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5441por Lövenich, Lukas, Dreissen, Georg, Hoffmann, Christina, Konrad, Jens, Springer, Ronald, Höhfeld, Jörg, Merkel, Rudolf, Hoffmann, Bernd“…The strength of the observed delay depends on stable adhesion structures and stress fiber formation in a Ras homologue family member A (RhoA)-dependent manner.…”
Publicado 2021
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5442por Abdel-Moneim, Abdel-Moneim Eid, El-Saadony, Mohamed T., Shehata, Abdelrazeq M., Saad, Ahmed M., Aldhumri, Sami Ali, Ouda, Sahar M, Mesalam, Noura M.“…Besides, Spirulina extracts significantly scavenged ABTS and DPPH radicals in a dose-dependent manner. The methanolic extract had higher total phenolic content, antimicrobial activity, and antioxidant activity than other extracts. …”
Publicado 2022
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5443por Zheng, Xin, Xiao, Jun, Jiang, Qi, Zheng, Lingming, Liu, Chang, Dong, Chen, Zheng, Yuxiao, Ni, Peili, Zhang, Chi, Zhang, Fang, Zhong, Ruiyue, Ding, Huihua, Wang, Qiong, Qiu, Ying, Gao, Minxia, Ding, Jianping, Shen, Nan, Wei, Bin, Wang, Hongyan“…Overexpression of AKT2 kinase‐inactive or IRF3‐T207A mutants in zebrafish supports that AKT2 negatively regulates I‐IFN production and antiviral response in a kinase‐dependent manner. This negative role of AKT2 in IRF3‐induced I‐IFN production suggests that AKT2 may be therapeutically targeted to differentially regulate antiviral infection and SLE.…”
Publicado 2022
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5444por Lehne, Franziska, Pokrant, Thomas, Parbin, Sabnam, Salinas, Gabriela, Großhans, Jörg, Rust, Katja, Faix, Jan, Bogdan, Sven“…Contrary to previous assumptions, TIRF-analyses unambiguously demonstrate that EFhD2/Swip-1 proteins efficiently cross-link actin filaments in a calcium-dependent manner. Using a single-cell wounding model, we show that EFhD2/Swip-1 promotes wound closure in a calcium-dependent manner. …”
Publicado 2022
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5445por Hobson, Claire Amaris, Vigué, Lucile, Magnan, Mélanie, Chassaing, Benoit, Naimi, Sabrine, Gachet, Benoit, Claraz, Pauline, Storme, Thomas, Bonacorsi, Stephane, Tenaillon, Olivier, Birgy, André“…Daunorubicin was associated with significant changes in alpha- and beta-diversity as well as in the ratio of Firmicutes/Bacteroidetes in a donor-dependent manner. The impact of hydroxycarbamide on microbiota composition was not significant. …”
Publicado 2022
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5446por Yamamoto, Takayoshi, Kambayashi, Yuta, Otsuka, Yuta, Afouda, Boni A, Giuraniuc, Claudiu, Michiue, Tatsuo, Hoppler, Stefan“…Secreted molecules called morphogens govern tissue patterning in a concentration-dependent manner. However, it is still unclear how reproducible patterning can be achieved with diffusing molecules, especially when that patterning concerns differentiation of thin tissues. …”
Publicado 2022
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5447por Kiryu‐Seo, Sumiko, Matsushita, Reika, Tashiro, Yoshitaka, Yoshimura, Takeshi, Iguchi, Yohei, Katsuno, Masahisa, Takahashi, Ryosuke, Kiyama, Hiroshi“…Here, we develop a unique mouse model using a regulatory element of the activating transcription factor (Atf3) gene to label mitochondria in a damage‐induced manner while simultaneously genetically disrupting the proteasome. …”
Publicado 2022
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5448“…This is frequently done in a whole‐brain voxel‐wise manner, in which a population of patients and healthy controls are registered to a common co‐ordinate space and a statistical test is performed on the distribution of image intensities for each location. …”
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5449por Prochazka, Laura, Michaels, Yale S, Lau, Charles, Jones, Ross D, Siu, Mona, Yin, Ting, Wu, Diana, Jang, Esther, Vázquez‐Cantú, Mercedes, Gilbert, Penney M, Kaul, Himanshu, Benenson, Yaakov, Zandstra, Peter W“…This circuit was applied to regulate the secretion of endogenous BMP4 in a state‐specific and fine‐tuned manner to control the composition of differentiating hPSCs. …”
Publicado 2022
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5450Diagnosis of Scoliosis Using Chest Radiographs with a Semi-Supervised Generative Adversarial NetworkPublicado 2022“…Our proposed method used training GAN with mild to severe scoliosis only in a semi-supervised manner, as an upstream task to learn scoliosis representations and a downstream task to perform simple classification for differentiating between normal and scoliosis states sensitively. …”
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5451por McKay, Andrew, Costa, Emma K, Chen, Jingxun, Hu, Chi-Kuo, Chen, Xiaoshan, Bedbrook, Claire N, Khondker, Rishad C, Thielvoldt, Mike, Priya Singh, Param, Wyss-Coray, Tony, Brunet, Anne“…The ability to precisely control food delivery in the killifish opens new areas to assess lifespan and cognitive behavior dynamics and to screen for dietary interventions and drugs in a scalable manner previously impossible with traditional vertebrate model organisms.…”
Publicado 2022
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5452por Weydert, C., Frixione, S., Herquet, M., Klasen, M., Laenen, E., Plehn, T., Stavenga, G., White, C.D.“…The process is defined in a model independent manner for wide applicability, and can be used if the charged Higgs boson mass is either greater or less than the mass of the top quark. …”
Publicado 2009
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5453“…In particular, we find a characteristic bound-state effect on the (bW^+)-(\bar{b}W^-) double-invariant-mass distribution, which is deformed to the lower invariant-mass side in a correlated manner.…”
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5454por Basdevant, Jean-Louis“…The author’s style is clear and stimulating, in the manner of a brisk classroom lecture that students can follow with ease and enjoyment. …”
Publicado 2016
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5455“…Our approach is systematic in the sense that we perform the analysis in a manner which minimizes apriori theoretical assumptions as to the nature of the scalar particle. …”
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5456por Stowisek, J“…The set-up of the SCADA system in a redundant, distributed and scattered manner in order to guarantee high dependability and the possibility of doing data exchange with external PVSS II systems is a central issue of this work. …”
Publicado 2001
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5457por Tang, Bozeng, Yan, Xia, Ryder, Lauren S., Bautista, Mark Jave A., Cruz-Mireles, Neftaly, Soanes, Darren M., Molinari, Camilla, Foster, Andrew J., Talbot, Nicholas J.“…How effector gene expression is regulated in such a precise manner during invasive growth by M. oryzae is not known. …”
Publicado 2023
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5458Poly(amidoamine) Dendrimer/Camptothecin Complex: From Synthesis to In Vitro Cancer Cell Line Studiespor Oledzka, Ewa, Paśnik, Klaudia, Domańska, Izabela, Zielińska-Pisklak, Monika, Piotrowska, Urszula, Sobczak, Marcin, Szeleszczuk, Łukasz, Laskowska, Anna“…The in vitro drug release study revealed that the drug was released in a slow and controlled manner in acidic and physiological conditions and that more than 80% of the drug was released after 168 h of incubation. …”
Publicado 2023
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5459por Bajo-Santos, Cristina, Priedols, Miks, Kaukis, Pauls, Paidere, Gunita, Gerulis-Bergmanis, Romualds, Mozolevskis, Gatis, Abols, Arturs, Rimsa, Roberts“…Our aim was to design a new cyclic olefin copolymer–off-stoichiometry thiol-ene (COC–OSTE) asymmetric flow field fractionation microfluidic device that could isolate EV from high-volume samples in a simple and efficient manner. We tested the device with large volumes of urine and conditioned cell media samples, and compared it with the two most commonly used EV isolation methods. …”
Publicado 2023
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5460“…However, previous methods usually employ a single deep learning model to extract temporal or spatial features, or extract spatial features first and then temporal features in a serial manner. These methods usually have the problem of insufficient extraction of spatio-temporal features of the IoV, which affects the performance of intrusion detection and leads to a high false-positive rate. …”
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