“…Mutations in the gate shift the equilibrium of transitions in a manner consistent with a progressive destabilization of this region during pore opening. …”
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“…These results suggest a continuous change of synaptic converging of RGC synaptic inputs in an RGC type-dependent manner. Besides, light deprivation impairs both the development of dendritic and receptive fields.…”
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“…We found that prematurity affected these networks in a sleep state-specific manner, and the differences between groups were also frequency-selective, involving brain-wide connections. …”
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“…The purpose of the study is to discover the weapon used, the cause, and the manner of death, with particular interest in this case due to the dismemberment. …”
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“…Providing relatable context is key to communicating to the public the justification and outputs of GM crop research in a non-scientific manner so as to maximize societal comprehension.…”
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“…An fMRI experiment reveals distinct brain regions that respond in a graded manner as humans process distance information across increasing spatial scales.…”
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“…When universities need to make staffing cuts to balance the books, do they always do so in the fairest and most rational manner? [Image: see text]…”
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“…MSREqPCR provides high multiplexing capabilities also when starting with limited amount of DNA-like cfDNA to validate many targets in a time- and cost-effective manner. Multiplex design is challenging and cumbersome to define specific primers in an effective manner, and no suitable software tools are freely available for high-throughput primer design in a time-effective manner and to automatically annotate the resulting primers with known SNPs, CpG, repeats, and RefSeq genes. …”
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“…Within this framework, users are invited, through a user-friendly Python interpreter, to implement physics analyses in a very simple manner. A C++ code is then automatically generated, compiled and executed. …”
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“…ALS also exhibited various regulatory effects on the PI3K/Akt and mitogen-activated protein kinase (MAPK) pathways, the two dominant RAS signaling pathways, and induced apoptosis and autophagy in a RAS allele-specific manner. Combined treatment with ALS and selumetinib enhanced the regulatory effects of ALS on apoptosis and autophagy in CRC cell lines in a RAS allele-specific manner. …”
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“…The CCK-8 data showed that the viability of H1299 cells was significantly inhibited by GA in a dose- and time-dependent manner. DAPI staining, Annexin-V/PI staining and wound-healing data showed that GA exerted pro-apoptotic and anti-migratory effects on H1299 cells in a dose-dependent manner. …”
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“…It was found that most Mexican children are not receiving their full vaccine schedule in a timely manner. Concerning children under twelve months of age, the coverage targets for National Immunization of 95 % was not reached for either vaccine, and only 2.94 % (95 % CI 0.92–9.01) who had been receiving a three-vaccine scheme were considered as fully immunized in a timely manner. …”
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“…GILZ was induced in a Dex-dependent manner on both day1 and day4. In the differentiation phase, PPARG2 expression was not changed by Dex, but GILZ was induced in a similar Dex-dependent manner. …”
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“…The current study provides evidence that chronic lung exposure to fungal arthroconidia affects B-CLL development in a manner dependent on fungal genotype. Correlative studies suggest that fungal species differences in the modulation of nonleukemic hematopoietic cells are involved.…”
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“…This group comprised 57 girls and 65 boys. For the manner of the death, natural causes were the most common cause (n = 91, 74.5%). …”
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“…SIMPLE SUMMARY: Insulin and glucose affect the biofilm formation of both Gram-positive and Gram-negative bacteria over the physiologic range in a manner that is dependent on the ratio of insulin to glucose. …”
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“…Furthermore, we discussed the clinical application of m(6)A modifications for colorectal cancer diagnosis, prognosis, and treatment and provided guides in clinical practice. m(6)A modification and m(6)A regulators play significant roles in the occurrence and development of colorectal cancer by regulating the stability and translation of mRNAs, the maturation of miRNAs, and the function of lncRNAs. m(6)A regulators can play biological roles in colorectal cancer through m(6)A-dependent manner or m(6)A-independent manner. Multiplies of internal factors, including miRNAs and lncRNAs, and external factors can also regulate the m(6)A modification by completing with m(6)A regulators in a base complement manner, regulating the expression of m(6)A and mutating the m(6)A site. m(6)A regulators and m(6)A modificantion are diagnostic and prognostic markers for CRC. …”
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“…When present in solution, peptide Hep-I competed for the binding of these cells to type IV collagen- and NC1 domain-coated substrata in a dose-dependent manner. Furthermore, radiolabeled peptide Hep-I in solution also bound to endothelial cells in a dose-dependent and specific manner. …”
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“…Acids, alkalies, salts, and glucosides act in a manner which is in agreement with this rule. Cobra lysin and tetanolysin do not act in conformity with the rule. …”
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