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301por Chiang, Ivy K N, Graus, Matthew S, Kirschnick, Nils, Davidson, Tara, Luu, Winnie, Harwood, Richard, Jiang, Keyi, Li, Bitong, Wong, Yew Yan, Moustaqil, Mehdi, Lesieur, Emmanuelle, Skoczylas, Renae, Kouskoff, Valerie, Kazenwadel, Jan, Arriola‐Martinez, Luis, Sierecki, Emma, Gambin, Yann, Alitalo, Kari, Kiefer, Friedmann, Harvey, Natasha L, Francois, Mathias“…Here, we show that a BEC‐specific transcription factor, SOX7, plays a crucial role in a non‐cell‐autonomous manner by modulating the transcription of angiocrine signals to pattern lymphatic vessels. …”
Publicado 2023
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303por Basse, Astrid L., Nielsen, Karen N., Karavaeva, Iuliia, Ingerslev, Lars R., Ma, Tao, Havelund, Jesper F., Nielsen, Thomas S., Frost, Mikkel, Peics, Julia, Dalbram, Emilie, Dall, Morten, Zierath, Juleen R., Barrès, Romain, Færgeman, Nils J., Treebak, Jonas T., Gerhart-Hines, Zachary“…Moreover, adipose NAMPT depletion improved the ability of animals to defend body temperature during cold stress but in a time-of-day-independent manner. Thus, our findings reveal that peripheral molecular clocks and metabolic biorhythms are shaped in a highly tissue-specific manner by NAMPT-dependent NAD(+) synthesis.…”
Publicado 2023
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304por Madar, Jonathan, Tiwari, Namrata, Smith, Cristina, Sharma, Divya, Shen, Shanwei, Elmahdi, Alsiddig, Qiao, Liya Y.“…Here we show that chemogenetic activation or nociceptor-targeted deletion of Piezo2 is sufficient to regulate colonic mechanical sensitivity in a sex dependent manner. Clozapine N-oxide-induced activation of Piezo2;hM3Dq-expressing sensory neurons evokes colonic hypersensitivity in male mice, and causes dyspnea in female mice likely due to effects on lung sensory neurons. …”
Publicado 2023
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305“…Here, we assessed the mixing of parental mitochondria carefully by live-cell microscopy and developed an algorithm to determine the degree of mitochondrial mixing in a quantitative manner. We found that parental mitochondria in fission yeast cells were mixed progressively as meiosis progressed. …”
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307por Dorigo, Alessandro, Valishetti, Komali, Hetsch, Florian, Matsui, Hideaki, Meier, Jochen C., Namikawa, Kazuhiko, Köster, Reinhard W.Enlace del recurso
Publicado 2023
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308por Rey‐Millet, Martin, Pousse, Mélanie, Soithong, Chan, Ye, Jing, Mendez‐Bermudez, Aaron, Gilson, Eric“…These findings unveil that the subtelomere transcriptome associated with senescence is determined in a chromosome‐end‐specific manner according to the type of higher‐order chromatin structure.…”
Publicado 2023
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309por Kanzaki, Yuki, Matoba, Ryo, Kimura, Shuhei, Hosokawa, Mio M., Shiode, Yusuke, Doi, Shinichiro, Morita, Tetsuro, Kanzaki, Sayumi, Takasu, Ippei, Tanikawa, Atsuhiro, Morizane, Yuki“…CONCLUSIONS: The findings suggest that ERM impairs the inner retinal layer in a traction force-dependent manner. FINANCIAL DISCLOSURE(S): The author(s) have no proprietary or commercial interest in any materials discussed in this article.…”
Publicado 2023
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312por Hopkin, Sophie J, Pezhman, Laleh, Begum, Jenefa, Kavanagh, Dean, McGettrick, Helen M, Iqbal, Asif J, Chimen, MyriamEnlace del recurso
Publicado 2023
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313por Chauvin, Camille, Radulovic, Katarina, Boulard, Olivier, Delacre, Myriam, Waldschmitt, Nadine, Régnier, Paul, Legris, Gauthier, Bouchez, Clément, Sleimi, Mohamed-Yassine, Rosenstiel, Philip, Darrasse-Jèze, Guillaume, Chamaillard, Mathias, Poulin, Lionel F.Enlace del recurso
Publicado 2023
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314“…This is especially so when we consider that such practice was grounded in notably wide reading across disciplines and in world literature, a highly developed analytical manner that was inseparable from a notable literary talent in composing published texts, and an open-mindedness about the gathering of data sources in ways that some today find methodologically much too promiscuous. …”
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315por Hu, Juan, Yan, Jing, Chen, Yijie, Li, Xiaohui, Yang, Liu, Di, Haiyu, Zhang, Huihui, Shi, Yewen, Zhao, Junjie, Shi, Yanxia, Xu, Yinglong, Ren, Xiaoyong, Wang, ZhenghuiEnlace del recurso
Publicado 2023
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316“…The spiking activity of cerebellar nuclear (CN) cells was transsynaptically entrained to the frequency of AC stimulation in an intensity and frequency-dependent manner. Interestingly, there was a tuning curve for modulation where the frequencies in the midrange (100 and 150 Hz) were more effective, although the stimulation frequency for maximum modulation differed for each CN cell with slight dependence on the stimulation amplitude. …”
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317“…Traits that were not directly related to cardiac output, such as arterial and venous diameter, and red blood cell velocities did not respond to hypoxia in a family specific manner. CONCLUSION: Zebrafish families vary in their plastic response to hypoxia. …”
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319“…The factors that determine the manner of tumor growth are as yet imperfectly understood. …”
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