Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In all cases common guidelines of treatment of different iSPNs were followed in a routine manner. Results: Overall navigational yield (ny) was 91% and diagnostic yield (dy) 70%, dy for all accomplished malignant cases (n=28) was 82%. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Throughout each trial, athletes were randomly assigned, in a double-blind manner, either: (1) 1.1 g · min(-1) maltodextrin + 0.6 g · min(-1) fructose (MD + F), (2) 1.7 g · min(-1) of maltodextrin (MD) or (3) flavoured water (P). …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In summary, our findings in HCR/LCR rats provide protein-level confirmation for earlier transcriptome profiling work and show LC-MS is a viable means of profiling the abundance of almost all major metabolic enzymes of skeletal muscle in a highly parallel manner. Moreover, our approach is relatively more time efficient than techniques relying on orthogonal separations, and we demonstrate LC-MS profiling of the HCR/LCR selection model was able to highlight biomarkers that also exhibit differences in trained and untrained human muscle.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Both WIN55,212-2 (0.5 mg/kg/day s.c.) and AM1710 (3.2 mg/kg/day s.c.) increased CB(1) and CB(2) mRNA expression in lumbar spinal cord of paclitaxel-treated rats in a manner blocked by AM630. CONCLUSIONS AND IMPLICATIONS: Cannabinoids block development of paclitaxel-induced neuropathy and protect against neuropathic allodynia following cessation of drug delivery. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: We showed that BBR significantly inhibited growth and induced cell cycle arrest of non small cell lung cancer (NSCLC) cells in the G0/G1 phase in a dose-dependent manner. Furthermore, we found that BBR increased phosphorylation of p38 MAPK and ERK1/2 in a time-dependent and induced protein expression of tumor suppressor p53 and transcription factor FOXO3a in a dose-dependent fashion. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…NF- κB amyloid and STAT3, critical transcriptional factors regulating not only inflammation but also amyloidogenesis, were also inhibited in a concentration dependent manner by ent-Sauchinone by blocking the phosphorylation of I κB and STAT3 in cultured astrocytes and microglial BV-2 cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Purple carrot cultivars accumulate rich cyanidin-based anthocyanins in a light-independent manner in their taproots whereas other carrot color types do not. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As(2)O(3) treatment inhibits NF-κB p50 nuclear translocation, and induces B220 expression and cell death in a dose and time dependent manner. The levels of B220 induction on leukemic T cells strictly correlate with both the extent and form of cell death, B220 might therefore play a checkpoint role in death pathways. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…IRAK-M inhibited TLR2/4-mediated cytokine production in macrophages in a manner that is largely dependent on W74. R97 was not involved in inhibition of TNF production but was engaged in IL-6 down-regulation by IRAK-M. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In mouse xenograft model of HepG2 cells, SC-III3 showed a marked inhibition of tumor growth in a dose-dependent manner. Cell cycle analysis revealed that SC-III3 induced cells to accumulate in S phase, which was accompanied by a marked decrease of the expressions of cyclin A, cyclin B, cyclin E and Cdk2 proteins, the crucial regulators of S phase cell cycle. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Ethanol (EtOH), similar to pharmacologic mTOR inhibitors, has been shown to suppress the mTOR signaling pathway, though in a non-catalytic manner. Despite population studies showing that the consumption of EtOH has a protective effect against hematological malignancies, the mechanisms behind EtOH’s modulation of mTOR activity in cells and its downstream consequences are largely unknown. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Plant biomass that can with minimal pretreatment be degraded into sugars is required to produce renewable biofuels in a cost-effective manner. RESULTS: GAUT12/IRX8 is a putative glycosyltransferase proposed to be involved in secondary cell wall glucuronoxylan and/or pectin biosynthesis based on concomitant reductions of both xylan and the pectin homogalacturonan (HG) in Arabidopsis irx8 mutants. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Of these, 5 information presentation features improved comprehensibility in a manner reported previously in literature. CONCLUSIONS: To our knowledge, this is the first study to systematically analyze the most commonly used public reporting card designs used in Germany. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Those who are unable to access care in a timely manner may use the Internet to search for information needed to answer their health questions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…RESULTS: We showed that baicalein significantly inhibited growth and induced apoptosis of non-small cell lung cancer (NSCLC) cells in a time- and dose-dependent manner. Baicalein induced RUNX3 and FOXO3a protein expression, and increased phosphorylation of AMPKα and ERK1/2. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…White matter (WM) reactive astrocytes are important players in amplifying autoimmune demyelination and may exhibit different changes in transcriptome profiles and cell function in a disease-context dependent manner. However, their transcriptomic profile has not yet been defined because they are difficult to purify, compared to gray matter astrocytes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Our results show that patient sex and age significantly impact on weight loss in a procedure-dependent manner and should be considered when choosing between RYGBP and SG. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Besides its capacity to affect transcription in gene-dependent manner, 3-BrPA can also induce GLUT4-specific splicing silencing in both sensitive and resistant cells, thus dictating alternative routes of drug trafficking. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Aging influences immune response and susceptibility to EAE in a strain specific manner. The study was designed to examine influence of aging on EAE induction in Albino Oxford (AO) rats. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso