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102141por Khalid, Freeha, Takagi, Kiyoshi, Guestini, Fouzia, Miki, Yasuhiro, Miyashita, Minoru, Hirakawa, Hisashi, Ohi, Yasuyo, Rai, Yoshiaki, Sagara, Yasuaki, Suzuki, Takashi, Sasano, Hironobu“…However, CXCL1 was highly up-regulated in a dose and time-dependent manner after exposure to IL-17A, indicating that IL-17A might be involved in the recruitment of neutrophils through up-regulation of CXCL1. …”
Publicado 2022
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102142“…Metformin increases plasma lactate levels in a plasma concentration-dependent manner by inhibiting mitochondrial respiration predominantly in the liver. …”
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102143por Deng, Tingjuan, Hu, Boli, Wang, Xingbo, Ding, Shuxiang, Lin, Lulu, Yan, Yan, Peng, Xiran, Zheng, Xiaojuan, Liao, Min, Jin, Yulan, Dong, Weiren, Gu, Jinyan, Zhou, Jiyong“…Additionally, VP3 could inhibit TRAF6-mediated NFKB/NF-κB (nuclear factor kappa B) activation and IFNB/IFN-β (interferon beta) production to evade host innate immunity by inducing TRAF6 autophagic degradation in an SQSTM1/p62 (sequestosome 1)-dependent manner. Our findings demonstrated a macroautophagic/autophagic mechanism by which Avibirnavirus protein VP3 blocked NFKB-mediated IFNB production by targeting TRAF6 during virus infection, and provided a potential drug target for virus infection control. …”
Publicado 2022
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102144por Sammarco, Josika, Zhu, Mingjie, Ansah-Twum, Jeremy, Baldini, Todd H., Cephers, Candace, Hunt, Kenneth J., Myerson, Mark S., Li, Shuyuan“…The Achilles insertion and musculotendinous junction were fully exposed to ensure that tenotomies were performed in a standardized manner. Lengthening was measured with optical markers at the most distal cut and 15 cm proximally. …”
Publicado 2022
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102145por Weisinger, Batsheva, Pandey, Dharam P., Saver, Jeffrey L., Hochberg, Arielle, Bitton, Adina, Doniger, Glen M., Lifshitz, Assaf, Vardi, Ofir, Shohami, Esther, Segal, Yaron, Reznik Balter, Shira, Djemal Kay, Yael, Alter, Ariela, Prasad, Atul, Bornstein, Natan M.“…Exposure to extremely low frequency and low intensity electromagnetic fields (ELF-EMF) in a frequency-specific manner (Electromagnetic Network Targeting Field therapy; ENTF therapy) is a non-invasive method available to a wide range of patients that may enhance neuroplasticity, potentially facilitating motor recovery. …”
Publicado 2022
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102146por Xie, Wenting, Su, Fugui, Wang, Guizhong, Peng, Zichong, Xu, Yaomin, Zhang, Yi, Xu, Ningning, Hou, Kaijian, Hu, Zhuping, Chen, Yan, Chen, Rongping“…In recent years, researchers have discovered that berberine can inhibit the voltage-gated k(+) channels of pancreatic β cell membrane and promote insulin secretion without causing hypoglycemia, because the glucose-lowering effects of berberine are only under hyperglycemic conditions or in a high-glucose-dependent manner. In order to shed light on the glucose-lowing effects of berberine in type 2 diabetes with different baseline fasting plasma glucose (FPG) and glycosylated hemoglobin (HbA1c), we conducted a meta-analysis of randomized controlled trials. …”
Publicado 2022
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102147por Shao, Xiaoyan, Gong, Wang, Wang, Qianjin, Wang, Pu, Shi, Tianshu, Mahmut, Abdurahman, Qin, Jianghui, Yao, Yao, Yan, Wenjin, Chen, Dongyang, Chen, Xiang, Jiang, Qing, Guo, Baosheng“…A series of myokines/small extracellular vesicles (sEVs) released from muscle fibres regulate metabolism in muscle and extramuscular tissues in an autocrine/paracrine/endocrine manner during muscle atrophy. It is still unclear whether myokines/sEVs derived from muscle fibres can affect satellite cell function during ageing. …”
Publicado 2022
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102148por Cheng, Fang, Hu, Changzhou, Zhang, Wenwu, Xie, Huabing, Shen, Liangliang, Wang, Beini, Hu, Zhenyu, Wang, Yucheng, Yu, Haihang“…CONCLUSION: In particular, we investigated the mediating effects of gender-specific NSSI influences and found that NSSI behaviors were strongly associated with environmental variables and individual factors, especially family parenting style and adolescent coping style, which influenced NSSI in a gender-specific manner. The results showed that males were the target of both positive and negative parenting styles, whereas females were more likely to choose negative coping styles directed towards emotions in response to external stimuli, and instead showed a more significant predisposition towards NSSI behaviors. …”
Publicado 2022
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102149“…This study shows the genetic events that happened to mcr-10.1 in a stepwise manner, with the first step being XerC integration and the second being ISEc36 mobilization. …”
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102150por Okyere, Joshua, Azure, Simon Agongo, Budu, Eugene, Mensah, Felix, Ahinkorah, Bright Opoku, Ameyaw, Edward Kwabena, Seidu, Abdul-Aziz“…This calls for a comprehensive and all-inclusive approach that enhances Vitamin A supplementation uptake in an equitable manner in both areas of residence. Empowerment of women through formal education could be an important step toward improving Vitamin A supplementation among children in Ghana.…”
Publicado 2022
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102151“…Therefore, a lower ratio of n-6: n-3 PUFAs, with higher intake of n-3 PUFAs in paternal pre-conception, may help maintain the offspring’s optimal leptin pattern in a sex-specific manner through multiple generations, and thereby, be beneficial for the offspring’s long-term health.…”
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102152“…CONCLUSIONS: Both types of combination treatments were successful in altering the patellofemoral joint in a satisfactory manner, and the knee function improved in both groups. …”
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102153“…The present study aimed to predict the outcome of patients with PCS following rt-PA thrombolytic therapy in a more efficient manner. Data were collected from patients who had suffered from posterior circulation ischemic stroke, who had been treated with rt-PA over a period of 4 years (2016-2020), and had been treated at a stroke center. …”
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102154“…Interestingly, the expression of vinculin mRNA steadily decreased in a time‐dependent manner. The vinculin expression reached its peak at 6 h in each group, and the vinculin levels in bone fiber, bone powder, and bone granule group were 2.119 ± 0.052, 3.842 ± 0.108, and 3.585 ± 0.068 times higher than those in the control group, respectively (F = 733.643, all P < 0.001). …”
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102155por Ma, Ting Martin, Sun, Yilun, Malone, Shawn, Roach, Mack, Dearnaley, David, Pisansky, Thomas M., Feng, Felix Y., Sandler, Howard M., Efstathiou, Jason A., Syndikus, Isabel, Hall, Emma C., Tree, Alison C., Sydes, Matthew R., Cruickshank, Claire, Roy, Soumyajit, Bolla, Michel, Maingon, Philippe, De Reijke, Theo, Nabid, Abdenour, Carrier, Nathalie, Souhami, Luis, Zapatero, Almudena, Guerrero, Araceli, Alvarez, Ana, Gonzalez San-Segundo, Carmen, Maldonado, Xavier, Romero, Tahmineh, Steinberg, Michael L., Valle, Luca F., Rettig, Matthew B., Nickols, Nicholas G., Shoag, Jonathan E., Reiter, Robert E., Zaorsky, Nicholas G., Jia, Angela Y., Garcia, Jorge A., Spratt, Daniel E., Kishan, Amar U.“…The sequencing of androgen-deprivation therapy (ADT) with radiotherapy (RT) may affect outcomes for prostate cancer in an RT-field size-dependent manner. Herein, we investigate the impact of ADT sequencing for men receiving ADT with prostate-only RT (PORT) or whole-pelvis RT (WPRT). …”
Publicado 2023
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102156por Wahba, Mohamed A., Mofed, Dina, Ghareeb, Doaa A., Omran, Jihad I., Salem, Tamer Z.“…BALB/C mice were immunized with the pseudotyped baculoviruses in a dose-optimized manner. Dot blot and Western blot were used to screen and validate the polyclonal antibodies’ specificity to the SARS-CoV-2 RBD. …”
Publicado 2023
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102157“…OBJECTIVE: To determine whether an individual’s level of eHealth literacy affects actual health-related behaviors, the correlation between eHealth literacy and health-related behaviors was identified in an integrated manner through a systematic literature review and meta-analysis. …”
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102158por Li, Sanzhong, Mu, Yunfeng, Rao, Yang, Sun, Chuanzhu, Li, Xiang, Liu, Huan, Yu, Xun, Yan, Xiao, Ding, Yunxia, Wang, Yangtao, Fei, Zhou“…DES hotspots (HS(DES)) were also determined in a manner analogous to HS(nTMS). The spatial distribution of HS(nTMS) and HS(DES) in the nTMS group was recorded, registered in a single brain template, and compared. …”
Publicado 2023
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102159por Lin, Weiyin, Zhong, Huolin, Wen, Chunyan, He, Yaozu, Zheng, Xiaowen, Li, Hong, Chen, Xiejie, He, Haolan, Chen, Jinfeng, Chen, Lijuan, Liu, Cong, Tang, Xiaoping, Cai, Weiping, Li, Linghua“…Peak CD4 was negatively associated with the risk of hepatic events in a dose–response manner (P-value for trend = 0.004). CONCLUSION: Persistently low CD4 cell counts after ART are independently associated with a high risk of hepatic events in HCV/HIV-coinfected patients, highlighting the important role of immune reconstitution in improving liver outcomes.…”
Publicado 2022
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102160“…After hypoxia and DNA damage, IRE1A and XBP-1 were repressed by p53 in a miR-34a-dependent manner, whereas p53-deficient cells showed induction of IRE1A and XBP-1(S). …”
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