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101341“…Currently computer vision technologies have shown great potential to automate this task effectively in a low-end manner. In particular, counting wheat spikes is a typical visual counting problem, which is substantially studied under the name of object counting in Computer Vision. …”
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101342“…Data showed that irradiated conditioned media from MCF-7 cells, when incubated with HUVECs, significantly enhanced the cell migration and wound healing rate of HUVECs in a dose-dependent manner (P < 0.05). The mRNA levels of VEGFR-2, HSP-70, Ang-2, and Ang-1 were dose-dependently enhanced in HUVECs incubated with irradiated conditioned media (P < 0.05). …”
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101343por Chen, Zhuming, Zhong, Huan, Wei, Jinsong, Lin, Sien, Zong, Zhixian, Gong, Fan, Huang, Xinqia, Sun, Jinhui, Li, Peng, Lin, Hao, Wei, Bo, Chu, Jiaqi“…Furthermore, the NLRP3, Nrf2, HO-1, IL-1β, and IL-18 expression in LPS-treated SW982 cells was increased in a dose-dependent manner. As expected, the expression of NLRP3 was upregulated, and the expression of IL-1β and IL-18 was downregulated after Nrf2 silencing. …”
Publicado 2019
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101344por Ye, Yingze, Jin, Tong, Zhang, Xu, Zeng, Zhi, Ye, Baixin, Wang, Jinchen, Zhong, Yi, Xiong, Xiaoxing, Gu, Lijuan“…Furthermore, we verified the inhibitory effect of meisoindigo on TLR4/NF-κB signaling pathway, and found that meisoindigo treatment could significantly suppressed the expression of TLR4/NF-κB pathway-associated proteins in a dose-dependent manner, meanwhile, which resulted in downregulation of HMGB1 and IL-1β. …”
Publicado 2019
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101345por Günther, Thomas, Fröhlich, Jacqueline, Herrde, Christina, Ohno, Shinji, Burkhardt, Lia, Adler, Heiko, Grundhoff, Adam“…Statistical analyses of ChIP-seq data from in vitro infected cells as well as in vivo latency reservoirs furthermore suggest that, whereas KSHV rapidly attracts PRCs in a genome-wide manner, H3K27-me3 acquisition by MHV-68 genomes may require spreading from initial seed sites to which PRC are recruited as the result of an inefficient or stochastic recruitment, and that immune pressure may be needed to select for latency pools harboring PRC-silenced episomes in vivo. …”
Publicado 2019
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101346por Manning, Warren J.“…It takes a village to run a journal and I thank our very dedicated Associate Editors, Guest Editors, Reviewers for their efforts to ensure that the review process occurs in a timely and responsible manner. These efforts have allowed the JCMR to continue as the premier journal of our field. …”
Publicado 2019
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101347“…In order to investigate the public’s ability to recognise such signs of equine distress, members of equestrian Facebook groups were asked to view and comment on six videos; these videos were selected by the authors on account of their portrayal of horses behaving in a manner suggestive of negative affect. For comparison, responses were also obtained from six equine behaviourists, who identified behaviours suggestive of varying degrees of distress. …”
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101348por Martin, Pauline, Wagh, Vilas, Reis, Surya A., Erdin, Serkan, Beauchamp, Roberta L., Shaikh, Ghalib, Talkowski, Michael, Thiele, Elizabeth, Sheridan, Steven D., Haggarty, Stephen J., Ramesh, Vijaya“…TSC1-Het and Null NPCs also revealed enhanced proliferation and altered neurite outgrowth in a genotype-dependent manner, which was not reversed by rapamycin. Transcriptome analyses of TSC1-NPCs revealed differentially expressed genes that display a genotype-dependent linear response, i.e., genes upregulated/downregulated in Het were further increased/decreased in Null. …”
Publicado 2020
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101349“…Delphi methodology was used to guide serial rounds of surveying and obtaining feedback from content matter experts from the International Hip Dysplasia Institute (IHDI), which continued in the same manner until consensus based on standard statistical analysis was reached. …”
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101350por Yoshida, Kenta, Moein, Anita, Bittner, Tobias, Ostrowitzki, Susanne, Lin, Helen, Honigberg, Lee, Jin, Jin Y., Quartino, Angelica“…RESULTS: The serum concentration of crenezumab increased in a dose-proportional manner between 15 and 120 mg/kg q4w. Total monomeric plasma Aβ(1–40) and Aβ(1–42) levels significantly increased after crenezumab administration. …”
Publicado 2020
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101351por Bellieny-Rabelo, Daniel, Nkomo, Ntombikayise Precious, Shyntum, Divine Yufetar, Moleleki, Lucy Novungayo“…By recruiting carR and expR1, the PhoP network also impacts certain host adaptation- and bacterial competition-related systems, seemingly in a quorum sensing-dependent manner, such as the type VI secretion system, carbapenem biosynthesis, and plant cell wall-degrading enzymes (PCWDE) like cellulases and pectate lyases. …”
Publicado 2020
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101352por Leong, Karen S. W., McLay, Jessica, Derraik, José G. B., Gibb, Sheree, Shackleton, Nichola, Taylor, Rachael W., Glover, Marewa, Audas, Rick, Taylor, Barry, Milne, Barry J., Cutfield, Wayne S.“…Results from covariate-adjusted analyses showed that both prenatal and early childhood exposures to antibiotics were independently associated with obesity at age 4 years, in a dose-dependent manner. Every additional course of antibiotics dispensed to the mothers yielded an adjusted odds ratio (aOR) of obesity in their children (siblings) of 1.02 (95% CI, 0.99-1.06), which was similar to the odds across pregnancy for the whole population (aOR, 1.06; 95% CI, 1.04-1.07). …”
Publicado 2020
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101353por Pettersen, Kristine, Andersen, Sonja, van der Veen, Anna, Nonstad, Unni, Hatakeyama, Shinji, Lambert, Christian, Lach‐Trifilieff, Estelle, Moestue, Siver, Kim, Jana, Grønberg, Bjørn Henning, Schilb, Alain, Jacobi, Carsten, Bjørkøy, Geir“…RESULTS: We show that activin A acts in an autocrine manner to promote the synthesis and secretion of IL‐6 from cancer cells. …”
Publicado 2019
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101354por Teng, Jin-Feng, Mei, Qi-Bing, Zhou, Xiao-Gang, Tang, Yong, Xiong, Rui, Qiu, Wen-Qiao, Pan, Rong, Law, Betty Yuen-Kwan, Wong, Vincent Kam-Wai, Yu, Chong-Lin, Long, Han-An, Xiao, Xiu-Li, Zhang, Feng, Wu, Jian-Ming, Qin, Da-Lian, Wu, An-Guo“…Moreover, by detecting the expression of NLRP3, ASC, caspase-1, IL-1β, IL-18 and GSDMD in A549 and h1299 cells using Western blotting, immunofluorescence imaging and flow cytometric analysis, measuring the caspase-1 activity using colorimetric assay, and quantifying the cytokines level of IL-1β and IL-18 using ELISA, the NLRP3 inflammasome was found to be activated in a dose manner, while VX-765 and necrosulfonamide (NSA), an inhibitor of GSDMD, could inhibit PPVI-induced activation of the NLRP3 inflammasome. …”
Publicado 2020
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101355por Zhu, Yu-ping, Zheng, Ze, Hu, Shaofan, Ru, Xufang, Fan, Zhuo, Qiu, Lu, Zhang, Yiguo“…Nrf1α (i.e., a full-length form) acts in a cell-autonomous manner to determine the transcription of most of UPR-target genes, albeit Nrf2 is also partially involved in this process. …”
Publicado 2019
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101356por Joag, Kaustubh, Kalha, Jasmine, Pandit, Deepa, Chatterjee, Susmita, Krishnamoorthy, Sadhvi, Shields-Zeeman, Laura, Pathare, Soumitra“…The intervention is rolled out in a staggered manner in these groups of villages at an interval of 5 months. …”
Publicado 2020
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101357por Bright, Tess, Shan, Xin, Xu, Jinling, Liang, Jianguo, Xiao, Baixiang, Ensink, Robbert, Mactaggart, Islay, Polack, Sarah, Yip, Jennifer L. Y.“…BACKGROUND: The Rapid Assessment of Hearing Loss (RAHL) survey protocol aims to measure the prevalence and causes of hearing loss in a low cost and rapid manner, to inform planning of ear and hearing services. …”
Publicado 2020
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101358por Xu, Huitao, Khan, Adnan, Zhao, Shanjiang, Wang, Huan, Zou, Huiying, Pang, Yunwei, Zhu, Huabin“…The results indicated a significant (p < 0.05) increase in the cell viability in a dose-dependent manner of inhibin A. Likewise, MMP was significantly (p < 0.05) enhanced when GCs were treated with high doses (50, 100 ng/mL) of inhibin A. …”
Publicado 2020
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101359“…What is more, the protein levels of phosphorylated AMPK α (p-AMPKα) and nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylase sirtuin-1 (SIRT1) were decreased by AA treatments in a time depending manner. Mitochondrial bioenergetics and the production of tricarboxylic acid cycle intermediates were decreased upon inhibition of mTORC1 or AMPK. …”
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101360por Houdebine, Louis Marie“…This is clearly due to the fact that the expression vectors are not constructed in an appropriate manner. This undoubtedly comes from the fact that all the signals contained in genes have not yet been identified. …”
Publicado 2000
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