Mostrando 2,701 - 2,720 Resultados de 103,171 Para Buscar '"Mannerism"', tiempo de consulta: 0.74s Limitar resultados
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    “…We next detected EMT and proliferation markers. miR-26b-5p was shown to exert its function in a β-catenin-dependent manner. CONCLUSION: Taken together, our results showed that miR-26b-5p inhibits proliferation, migration, invasion and EMT by degrading β-catenin.…”
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    “…NSUN2 could promote gastric cancer cell proliferation through repressing p57(Kip2) in an m(5)C-dependent manner. Our findings suggested that NSUN2 acted as an oncogene through promoting gastric cancer development by repressing p57(Kip2) in an m(5)C-dependent manner, which may provide a novel therapeutic target against gastric cancer.…”
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    “…Mechanistically, ALKBH5 posttranscriptionally activated PER1 by m6A demethylation in an m6A-YTHDF2-dependent manner. PER1 upregulation led to the reactivation of ATM-CHK2-P53/CDC25C signalling, which inhibited cell growth. …”
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    “…In vivo experiments confirmed that shear rate gradients accelerate thrombosis in a VWF-dependent manner. Together, this study characterizes a process of plasma VWF-dependent accelerated thrombosis on weak adhesive proteins such as, fibrinogen in the presence of shear rate gradients.…”
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  15. 2715
    “…In addition, MIF can be secreted by tubular cells and may contribute to cyst growth in an autocrine manner. However, the underlying mechanisms leading to induction of MIF in cyst-lining cells remained elusive. …”
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    “…These results reveal previously unrecognized dynamics of BRD4 and P-TEFb after UV stress and regulation of gene transcription by BRD4 acting as either activator or repressor in a context-dependent manner.…”
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