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5601“…The myogenic differentiation was also enhanced in a treatment time-dependent manner, as evidenced by an increase in myotube size and fusion index. …”
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5602por Li, Guorui, Chen, Haobo, Peng, Sancheng, Li, Xinguang, Wang, Cong, Yu, Shui, Yin, Pengfei“…Furthermore, we also design a distributed cluster-constructing algorithm to construct the clusters around the virtual CHs in a distributed manner. The experimental results show that the proposed method not only reduces the total energy consumption and prolongs the network lifetime, but also effectively balances the distribution of energy consumption among CHs. …”
Publicado 2018
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5603por Lian, Wenwen, Fang, Jiansong, Xu, Lvjie, Zhou, Wei, Kang, De, Xiong, Wandi, Jia, Hao, Liu, Ai-Lin, Du, Guan-Hua“…Further, DL0410 inhibited the AChE activity and increased acetylcholine (ACh) levels in a dose-dependent manner, and interacted with the active site of AChE in a similar manner as donepezil. …”
Publicado 2017
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5604“…In this situation, peptide release will presumably be tightly coupled to the manner in which a network is activated. For example, data obtained in early studies suggest that peptide release will be potentiated when behavior is executed rapidly and intervals between periods of neural activity are relatively short. …”
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5605“…Biochanin A decreased cell viability in a time-dependent and dose-dependent manner and suppressed colony formation in A549 and 95D cells. …”
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5606“…As for the drain-side n-p-n-arranged type with discrete-anode manners, transmission–line–pulse (TLP) testing results showed that the ESD ability (I(t2) value) was slightly upgraded. …”
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5607“…Our behavioral findings showed a gradual increase in cognitive load from CIT1 to CIT3 followed by an abrupt increase between CIT4 (i.e., listening to two concurrent melodic contours in an alternating manner and identifying the direction of the target contour, p < 0.001) and CIT5 (i.e., listening to two concurrent melodic contours in a divided manner and identifying the directions of both contours, p < 0.001). …”
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5608por Le Sage, Valerie, Nanni, Adalena V., Bhagwat, Amar R., Snyder, Dan J., Cooper, Vaughn S., Lakdawala, Seema S., Lee, Nara“…We show that, similar to H1N1 strains, NP binds vRNA in a non-uniform and non-random manner. Each viral gene segment has a unique NP binding profile with areas that are enriched for NP association as well as free of NP-binding. …”
Publicado 2018
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5609“…This is derived by combining the eye-tracking gaze maps of medical experts in a novel manner based on a set of rules. This strategy requires scrutiny of images in a manner which is consistent with spatial preferences found in human perception in general and in the domain of fundus images in particular. …”
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5610por Yang, Jing-Iong, Yeh, Chi-Chen, Lee, Jin-Ching, Yi, Szu-Cheng, Huang, Hurng-Wern, Tseng, Chao-Neng, Chang, Hsueh-Wei“…In a cell-free assay, the extract exhibited 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical scavenging activity that significantly reduced H(2)O(2)-induced plasmid DNA breaks in a dose-response manner (P < 0.001). The AEGT also suppressed H(2)O(2)-induced oxidative DNA damage in H1299 cells by reducing the percentage of damaged DNA in a dose-response manner (P < 0.001) as measured by a modified alkaline comet-nuclear extract (comet-NE) assay. …”
Publicado 2012
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5611por Jou, Yu-Jen, Hua, Chun-Hung, Lin, Chen-Sheng, Wang, Ching-Ying, Wan, Lei, Lin, Ying-Ju, Huang, Su-Hua, Lin, Cheng-Wen“…Cell cycle analysis with PI staining showed γ-bisabolene elevating the sub-G1 fractions in a time-dependent manner. In addition, annexin V-FITC/PI staining showed γ-bisabolene significantly triggering early (annexin-V positive/PI negative) and late (annexin-V positive/PI positive) apoptosis in dose-dependent manners. γ-Bisabolene induced caspase 3/8/9 activation, intracellular ROS increase, and mitochondrial membrane potential decrease in apoptosis of human neuro-blastoma cells. …”
Publicado 2016
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5612“…The α-melanocyte-stimulating hormone (α-MSH)-induced melanin production was significantly inhibited by K7G and tilianin in a dose-dependent manner. The effects of these compounds on the signaling pathway of melanogenesis were examined. …”
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5613“…The reputation threshold was theoretically analyzed to minimize the probability of choosing the sensing manner with worse performance. Simulations were carried out to verify the viability and the efficiency of the proposed algorithm.…”
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5614por Kamei, Miho, Otani, Yukie, Hayashi, Hidenori, Nakamura, Tadaho, Yanai, Kazuhiko, Furuta, Kazuyuki, Tanaka, Satoshi“…These findings suggest that pyrilamine, diphenhydramine, JNJ7777120, and thioperamide can suppress IFN-γ production in activated splenocytes in a histamine-independent manner.…”
Publicado 2018
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5615por Tsai, Ching-Chung, Chang, Li-Ching, Huang, Shih-Che, Tey, Shu-Leei, Hsu, Wen-Li, Su, Yu-Tsun, Liu, Ching-Wen, Tsai, Tong-Rong“…Next, SM extracts significantly induce extracellular Ca(2+) entry into primary LES cells in addition to intracellular Ca(2+) release and in a dose-response manner. Confocal fluorescence microscopy showed that the SM extracts consistently induced significant extracellular Ca(2+)influx into primary LES cells in a time-dependent manner. …”
Publicado 2015
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5616“…In mammalian cells, transcribed enhancers (TrEns) play important roles in the initiation of gene expression and maintenance of gene expression levels in a spatiotemporal manner. One of the most challenging questions is how the genomic characteristics of enhancers relate to enhancer activities. …”
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5617por Hohmann, Tim, Feese, Kerstin, Ghadban, Chalid, Dehghani, Faramarz, Grabiec, Urszula“…Cannabinoids induced changes in cell motility, morphology and actin organization in a receptor and cell line dependent manner. No significant changes were observed in the analyzed signaling molecules. …”
Publicado 2019
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5618por Ozawa, Kentaro, Taomori, Hirotaka, Hoshida, Masayuki, Kunita, Ituki, Sakurazawa, Sigeru, Honda, Hajime“…We found that actin filaments when at the intermediate concentrations ranging from 0.1 to 1.0 mg/mL, formed winding belt-like patterns and moved in a two-directional manner along the belts. These patterns were spread over a millimeter range and found to have bulged on the glass in a three-dimensional manner. …”
Publicado 2019
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5619por Sadaba, Naroa, Salsamendi, Maitane, Casado, Nerea, Zuza, Ester, Muñoz, Jone, Sarasua, Jose-Ramon, Mecerreyes, David, Mantione, Daniele, Detrembleur, Christophe, Sardon, Haritz“…There is a great interest in incorporating catechol moieties into polymers in a controlled manner due to their interesting properties, such as the promotion of adhesion, redox activity or bioactivity. …”
Publicado 2018
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5620por Kim, Wonkyong, Choi, Jee Soo, Kim, Daun, Shin, Doohang, Suk, Shinae, Lee, Younghoon“…The sRNA DsrA activates translation of the rpoS mRNA in an Hfq-dependent manner, but this activation ability was found to partially bypass Hfq when DsrA is overproduced. …”
Publicado 2019
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