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6981por Razi, Mazdak, Sadrkhanloo, Rajab-Ali, Malekinejad, Hassan, Sarafzadeh-Rezaei, Farshid“…Serum TAOC and TTM levels reduced in a time-dependent manner. Right testes varicocele-induced rats showed remarkably less damaged profile for all investigated parameters compared to the left testes varicocele. …”
Publicado 2011
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6982por Akagi, Aya, Fukushima, Setsuko, Okada, Kazunori, Jiang, Chang-Jie, Yoshida, Riichiro, Nakayama, Akira, Shimono, Masaki, Sugano, Shoji, Yamane, Hisakazu, Takatsuji, Hiroshi“…The DP biosynthetic genes were barely upregulated in BTH-treated rice plants, but were induced rapidly after M. oryzae infection in a WRKY45-dependent manner. These results indicate that the DP biosynthetic genes were primed by BTH through WRKY45. …”
Publicado 2014
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6983“…MicroRNAs (miRNAs) are short noncoding RNAs that regulate the expression of their targets in a sequence-dependent manner. For protein-coding transcripts, miRNAs regulate expression levels through binding sites in either the 3′ untranslated region (3′ UTR) or the amino acid coding sequence (CDS) of the targeted messenger RNA (mRNA). …”
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6984“…AIM: To seek accurate and credible correlation manner between gender, age, and obesity; and the severity of obstructive sleep apnea (OSA) in large-scale population. …”
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6985por Kianianmomeni, Arash“…BACKGROUND: The multicellular green alga Volvox carteri makes use of none less than 13 photoreceptors, which are mostly expressed in a cell-type specific manner. This gives reason to believe that trasncriptome pattern of each cell type could change differentially in response to environmental light. …”
Publicado 2014
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6986por Kong, Qingran, Hai, Tang, Ma, Jing, Huang, Tianqing, Jiang, Dandan, Xie, Bingteng, Wu, Meiling, Wang, Jiaqiang, Song, Yuran, Wang, Ying, He, Yilong, Sun, Jialu, Hu, Kui, Guo, Runfa, Wang, Liu, Zhou, Qi, Mu, Yanshuang, Liu, Zhonghua“…And, muscle-specific promoter MyoP was activated strictly in muscle of the pRosa26 targeted pigs, indicating Rosa26 locus supports tissue-specific promoter driving transgene expression in its own manner. The study provided further demonstration on biomedical and agricultural applications of porcine Rosa26 promoter and locus.…”
Publicado 2014
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6987“…CONCLUSION: It is possible to successfully and reliably inject local anesthesia in a minimally painful manner for cleft lip and nasal repair in the fully grown cleft patient.…”
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6988por Kim, Seaho, Kim, Dong Hwan, Lee, Sun Hwa, Kim, Min Jeong, Yoon, Jeong-Hyun, Chung, Hae Young, Na, Chun Soo, Kim, Nam Deuk“…RESULTS: The cytotoxic results from MTT assays indicated that urushiol inhibited human gastric cancer cell growth in a dose-dependent manner, with IC50 values of approximately 15 and 20 μg/ml on MKN-45 and MKN-28 cells, respectively. …”
Publicado 2013
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6989por Long, Jian-Ting, Cheang, Tuck-yun, Zhuo, Shu-Yu, Zeng, Rui-Fang, Dai, Qiang-Sheng, Li, He-Ping, Fang, Shi“…RESULTS: The EGNP released DOX in a sustained manner and effectively internalized in EGFR overexpressing A549 and H226 lung cancer cells via a receptor-mediated endocytosis. …”
Publicado 2014
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6990Resveratrol and curcumin enhance pancreatic β-cell function by inhibiting phosphodiesterase activity“…Additionally, treating β-cell lines and human islets with these polyphenols led to increased intracellular cAMP levels in a manner similar to 3-isobutyl-1-methylxanthine, a classic PDE inhibitor. …”
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6991por Vaicik, Marcella K., Thyboll Kortesmaa, Jill, Movérare-Skrtic, Sofia, Kortesmaa, Jarkko, Soininen, Raija, Bergström, Göran, Ohlsson, Claes, Chong, Li Yen, Rozell, Björn, Emont, Margo, Cohen, Ronald N., Brey, Eric M., Tryggvason, Karl“…Interestingly, the mice had decreased adipose tissue mass and altered lipogenesis in a depot-specific manner. In particular, epididymal adipose tissue mass was specifically decreased in knock-out mice, and there was also a defect in lipogenesis in this depot as well. …”
Publicado 2014
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6992por Wallkamm, Veronika, Dörlich, Rene, Rahm, Karolin, Klessing, Tina, Nienhaus, Gerd Ulrich, Wedlich, Doris, Gradl, Dietmar“…This construct activates non-canonical Wnt pathways in an endocytosis dependent manner and is capable of compensating for the loss of endogenous Xwnt5A in Xenopus embryos. …”
Publicado 2014
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6993“…Our data indicate that ERRγ is not required for skeletal development but is a sex-dependent negative regulator of postnatal bone formation, acting in a RUNX2- and apparently differentiation stage-dependent manner.…”
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6994“…When not neglected in signal transduction models, these differences are accounted for in a static manner, by assuming randomly distributed initial protein levels. …”
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6995por Månsson, Cecilia, Arosio, Paolo, Hussein, Rasha, Kampinga, Harm H., Hashem, Reem M., Boelens, Wilbert C., Dobson, Christopher M., Knowles, Tuomas P. J., Linse, Sara, Emanuelsson, Cecilia“…We show in the present study that DNAJB6 also inhibits amyloid formation by an even more aggregation-prone peptide (the amyloid-beta peptide, Aβ42, implicated in Alzheimer disease) in a highly efficient manner. By monitoring fibril formation using Thioflavin T fluorescence and far-UV CD spectroscopy, we have found that the aggregation of Aβ42 is retarded by DNAJB6 in a concentration-dependent manner, extending to very low sub-stoichiometric molar ratios of chaperone to peptide. …”
Publicado 2014
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6996por Deivasigamani, Senthilkumar, Verma, Hemant Kumar, Ueda, Ryu, Ratnaparkhi, Anuradha, Ratnaparkhi, Girish S.“…One such mutation, P56S, was identified in human VAPB that behaves in a dominant negative manner, sequestering wild type protein into cytoplasmic inclusions. …”
Publicado 2014
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6997por Chillón, Isabel, Molina-Sánchez, María Dolores, Fedorova, Olga, García-Rodríguez, Fernando Manuel, Martínez-Abarca, Francisco, Toro, Nicolás“…Group II introns are catalytic RNAs that are excised from their precursors in a protein-dependent manner in vivo. Certain group II introns can also react in a protein-independent manner under nonphysiological conditions in vitro. …”
Publicado 2014
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6998“…Whether upon activation p53 binds to its genomic targets in a cell type and stress type dependent manner is still an open question. Here we show that the p53 binding to the human genome is selective and cell context-dependent. …”
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6999por Qi, Bing, Cong, Qian, Li, Ping, Ma, Gang, Guo, Xizhi, Yeh, James, Xie, Min, Schneider, Michael D., Liu, Huijuan, Li, Baojie“…These findings indicate that Tak1 functions in osteoclastogenesis in a cell-autonomous manner and in osteoblastogenesis and chondrogenesis in non-cell-autonomous manners.…”
Publicado 2014
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7000“…CONCLUSION: Incorporating information from incidence assays in the manner proposed has the potential to improve estimates. …”
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