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101721
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101722“…Classic FAP is inherited in an autosomal dominant manner and results from a germline mutation in the adenomatous polyposis (APC) gene. …”
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101723por Zhang, Jin-Zhong, Cavet, Megan E., VanDerMeid, Karl R., Salvador-Silva, Mercedes, López, Francisco J., Ward, Keith W.“…BOL-303242-X significantly reduced LPS- or IL-1ß-induced inflammatory cytokine release in a dose-dependent manner, including granulocyte colony-stimulating factor (G-CSF), IL-1ß, IL-6, IL-8, IL-12p40, monocyte chemotactic protein-1 (MCP-1), and tumor necrosis factor-α (TNF-α). …”
Publicado 2009
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101724“…RESULTS: Nine ORFs were noted to constitute rice class I Clp ATPases in the following manner: 3 ClpB proteins (ClpB-cyt, Os05g44340; ClpB-m, Os02g08490; ClpB-c, Os03g31300), 4 ClpC proteins (ClpC1, Os04g32560; ClpC2, Os12g12580; ClpC3, Os11g16590; ClpC4, Os11g16770) and 2 ClpD proteins (ClpD1, Os02g32520; ClpD2, Os04g33210). …”
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101725por Engström, Karin, Saldeen, Ann-Sofie, Yang, Baichun, Mehta, Jawahar L., Saldeen, Tom“…CONCLUSIONS: Both the EPA- and DHA-rich diets affected the blood lipids in a similarly positive manner, and they both had a large impact on plasma phospholipid fatty acids. …”
Publicado 2009
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101726“…CONCLUSIONS: Different Hk mutations affect the sleep phenotype, and do so in an age-dependent manner. In 4 of the 6 lines tested sleep associates significantly with lifespan variation even after any effect of activity is removed, but activity does not associate significantly with lifespan after the effects of sleep are removed. …”
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101727por Jiang, Lili, Huang, Qin, Zhang, Siyang, Zhang, Qingfu, Chang, Jihong, Qiu, Xueshan, Wang, Enhua“…In vitro gain-of-function experiments indicated that hsa-miR-125a-3p and hsa-miR-125a-5p function in an opposing manner, suppressing or enhancing cell migration and invasion in A549 and SPC-A-1 cell lines, respectively. …”
Publicado 2010
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101728por Stinson, Jennifer, McGrath, Patrick, Hodnett, Ellen, Feldman, Brian, Duffy, Ciaran, Huber, Adam, Tucker, Lori, Hetherington, Ross, Tse, Shirley, Spiegel, Lynn, Campillo, Sarah, Gill, Navreet, White, Meghan“…Usability testing is a crucial step in the development of self-management health portals to ensure that the various end users (youth and parents) have the ability to access, understand, and use health-related information and services that are delivered via the Internet and that they are delivered in an efficient, effective, satisfying, and culturally competent manner.…”
Publicado 2010
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101729“…Haemoglobin is capable of externally supplying the granulating wound bed with oxygen at low partial pressure in a physiological manner, like a micro lung, so that oxidative stress can be avoided. …”
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101730por Baines, Danica, Erb, Stephanie, Lowe, Ross, Turkington, Kelly, Sabau, Emil, Kuldau, Gretchen, Juba, Jean, Masson, Luke, Mazza, Alberto, Roberts, Ray“…Celmanax™ also directly decreased E. coli O157:H7 colonization of mucosal explants and a colonic cell line in a dose-dependent manner. There was no effect of Dairyman's Choice™ paste on E. coli O157:H7 colonization in vitro. …”
Publicado 2011
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101731por Hu, Chao-Chien, Liao, Jiahn-Haur, Hsu, Kuang-Yang, Lin, I-Lin, Tsai, Ming-Hsuan, Wu, Wen-Hsin, Wei, Tzu-Tang, Huang, Yi-Shiang, Chiu, Shih-Jiuan, Chen, Hsiang-Yin, Wu, Shih-Hsiung, Wu, Tzu-Hua“…The absolute γ-crystallin turbidity induced by 4 h of UVC exposure was ameliorated in the presence of catalin equivalent to 1~100 μM PRX in a concentration-dependent manner. Samples with catalin-formulated vehicle only (CataV) and those containing PRX equivalent to 100 μM had a similar protective effect after 4 h of UVC exposure compared to the controls (p<0.05). …”
Publicado 2011
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101732“…We show that the Sulfolobus solfataricus P2 DNA polymerase IV (Dpo4) bypasses AFB(1)–N7-dG in an error-free manner but conducts error-prone replication past the AFB(1)–FAPY adduct, including misinsertion of dATP, consistent with the G→T mutations observed in E. coli. …”
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101733
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101734
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101735por Hosing, Chitra, Munsell, Mark F, Reuben, James M, Popat, Uday, Lee, Bang-Ning, Gao, Hui, Körbling, Martin, Shpall, Elizabeth J, Kebriaei, Partow, Alousi, Amin, De Lima, Marcos, McMannis, John, Qazilbash, Muzaffar, Anderlini, Paolo, Giralt, Sergio, Champlin, Richard E, Khouri, Issa“…All patients were randomized in an adaptive manner to receive either G-CSF or G-CSF plus GM-CSF (G+GM) starting 24 hours after completion of chemotherapy and continuing until completion of apheresis. …”
Publicado 2010
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101736por Banerjee, Surajit, Christov, Plamen P., Kozekova, Albena, Rizzo, Carmelo J., Egli, Martin, Stone, Michael P.“…Replication bypass studies in vitro reveal that this polymerase inserted dNTPs opposite the (6S,8R,11S)-HNE-1,N(2)-dGuo adduct in a sequence-specific manner. If the template 5′-neighbor base was dCyt, the polymerase inserted primarily dGTP, whereas if the template 5′-neighbor base was dThy, the polymerase inserted primarily dATP. …”
Publicado 2012
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101737“…Furthermore, we have shown that local events such as microbleeding together with an accumulation of activated CD4+ T cells in a manner independent of tissue antigen-recognitions induces arthritis in the joints of F759 mice (Murakami et al., 2011). …”
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101738por Damm, U., Cannon, P.F., Woudenberg, J.H.C., Johnston, P.R., Weir, B.S., Tan, Y.P., Shivas, R.G., Crous, P.W.Enlace del recurso
Publicado 2012
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101739
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101740“…Receptor stimulation studies using HEK293 cells stably expressing the chicken PTH1R and PTH3R and monitoring cAMP production revealed they are activated by chicken 1–34 N-terminal PTH-family peptides in a dose dependent manner. PTH-L and PTHrP were the most effective peptides in activating PTH1R (EC(50) = 7.7 nM and EC(50) = 22.7 nM, respectively). …”
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