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  1. 5001
    “…The findings demonstrated the positive effects of high-quality workplace relationships on working manners including higher commitment, lower level of reported job stress, and increased perception of social impact. …”
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    The Impacts of the High-Quality Workplace Relationships on Job Performance: A Perspective on Staff Nurses in Vietnam
  2. 5002
    “…Cytokinins (CKs), a class of phytohormone, regulate root growth in a dose-dependent manner. A certain threshold content of CK is required for rapid root growth, but supraoptimal CK content inhibits root growth, and the mechanism of this inhibition remains unclear in rice. …”
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    Supraoptimal Cytokinin Content Inhibits Rice Seminal Root Growth by Reducing Root Meristem Size and Cell Length via Increased Ethylene Content
  3. 5003
    “…These findings highlight that encapsulation of γ-cyhalothrin mitigates hydrophobic partitioning in a time-dependent manner and influences toxicity in a size-dependent manner. …”
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    Pesticide Encapsulation at the Nanoscale Drives Changes to the Hydrophobic Partitioning and Toxicity of an Active Ingredient
  4. 5004
    “…Treatment with the PHD inhibitor IOX2 or the VHL inhibitor VH032 led mostly to gene activation, majorly via a HIF-dependent manner. These results were also confirmed by qRT-PCR using more specific and/or efficient inhibitors, FG-4592 (PHDs) and VH298 (VHL). …”
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    RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response.
  5. 5005
    “…RVSE inhibited the growth of MCF-7 cells in a dose-dependent manner by inducing apoptosis in the sub-G1 phase. …”
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    Extract of Rhus verniciflua Stokes Induces p53-Mediated Apoptosis in MCF-7 Breast Cancer Cells
  6. 5006
    por Tauber, Devin, Parker, Roy
    Publicado 2019
    “…Our findings define a mechanism by which inflammation activates the ISR in a cell-nonautonomous manner and suggest that inhibition of 15-d-PGJ2 production might be a useful therapeutic strategy in some neuroinflammatory contexts.…”
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    15-Deoxy-Δ(12,14)-prostaglandin J2 promotes phosphorylation of eukaryotic initiation factor 2α and activates the integrated stress response
  7. 5007
    “…Therefore, an exogenous cytokine-free method, where cytokines required for differentiation are provided in an auto/paracrine manner mimicking natural developmental process, is beneficial. …”
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    Exogenous Cytokine-Free Differentiation of Human Pluripotent Stem Cells into Classical Brown Adipocytes
  8. 5008
    “…We have devised a method that can deliver caged molecules into an intracellular parasite, Toxoplasma gondii, that express an uncaging enzyme in a stage-specific manner without affecting host cell biology. This system provides a valuable tool for studying many intracellular parasites.…”
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    Stage-Specific and Selective Delivery of Caged Azidosugars into the Intracellular Parasite Toxoplasma gondii by Using an Esterase-Ester Pair Technique
  9. 5009
    “…Furthermore, significant regional differences of CO poisoning have been detected in the manner of death and the source of CO. CONCLUSION: These findings will be valuable in the targeted prevention of non-fire related CO poisoning in China.…”
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    Non-Fire Related Carbon Monoxide Poisoning in Sichuan, China: A 9-Year Study (2008–2016)
  10. 5010
    por Rohrlack, Thomas
    Publicado 2018
    “…Most of these exploit their prey in a frequency-dependent manner and are therefore particularly well suited to prevent any accumulation of cyanobacteria. …”
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    Low temperatures can promote cyanobacterial bloom formation by providing refuge from microbial antagonists
  11. 5011
    “…Overall, we demonstrate chemical tactics for modification of amyloidogenic peptides in an effective and manageable manner utilizing the coordination capacities and photophysical properties of transition metal complexes.…”
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    Chemical strategies to modify amyloidogenic peptides using iridium(iii) complexes: coordination and photo-induced oxidation
  12. 5012
    “…One of the current developments in drug research is the controlled release formulation of drugs, which can be released in a controlled manner at a specific target in the body. Due to the diverse physical and chemical properties of various drugs, a smart drug delivery system is highly sought after. …”
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    The Impact of Magnesium–Aluminum-Layered Double Hydroxide-Based Polyvinyl Alcohol Coated on Magnetite on the Preparation of Core-Shell Nanoparticles as a Drug Delivery Agent
  13. 5013
    por Zou, Ge, Bai, Jie, Li, Dandan, Chen, Yan
    Publicado 2019
    “…In conclusion, metformin intervention suppressed SKOV3 proliferation and induced apoptosis in a concentration-dependent manner. Metformin also inhibited the invasion and migration of SKOV3 cells. …”
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    Effect of metformin on the proliferation, apoptosis, invasion and autophagy of ovarian cancer cells
  14. 5014
    “…The development of the mammalian retina is a complicated process involving the generation of distinct types of neurons from retinal progenitor cells (RPCs) in a spatiotemporal-specific manner. The progression of RPCs during retinogenesis includes RPC proliferation, cell-fate commitment, and specific neuronal differentiation. …”
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    Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis
  15. 5015
    “…MYC2 also regulates different phytohormone‐signaling pathways in crucial manner. Arabidopsis response regulator 16 (ARR16) is a negative regulator of cytokinin signaling pathways. …”
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    MYC2 regulates ARR16, a component of cytokinin signaling pathways, in Arabidopsis seedling development
  16. 5016
    por Gallagher, Daniel
    Publicado 2019
    “…In this mini-review, I use event-related potential (ERP) studies to test the minimalist program (MP) prediction that organisms with the faculty of language cognitively process languagelike systems in a qualitatively distinct manner. I first discuss “languagelike” as a technical term defined by recursion criteria. …”
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    Languagelike-Specificity of Event-Related Potentials From a Minimalist Program Perspective
  17. 5017
    “…However, designing robust and reliable nonlinearity remains a challenge, in part, due to the difficulty in describing the behaviour of nonlinear systems in an intuitive manner. Here, we present an approach that overcomes this difficulty by constructing an effectively one-dimensional system that can be tuned to produce bespoke nonlinear responses in a systematic and understandable manner. …”
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    Bespoke extensional elasticity through helical lattice systems
  18. 5018
    “…Methylprednisolone decreased proliferation and increased apoptosis of NK cells in a significant manner. After seven days, a reduction of viable NK cells was seen for all three immunosuppressants, which was significant for MPA only. …”
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    Distinct Effects of Immunosuppressive Drugs on the Anti-Aspergillus Activity of Human Natural Killer Cells
  19. 5019
    “…We concluded that though most of EW effects were immediate, such nutritional change in the infancy might affect part of gastric digestive functions in a permanent manner, as some markers were kept unbalanced in the adulthood.…”
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    Immediate and Late Effects of Early Weaning on Rat Gastric Cell Differentiation
  20. 5020
    “…The extract (1.25–12.5 μg/mL) increased cytokine secretion in a concentration-dependent manner, but an increase in cytotoxicity was also noted. …”
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    Modulatory Effect of Chelidonium majus Extract and Its Alkaloids on LPS-Stimulated Cytokine Secretion in Human Neutrophils
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