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  1. 4441
    “…Upon administration of drug, T-cell functions were restored in a reversible and titratable manner. We showed that this T-cell switch was universal, as it could be combined with endogenous or transduced T-cell receptors (TCR), as well as chimeric antigen receptors. …”
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    Online Artículo Texto
    CRASH-IT Switch Enables Reversible and Dose-Dependent Control of TCR and CAR T-cell Function
  2. 4442
    “…In myotubes, we show that PGC-1α4 overexpression increases anaerobic glycolysis in a PPARβ-dependent manner and promotes muscle glucose uptake and fat oxidation. …”
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    Enhancement of anaerobic glycolysis – a role of PGC-1α4 in resistance exercise
  3. 4443
    “…PN-GSC-derived TF stimulates MES-GSC proliferation in an iron-dependent manner. DA acts in an autocrine on PN-GSC growth in a DA receptor D1-dependent manner, while in a paracrine it induces TF receptor 1 expression in MES-GSCs to assist iron uptake and thus enhance ferroptotic vulnerability. …”
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    Iron commensalism of mesenchymal glioblastoma promotes ferroptosis susceptibility upon dopamine treatment
  4. 4444
    “…These organoids are formed in a high-throughput manner from the aggregation of endothelial and mesenchymal cells within hydrogel microwells. …”
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    Online Artículo Texto
    Microarrayed human bone marrow organoids for modeling blood stem cell dynamics
  5. 4445
    “…Here, we show that sarcomere cross-sectional area (CSA) varies along its length in a cell type-dependent manner where the reduction in Z-disk CSA relative to the sarcomere center is closely coordinated with mitochondrial network configuration in flies, mice, and humans. …”
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    Online Artículo Texto
    Mitochondrial network configuration influences sarcomere and myosin filament structure in striated muscles
  6. 4446
    “…Using genetically defined models and pharmacological inhibitors, we showed that CDK8 and CDK19 function in a redundant manner to regulate intestinal lineage specification in humans and mice. …”
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    Online Artículo Texto
    CDK8 and CDK19 regulate intestinal differentiation and homeostasis via the chromatin remodeling complex SWI/SNF
  7. 4447
    “…Here, we first put forth PTL’s cholesterol-lowering ability to inhibit cellular uptake of cholesterol in a dose-dependent manner. Its performance was on par with the positive control drug, ezetimibe. …”
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    First Discovery of Cholesterol-Lowering Activity of Parthenolide as NPC1L1 Inhibitor
  8. 4448
    “…Solution FTIR and UV/Vis spectroscopy support the single bond isomerization of the carotenoid in the s-BP manner and subsequent thermal structural reactions as the basis of OCP photoreception.…”
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    Light activation of Orange Carotenoid Protein reveals bicycle-pedal single-bond isomerization
  9. 4449
    “…Results of the MTT assay revealed that DPT significantly reduced the cell viability in a time- and dose-dependent manner. Flow cytometry analysis revealed that DPT induces apoptosis in OSCC cells in a dose-dependent manner. …”
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    Deoxypodophyllotoxin Induces ROS-Mediated Apoptosis by Modulating the PI3K/AKT and p38 MAPK-Dependent Signaling in Oral Squamous Cell Carcinoma
  10. 4450
    “…We demonstrate Hi-LASSO’s outperformance with various intensive experiments in a practical manner. Hi-LASSO will be efficiently and easily performed by using the packages for feature selection. …”
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    Hi-LASSO: High-performance python and apache spark packages for feature selection with high-dimensional data
  11. 4451
    “…The large- and small-bore molecules possessed helicity in atomic arrangements, and their coaxial assembly proceeded in nonstereoselective manner to give both heterohelical and homohelical combinations.…”
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    Target-oriented design of helical nanotube molecules for rolled incommensurate bilayers
  12. 4452
    “…These findings suggest that, distinct from conventional T cells, the accumulation of MAIT cells is restrained by RIPK3 signalling, likely prior to thymic egress, in a manner independent of canonical apoptotic and necroptotic cell death pathways.…”
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    RIPK3 controls MAIT cell accumulation during development but not during infection
  13. 4453
    por D'Souza, Subas
    Publicado 2013
    “…A starter guide that covers Apache Flume in detail.Apache Flume: Distributed Log Collection for Hadoop is intended for people who are responsible for moving datasets into Hadoop in a timely and reliable manner like software engineers, database administrators, and data warehouse administrators…”
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    Apache Flume: distributed log collection for Hadoop
  14. 4454
    por Hoffman, Steve
    Publicado 2015
    “…If you are a Hadoop programmer who wants to learn about Flume to be able to move datasets into Hadoop in a timely and replicable manner, then this book is ideal for you. No prior knowledge about Apache Flume is necessary, but a basic knowledge of Hadoop and the Hadoop File System (HDFS) is assumed.…”
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    Apache Flume: distributed log collection for Hadoop
  15. 4455
    por Koch, Karl-Rudolf
    Publicado 2007
    “…It does so in a simple manner that is easy to comprehend. The book compares traditional and Bayesian methods with the rules of probability presented in a logical way allowing an intuitive understanding of random variables and their probability distributions to be formed.…”
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    Introduction to Bayesian statistics
  16. 4456
    por Mukherjee, Kalyan Kr
    Publicado 2020
    “…Every endeavor has been made to present the underlying principles in a lucid manner without compromising rigour. As for mathematical and statistical pre-requisities, only the elementary knowledge of college Algebra and Probability is assumed.…”
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    Numerical analysis
  17. 4457
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    Search for narrow resonances decaying into $p\bar{p}$ in the reaction $\pi^{-}p \rightarrow p\bar{p}n$
  18. 4458
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    Measurement of the reaction $\pi^{-}p \to \pi^{+}\pi^{-}n$ on a transversely polarized target at 17 GeV
  19. 4459
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    Measurement and analysis of the $\pi^{+}\pi^{+}$ system produced at small momentum transfer in the reaction $\pi^{+}p \to \pi^{+} \pi^{+} n$ at 12.5 GeV
  20. 4460
    por Manners, Millar, John
    Publicado 1867
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    Online Artículo Texto
    Cases of Poisoning by Susumber Berries
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