Mostrando 101,861 - 101,880 Resultados de 103,171 Para Buscar '"Mannerism"', tiempo de consulta: 0.52s Limitar resultados
  1. 101861
  2. 101862
  3. 101863
  4. 101864
    “…CONCLUSION: This present study demonstrates that WYHZTL formula has anti-fibrosis effect in Bleomycin-induced SSc mouse model in a dosage-dependent manner, and the molecular mechanism may be related to the inhibition of Wnt/β-catenin signaling pathway. …”
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  5. 101865
    “…Schizotypy is considered a suitable model for investigating schizophrenia as it mirrors the symptoms, albeit in a more subtle manner. As saccadic deficits are a cognitive hallmark of schizophrenia, it is believed that saccadic deficit may be associated with higher schizotypy. …”
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  6. 101866
    por Neves, Gilda, Grace, Anthony
    Publicado 2018
    “…DISCUSSION: In summary, our results show that alpha7 nAChR positive modulators can affect midbrain dopaminergic neuronal activity in vivo in a state-dependent manner. Interestingly, alpha7 nAChR agonists counterbalanced the hyperdopaminergic state of MAM rats and this effect is partially mediated by their action in the vHipp. …”
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  7. 101867
    por Hietala, Jarmo
    Publicado 2018
    “…The reduced CB1R in patients was also state-dependent as [18F]-FMPEP DVt correlated negatively with psychotic symptoms (BPRS) in a highly significant manner. DISCUSSION: Epidemiological studies have convincingly shown that cannabis use is associated with an increased risk of both psychotic symptoms and schizophrenia-like psychoses. …”
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  8. 101868
    “…METHODS: We used ultra-high field (7 Tesla) MRI in 28 patients with FEP (satisfying criterion A of DSM-5 schizophrenia) and 18 controls, to estimate grey matter volume in a voxelwise manner. FEP and controls were matched for age, sex and parental socioeconomic status. …”
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  9. 101869
    “…The doctor, nurses, a psychologist and an occupational therapist participated the group with different combinations and in a nonhierarchical manner. Psychoeducation was used to increase the knowledge and coping with the disorder. …”
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  10. 101870
    “…Furthermore, Smad6-facilitated recruitment of the de-ubiquitinase A20 to E3-ligases occurred in a bid-dependent manner. CONCLUSIONS: This study demonstrates that Bid promotes E3 ubiquitin ligase-mediated signaling downstream of TLR3 and TLR4 and provides further evidence for the potential of Bid inhibition as a therapeutic for the attenuation of the robust pro-inflammatory response culminating in TLR activation. …”
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  11. 101871
    “…RESULTS: Apo-SAA stimulated, in a time-dependent manner, the expression of NLRP3, IL-1β, and TNF-α in cortical microglia, and produced a concentration-dependent increase in the intracellular content of IL-1β in these cells. …”
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  12. 101872
    “…NDRG1 mRNA was elevated in a dose-dependent manner of LXA4, whereas BOC-2 antagonized NDRG1 expression induced by LXA4. …”
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  13. 101873
  14. 101874
    “…Lastly, another finding of this work is that geographic factors affect the climate-HFRS association in an interrelated manner through local climate or by means of HFRS infections. …”
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  15. 101875
    “…CONCLUSIONS: The observed DNA methylation changes together with the phenotypic findings suggest that rs10732516 polymorphism associates with the effects of ART in a parent-of-origin manner. Therefore, this polymorphism should be considered when the effects of environmental factors on embryonic development are studied. …”
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  16. 101876
    “…AKBA treatment was found to inhibit the survival of all four tested cell lines in a dose dependent manner. The combined treatment resulted in a more significant inhibitory effect compared to the effect of treatment with radiation alone. …”
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  17. 101877
    “…A better understanding of prognostic factors could potentially reduce the risk of re-nonunion happening and allow patients to maximize their recovery in the most expeditious manner. Our study aims to identify risk factors in the development of re-nonunion after primary revision inclusive of exchanging reamed nailing (ERN) and augmentative compression plating (ACP) with IMN in situ for femoral shaft nonunion subsequent to failed IMN. …”
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  18. 101878
    “…This study describes an attempt by Canadian stakeholders to develop an e-mental health assessment framework that responds to the unique needs of people living in Canada in an evidence-based manner. OBJECTIVE: The objective of our study was to achieve consensus from a broad group of Canadian stakeholders on guiding principles and criteria for a framework to assess e-mental health apps in Canada. …”
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  19. 101879
    “…It downregulated the phosphorylation of NF-κB (p65), IκBα, and IKKα/β and restored the degradation of IκBα, and attenuated the expression of Akt, JNK, ERK, and p38 MAPKs phosphorylation in a dose-dependent manner. P. amarus extract also downregulated the expression of upstream signaling molecules, TLR4 and MyD88, which play major role in activation of NF-κB, MAPK and PI3K-Akt signaling pathways. …”
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  20. 101880
    “…The results indicated that DCA inhibited human PASMC proliferation in a dose-dependent manner. DCA at 10 mM promoted apoptosis and the upregulation of activated caspase-3 in PASMCs pre-treated with 20 ng/ml PDGF-homeodimer BB (BB). …”
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