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  1. 3821
    “…Conclusion: The WBZ ointment can inhibit the proliferation of the keloid-derived fibroblasts in a time- and dose- dependent manner.…”
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    The Effects of Wubeizi Ointment on the Proliferation of Keloid-Derived Fibroblasts
  2. 3822
    por Thomas, Laura E., Pemstein, Daniel
    Publicado 2015
    “…Our results suggest that people are vulnerable to the influence of a limited viewpoint when forming representations of others in a manner that shapes their strategic choices.…”
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    What you see is what you get: webcam placement influences perception and social coordination
  3. 3823
    “…Results from the multisensory processing literature make it clear that the senses interact on a more intimate manner than previously assumed. These interactions raise questions regarding the manner in which multisensory information is maintained in working memory. …”
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    A multisensory perspective of working memory
  4. 3824
    por Ge, Ying, Feng, Wei
    Publicado 2012
    “…CONCLUSION: Through the assessment of action research, the group training manner is a useful group consulting manner to make family legal education for adolescent parents. …”
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    Action Research on Group Consulting of Family Legal Education for Adolescent Parents in China
  5. 3825
    “…Inhalation of diacetone alcohol significantly reduced murine locomotor activity in a dose-dependent manner, and this effect was not observed in olfaction-impaired mice. …”
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    Sedative effects of inhaled essential oil components of traditional fragrance Pogostemon cablin leaves and their structure–activity relationships
  6. 3826
    por Zhu, Yan-zhen, Wang, Wei, Xian, Na, Wu, Bing
    Publicado 2016
    “…Terminal deoxynucleotidyl transferase-mediated dUTP nick end labeling assay demonstrated that hypoxia induced neuronal apoptosis in a time-dependent manner, with a greater number of apoptotic cells with longer hypoxic exposure. …”
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    Inhibition of TYRO3/Akt signaling participates in hypoxic injury in hippocampal neurons
  7. 3827
    “…Moreover, YF-18 inhibited A549-luciferase cell xenograft tumor growth in a dose-dependent manner. The findings indicate that YF-18 bears therapeutic potentials for lung cancer.…”
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    Matrine derivative YF-18 inhibits lung cancer cell proliferation and migration through down-regulating Skp2
  8. 3828
    “…Tubulin polymerization and immunostaining experiments revealed that 10s potently inhibited tubulin polymerization and disrupted tubulin microtubule dynamics in a manner similar to CA-4. Moreover, 10s effectively induced SGC-7901 cell cycle arrest at the G(2)/M phase in both concentration- and time-dependent manners. …”
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    Synthesis and bioevaluation of N,4-diaryl-1,3-thiazole-2-amines as tubulin inhibitors with potent antiproliferative activity
  9. 3829
    “…In addition, abdominal skin wounds healed in an identical manner in the mutant and wild type mice. CONCLUSIONS: The absence of a dermatan sulfate chain on decorin does not appear to overtly influence its functional properties in vivo.…”
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    Absence of the dermatan sulfate chain of decorin does not affect mouse development
  10. 3830
    “…This strategy enables perturbation of the metabolic and regulatory networks in a modular, parallel, and high-throughput manner. We demonstrate the application of CRISPR-AID not only to increase the production of β-carotene by 3-fold in a single step, but also to achieve 2.5-fold improvement in the display of an endoglucanase on the yeast surface by optimizing multiple metabolic engineering targets in a combinatorial manner.…”
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    Combinatorial metabolic engineering using an orthogonal tri-functional CRISPR system
  11. 3831
    “…Previously, we have shown that DNA methylation marks exons and that a loss of DNA methylation alters splicing patterns in a genome-wide manner. To investigate the influence of DNA methylation on splicing of individual genes, we developed a method to manipulate DNA methylation in vivo in a site-specific manner using the deactivated endonuclease Cas9 fused to enzymes that methylate or demethylate DNA. …”
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    The importance of DNA methylation of exons on alternative splicing
  12. 3832
    “…Compounds 1–9 and 13–16 significantly inhibited PTP1B activity in a dose dependent manner, with IC(50) values ranging from 1.9–13.6 μM. …”
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    Protein Tyrosine Phosphatase 1B Inhibitors from the Roots of Cudrania tricuspidata
  13. 3833
    “…The vast majority of cortical projection neurons and certain classes of glial cells are generated by radial glial progenitor cells in a highly orchestrated manner. Recent studies employing single cell analysis and clonal lineage tracing suggest that neural stem cell and radial glial progenitor lineage progression are regulated in a profound deterministic manner. …”
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    Epigenetic cues modulating the generation of cell‐type diversity in the cerebral cortex
  14. 3834
    por Pantsar, Markus
    Publicado 2019
    “…With proto-arithmetical ability, based on the core cognitive abilities for subitizing and estimation, numerosities can be treated in a limited and/or approximate manner. With arithmetical ability, numerosities are processed (counted, operated on) systematically in a discrete, linear, and unbounded manner. …”
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    The Enculturated Move From Proto-Arithmetic to Arithmetic
  15. 3835
    por Awakawa, Takayoshi, Abe, Ikuro
    Publicado 2019
    “…AmbP3 transfers the dimethylallyl group on C-2 of hapalindole U in the reverse manner, but on C-2 of its C-10 stereoisomer in the normal manner. …”
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    Molecular basis for the plasticity of aromatic prenyltransferases in hapalindole biosynthesis
  16. 3836
    “…Translational Statistics proposes to promote the use of Statistics within research and improve the communication of statistical findings in an accurate and accessible manner to diverse audiences. When statistical models become more complex, it becomes harder to evaluate the role of explanatory variables on the response. …”
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    Visualising statistical models using dynamic nomograms
  17. 3837
    “…As safe, high-quality care requires an integrated approach, each element must be supported together, i.e., in an integrated manner to ensure that anaesthesia care reaches those who need it, and in the safest possible manner. …”
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    The path to safe and accessible anaesthesia care
  18. 3838
    “…CONCLUSION: Brick plots represent a new approach to visualize complex immunological data in an intuitive manner.…”
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    Brick plots: an intuitive platform for visualizing multiparametric immunophenotyped cell clusters
  19. 3839
    “…Therefore, methods to construct dynamic microscale concentration gradients in a spatially controlled manner are needed to provide more realistic research environments. …”
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    Stepwise construction of dynamic microscale concentration gradients around hydrogel-encapsulated cells in a microfluidic perfusion culture device
  20. 3840
    “…Digital health is a rapidly developing field which is positioned to transform the manner in which healthcare is delivered, especially amongst adolescents and young adults. …”
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    Reconsidering reviews: the role of scoping reviews in digital medicine and pediatrics
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