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  1. 5421
    “…This study is the first to demonstrate in vivo that phosphorylation of a transactivation domain in a nuclear steroid receptor modulates its activity in a tissue-dependent manner.…”
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    SUN-744 Phosphorylation Site S122 in Estrogen Receptor α Has a Tissue-Dependent Role in Female Mice
  2. 5422
    “…It protects not only NMR cells, but also mouse and human cells from stress-induced cell-cycle arrest and cell death in a polymer length-dependent manner. The cytoprotective effect is dependent on the major HA-receptor, CD44. …”
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    Naked mole-rat very-high-molecular-mass hyaluronan exhibits superior cytoprotective properties
  3. 5423
    “…This paper suggests an additional approach where XRF scanning is performed in a sparse way by skipping specific points or by varying dynamically acquisition time or other scan settings in a conditional manner. This paves the way for Compressive Sensing in XRF scans where data are acquired in a reduced manner allowing for challenging experiments, currently not feasible with the traditional scanning strategies. …”
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    Compressive Sensing for Dynamic XRF Scanning
  4. 5424
    “…In its severe manifestation, coronavirus disease 2019 (COVID-19) compromises oxygenation in a manner that is refractory to maximal conventional support and requires escalation to extracorporeal membrane oxygenation (ECMO). …”
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    Bivalirudin for Maintenance Anticoagulation During Venovenous Extracorporeal Membrane Oxygenation for COVID-19
  5. 5425
    “…This paper introduce an efficient algorithm (SpiFoG) to train multilayer feed forward SNN in supervised manner that uses elitist floating point genetic algorithm with hybrid crossover. …”
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    SpiFoG: an efficient supervised learning algorithm for the network of spiking neurons
  6. 5426
    “…R-ZnO nanoparticles can inhibit L. major growth in a dose-dependent manner under in vitro conditions CONCLUSION: A simple, low-cost feasible and eco-friendly procedure was developed for biosynthesis of R-ZnO nanoparticles using natural bioresource that can inhibit human parasite cells growth in a dose-dependent manner under in vitro conditions…”
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    Greener synthesis of Rod Shaped Zinc Oxide Nanoparticles using Lilium ledebourii tuber and evaluation of their Leishmanicidal activity
  7. 5427
    “…Disarib induced cancer cell death in a BCL2 dependent manner in different cancer cell lines and mouse tumor models when it was administered intraperitoneally. …”
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    Acute toxicity analysis of Disarib, an inhibitor of BCL2
  8. 5428
    “…Manipulations of TORC1 activity increase or decrease ATFS-1 activity in a manner that correlates with protein synthesis. Lastly, expression of mitochondrial-targeted GFP is sufficient to expand the muscle cell mitochondrial network in an ATFS-1-dependent manner. …”
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    UPR(mt) scales mitochondrial network expansion with protein synthesis via mitochondrial import in Caenorhabditis elegans
  9. 5429
    “…In addition to this function of lipids, TM regions of proteins bind to lipids in a very specific manner, but the function of these TM region-lipid interactions is mostly unknown. …”
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    Direct Regulation of the T Cell Antigen Receptor's Activity by Cholesterol
  10. 5430
    “…Staging the severity of adiposity-related disease in a “complication-centric” manner (HTN, dyslipidemia, metabolic syndrome, T2DM, obstructive sleep apnea, etc.) among different ethnic groups in patients with COVID-19 should help predict the adverse risk of adiposity on patient health in a pragmatic and actionable manner during this pandemic.…”
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    Covid-19 & Obesity: Beyond Bmi
  11. 5431
    “…In the presence of patient serum, γδ2 T cells phagocytosed and degraded opsonized iRBCs in a CD16-dependent manner, decreasing parasite multiplication. Thus, γδ2 T cells have two ways to control blood stage malaria – γδT cell antigen receptor (TCR)-mediated degranulation and phagocytosis of antibody-coated iRBCs.…”
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    γδ T cells suppress Plasmodium falciparum blood stage infection by direct killing and phagocytosis
  12. 5432
    “…However, these distinct features do not translate into different capacities to control a respiratory vaccinia virus challenge in an antigen-specific manner, although differential activation mechanisms are utilized. …”
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    Influenza- and MCMV-induced memory CD8 T cells control respiratory vaccinia virus infection despite residence in distinct anatomical niches
  13. 5433
    “…CircRNAs are highly stable and usually expressed in a tissue- or cell type-specific manner. Therefore, they are currently being explored as potential therapeutic targets. …”
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    Targeting circular RNAs as a therapeutic approach: current strategies and challenges
  14. 5434
    “…Quorum sensing peptides (QSPs) are bacterial peptides produced by Gram-positive bacteria to communicate with their peers in a cell-density dependent manner. These peptides do not only act as interbacterial communication signals, but can also have effects on the host. …”
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    PapRIV, a BV-2 microglial cell activating quorum sensing peptide
  15. 5435
    “…The MTT assay results showed that PPa extract significantly inhibited the proliferation of HL‐60 cells in a dose‐dependent manner and affected cell morphology, causing cell shrinkage and the formation of debris. …”
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    Pogostemon cablin extract as an anticancer agent on human acute myeloid leukemia
  16. 5436
    “…The in vivo and in vitro assays of humoral and cellular response to drugs were carried out in a longitudinal manner throughout the DD cycles. We observed a progressive decrease of the pre-procedure ADA titer with negativization during the DD cycles in both patients. …”
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    Drug-specific Treg cells are induced during desensitization procedure for rituximab and tocilizumab in patients with anaphylaxis
  17. 5437
    “…KO rat pups showed high neonatal mortality but not in a sex‐dependent manner and did not show altered hypoxic or hypercapnic ventilatory chemoreflexes. …”
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    Mortality and ventilatory effects of central serotonin deficiency during postnatal development depend on age but not sex
  18. 5438
    “…Not all epidemics fit this pattern in a consistent manner, with some occurring later or in an irregular manner. …”
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    Defining the seasonality of respiratory syncytial virus around the world: National and subnational surveillance data from 12 countries
  19. 5439
    “…Just as epigenetics is responsible for the imprinting of environmental conditions on a genetic level, epitranscriptomics follows the same principle at the RNA level, but in a more dynamic and sensitive manner. Nevertheless, its impact in the field of cardiovascular disease (CVD) remains largely unexplored. …”
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    Epitranscriptomics of cardiovascular diseases (Review)
  20. 5440
    “…In contrast, DUSP1 responds in the canonical manner and its transcriptional activity is promoted by acetylation. …”
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    Complexities in the role of acetylation dynamics in modifying inducible gene activation parameters
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