic, malic, and fumaric acids and resulted in 3-, 8-, and 5-fold titer increases, respectively, in S. cerevisiae, while not affecting growth, which was in contrast to the tested transporters from the tellurite-resistance/dicarboxylate transporter (TDT) family or the Na(+) coupled divalent anion–sodium symporter family. …”
Publicado 2019
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932por Zhu, Jing, Zhang, Mu, Han, Tingli, Wu, Hua, Xiao, Zhibo, Lin, Shihui, Wang, Chuanjiang, Xu, Fang“…In particular, the 4 common metabolites in the four groups were 4-hydroxyphenylacetic acid; carbostyril, 3-ethyl-4,7-dimethoxy (35.8%); malic acid peak 1; and oxalic acid. The concentration of 4-hydroxyphenylacetic acid in sepsis patients decreased with a decrease of the GCS. …”
Publicado 2019
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933por Khanna, Kanika, Sharma, Anket, Ohri, Puja, Bhardwaj, Renu, Abd_Allah, Elsayed F., Hashem, Abeer, Ahmad, Parvaiz“…An increase in the levels of phenolic compounds (total phenols, flavonoids, anthocyanins), osmoprotectants (total osmolytes, carbohydrates, reducing sugars, trehalose, proline, glycine betaine, free amino acids) and organic acids (fumaric, succinic, citric, malic acid) were reflected in infected plants, showing further enhancement after application of biocontrol agents. …”
Publicado 2019
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934por Wang, Huanjun, Wang, Xiaoming, Qi, Dongmei, Sun, Mengjia, Hou, Qingqing, Li, Yunlun, Jiang, Haiqiang“…Moreover, multivariate statistical analysis revealed metabolic markers of rhythm homeostasis, such as arginine, proline, phenylalanine, citric acid, l-malic acid, succinic acid, etc., accompanied by an imbalance in hypertension. …”
Publicado 2020
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935por Ingallina, Cinzia, Sobolev, Anatoly P., Circi, Simone, Spano, Mattia, Fraschetti, Caterina, Filippi, Antonello, Di Sotto, Antonella, Di Giacomo, Silvia, Mazzoccanti, Giulia, Gasparrini, Francesco, Quaglio, Deborah, Campiglia, Enio, Carradori, Simone, Locatelli, Marcello, Vinci, Giuliana, Rapa, Mattia, Ciano, Salvatore, Giusti, Anna Maria, Botta, Bruno, Ghirga, Francesca, Capitani, Donatella, Mannina, Luisa“…All cultivars in each harvesting period showed a THC content below the Italian legal limit, although in general THC content increased over the season. Citric acid, malic acid and glucose showed the highest content in the late flowering period, whereas the content of proline drastically decreased after June in all cultivars. …”
Publicado 2020
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936por Chandra, Rosita D., Siswanti, Chandra A., Prihastyanti, Monika N. U., Heriyanto, Limantara, Leenawaty, Brotosudarmo, Tatas H. P.“…The breakdown of the starch during the ripening stages resulted in an increase of its sugar compounds, such as sucrose, fructose, and glucose, as well as its dominant organic acids, such as malic acid, oxalic acid, and citric acid, which were observed using gas chromatography-mass spectrometry (GC-MS) during the ripening stages. …”
Publicado 2020
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937por Balsa, Eduardo, Perry, Elizabeth A., Bennett, Christopher F., Jedrychowski, Mark, Gygi, Steven P., Doench, John G., Puigserver, Pere“…The top hit of the screen is the cytosolic Malic Enzyme (ME1), that is sufficient to enable survival and proliferation of CI mutant cells under nutrient stress conditions. …”
Publicado 2020
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938por Nazir, Yusuf, Halim, Hafiy, Prabhakaran, Pranesha, Ren, Xiaojie, Naz, Tahira, Mohamed, Hassan, Nosheen, Shaista, Mustafa, Kiren, Yang, Wu, Abdul Hamid, Aidil, Song, Yuanda“…Supplementation with the phytohormones at 24 h exhibited the maximum impact on reducing the level of reactive oxygen species (ROS) and malondialdehyde (MDA), as well as augmented the antioxidants (superoxide dismutase and catalase) and key metabolic enzymes involved in lipogenesis (malic, glucose-6-phosphate dehydrogenase and ATP-citrate lyase) in comparison to the control and other time points. …”
Publicado 2020
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939“…Fermentation characteristics, such as the conversion of malic acid into lactic acid and acetoin production, were retrieved and could be attributed to specific microorganisms, namely Pediococcus damnosus and Acetobacter species, respectively. …”
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940por Bushau-Sprinkle, Adrienne, Barati, Michelle T., Gagnon, Kenneth B., Khundmiri, Syed Jalal, Kitterman, Kathleen, Hill, Bradford G., Sherwood, Amanda, Merchant, Michael, Rai, Shesh N., Srivastava, Sudhir, Clark, Barbara, Siskind, Leah, Brier, Michael, Hata, Jessica, Lederer, Eleanor“…Non-treated kidneys were also used for LC-MS analysis to evaluate kidney ATP abundance, and electron microscopy (EM) was utilized to evaluate mitochondrial morphology and number. (3) Results: KO mouse kidneys exhibit significant increases in malic enzyme and glucose-6 phosphate dehydrogenase activity under baseline conditions but in no other gluconeogenic or glycolytic enzymes. …”
Publicado 2020
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