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5561“…Actin filaments bind purified Drp1 and increase GTPase activity in a manner that is synergistic with the mitochondrial protein Mff, suggesting a role for direct Drp1/actin interaction. …”
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5562“…Moreover, self-pupylation of PafA is involved in the regulation of its stability in vivo in a proteasome-dependent manner, suggesting that PafA self-pupylation functions as a mechanism in the auto-regulation of the Pup-proteasome system.…”
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5563“…A large body of research has established that, under relatively simple task conditions, human observers integrate uncertain sensory information with learned prior knowledge in an approximately Bayes-optimal manner. However, in many natural tasks, observers must perform this sensory-plus-prior integration when the underlying generative model of the environment consists of multiple causes. …”
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5564“…Conversely, mimicry of the wrong person is costly because individuals will internalize “bad habits,” including emotional reactions and mannerisms indicating wrong group membership. This pattern of mimicry, in turn, means that observed mimicry is an honest signal of group affiliation. …”
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5565“…This ontology supports the capture of voltage-gated ion channel electrophysiological data from the literature in a structured manner and thus enables other applications such as querying and reasoning tools. …”
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5566por Lee, Jae Won, Mok, Hyuck Jun, Lee, Dae-Young, Park, Seung Cheol, Ban, Myeong Soon, Choi, Jehun, Park, Chun Geon, Ahn, Young-Sup, Kim, Kwang Pyo, Kim, Hyung Don“…LPS treatment increased nitric oxide production and secretion of pro-inflammatory cytokines, such as tumor necrosis factor-α and interleukin-6, in a concentration-dependent manner. In total, 79 eicosanoids were identified in the cells. …”
Publicado 2016
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5567“…Mitochondrial (mtDNA) and nuclear genes have to operate in a coordinated manner to maintain organismal function, and the regulation of this homeostasis presents a substantial source of potential epistatic (G × G) interactions. …”
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5568por Tiferet-Dweck, Chen, Hensel, Michael, Kirschbaum, Clemens, Tzelgov, Joseph, Friedman, Alon, Salti, Moti“…Stress and perceptual load affect selective attention in a paradoxical manner. They can facilitate selectivity or disrupt it. …”
Publicado 2016
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5569por Bohrer, Annerose, Heinze, Cornelia, Höppner, Heidi, Behrend, Ronja, Czakert, Judith, Hitzblech, Tanja, Kaufmann, Ina, Maaz, Asja, Räbiger, Jutta, Peters, Harm“…Aim: The Berlin project "Interprofessional teaching and learning in medicine, occupational therapy, physiotherapy and nursing" (INTER-M-E-P-P) pursues the goal of developing and testing interprofessional courses in an exemplary manner, and then implement these into their regular study programs. …”
Publicado 2016
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5570por Kalra, Sanjay“…An observational study was conducted at a single center, in the real world setting, on six persons who either switched to IDeg or IDegAsp a month before Ramadan or changed time of administration of IDegAsp at the onset of Ramadan, to keep the fast in a safe manner. Subjects were kept under regular monitoring and surveillance before, during, and after Ramadan, and counseled in an opposite manner. …”
Publicado 2016
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5571“…ESyts bind phospholipids in a Ca(2+)-dependent manner via their C2-domains, are localized to ER-plasma membrane contact sites, and may catalyze lipid exchange between the plasma membrane and the ER via their SMP-domains. …”
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5572“…We found that Sch B inhibited the viability and proliferation of CCA cells in a dose- and time-dependent manner as assessed by MTT and colony formation assays. …”
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5573por Schröder, Lennard, Richter, Dagmar Ulrike, Piechulla, Birgit, Chrobak, Mareike, Kuhn, Christina, Schulze, Sandra, Abarzua, Sybille, Jeschke, Udo, Weissenbacher, Tobias“…Estradiol production was inhibited in all cells in a concentration-dependent manner. EFE upregulated ERα in JEG-3 cell lines. In MCF7 cells, a significant ERα downregulation and PR upregulation were observed. …”
Publicado 2016
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5574por Testa, Claudia, Pultrone, Cristian, Manners, David Neil, Schiavina, Riccardo, Lodi, RaffaeleEnlace del recurso
Publicado 2016
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5575por Wang, Yuqiong, Jin, Gang, Li, Quanjiang, Wang, Zhiping, Hu, Weimin, Li, Ping, Li, Shude, Wu, Hongyu, Kong, Xiangyu, Gao, Jun, Li, Zhaoshen“…Hedgehog(HH) pathway is found to be activated through a manner of canonical, or the non-canonical HH pathways. …”
Publicado 2016
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5576“…Together with the GPI-anchored glycoprotein Reck, this adhesion GPCR (aGPCR) stimulates Wnt7-dependent Wnt/β-catenin signaling to promote brain vascular invasion in an endothelial cell-autonomous manner. Adgra2 and Reck have been proposed to assemble a receptor complex at the plasma membrane, but the molecular modalities of their functional synergy remain to be investigated. …”
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5577“…The in vivo corneal epithelial disruption, corneal edema/opacity and neovascularization, which were in accordance with the results of the H/E staining and peaked at Day 7, were observed in a dose-dependent manner in the BAC-treated mice, with more severe signs in the C57BL/6 mice than the BALB/c mice. …”
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5578“…Surface acoustic waves generated from piezoelectric substrates were directly coupled into rose leaves, thereby causing water to rapidly evaporate in a highly localized manner only at the site in contact with the actuator. …”
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5579“…The WUSCHEL homeobox transcription factor is required to specify stem-cell identity at the shoot apical meristem and its ectopic expression is sufficient to induce de novo shoot meristem formation. Yet, the manner by which WUS promotes stem-cell fate is not yet fully understood. …”
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5580“…MNPs produced reactive oxygen species (ROS) and declined in mitochondrial membrane potential in the SH-SY5Y cell in dose and duration dependent manner. Moreover, lipid peroxide (LPO), superoxide dismutase (SOD), and catalase (CAT) activities were increased and glutathione was reduced in dose and time dependent manner. …”
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