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  1. 102661
    “…Atom environments were created in a circular manner focused on a central atom with radii from 0 (atom types) up to 3 (representative of ECFP_6 fragments). …”
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    PubChem atom environments
  2. 102662
    “…CHR inhibited in vitro activity of CYP1A2 and CYP2C19 (P < 0.01, IC(50) = 4.61 and 6.23 μM) in a concentration–response manner. The inhibition did not emerge on CYP2E1 and CYP3A until the CHR concentration exceeded 4.0 μM (P < 0.01, IC(50) = 28.17 and 3.38 µM). …”
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    Impact of chrysosplenetin on the pharmacokinetics and anti-malarial efficacy of artemisinin against Plasmodium berghei as well as in vitro CYP450 enzymatic activities in rat liver microsome
  3. 102663
    “…Then, we performed a statistical analysis in a consistent manner using linear mixed effect models. The models, one for repeated measures of volume made at multiple time-points and a second for repeated “direct” measures of change in brain volume, appropriately allowed for the correlation between measures made on the same subject and were shown to fit the data well. …”
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    Assessing atrophy measurement techniques in dementia: Results from the MIRIAD atrophy challenge
  4. 102664
    “…METHODS: We used two experimental mouse models of skin-specific inflammation generated in either an acute (topical Aldara application onto wild-type C57Bl/6 mice for 5 days) or chronic (a genetically engineered K5-IL-17C mouse model of psoriasiform skin inflammation) manner. Arterial thrombosis was induced using carotid artery photochemical injury (Rose Bengal-green light laser) and carotid artery diameters were measured post-clot formation. …”
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    Chronic, not acute, skin-specific inflammation promotes thrombosis in psoriasis murine models
  5. 102665
    por Rossman, Amy Y., Crous, Pedro W., Hyde, Kevin D., Hawksworth, David L., Aptroot, André, Bezerra, Jose L., Bhat, Jayarama D., Boehm, Eric, Braun, Uwe, Boonmee, Saranyaphat, Camporesi, Erio, Chomnunti, Putarak, Dai, Dong-Qin, D’souza, Melvina J., Dissanayake, Asha, Gareth Jones, E.B., Groenewald, Johannes Z., Hernández-Restrepo, Margarita, Hongsanan, Sinang, Jaklitsch, Walter M., Jayawardena, Ruvishika, Jing, Li Wen, Kirk, Paul M., Lawrey, James D., Mapook, Ausana, McKenzie, Eric H.C., Monkai, Jutamart, Phillips, Alan J.L., Phookamsak, Rungtiwa, Raja, Huzefa A., Seifert, Keith A., Senanayake, Indunil, Slippers, Bernard, Suetrong, Satinee, Taylor, Joanne E., Thambugala, Kasun M., Tian, Qing, Tibpromma, Saowaluck, Wanasinghe, Dhanushka N., Wijayawardene, Nalin N., Wikee, Saowanee, Woudenberg, Joyce H.C., Wu, Hai-Xia, Yan, Jiye, Yang, Tao, Zhang, Ying
    Publicado 2015
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    Recommended names for pleomorphic genera in Dothideomycetes
  6. 102666
    “…The increasing recognition that the gut microbiota plays a central role in behavior and cognition suggests that the manipulation of microbial taxa through diet may provide a means by which behavior may be altered in a reproducible and consistent manner in order to achieve a beneficial outcome for the host. …”
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    Resistant Starch Alters the Microbiota-Gut Brain Axis: Implications for Dietary Modulation of Behavior
  7. 102667
    “…A potential limitation of the study is its open-label design, although the primary outcome measures were assessed in a blinded manner. CONCLUSIONS: A simplified three-dose i.m. regimen for severe malaria in African children is non-inferior to the more complex WHO-recommended regimen. …”
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    Intramuscular Artesunate for Severe Malaria in African Children: A Multicenter Randomized Controlled Trial
  8. 102668
    por Stielow, J.B., Lévesque, C.A., Seifert, K.A., Meyer, W., Iriny, L., Smits, D., Renfurm, R., Verkley, G.J.M., Groenewald, M., Chaduli, D., Lomascolo, A., Welti, S., Lesage-Meessen, L., Favel, A., Al-Hatmi, A.M.S., Damm, U., Yilmaz, N., Houbraken, J., Lombard, L., Quaedvlieg, W., Binder, M., Vaas, L.A.I., Vu, D., Yurkov, A., Begerow, D., Roehl, O., Guerreiro, M., Fonseca, A., Samerpitak, K., van Diepeningen, A.D., Dolatabadi, S., Moreno, L.F., Casaregola, S., Mallet, S., Jacques, N., Roscini, L., Egidi, E., Bizet, C., Garcia-Hermoso, D., Martín, M.P., Deng, S., Groenewald, J.Z., Boekhout, T., de Beer, Z.W., Barnes, I., Duong, T.A., Wingfield, M.J., de Hoog, G.S, Crous, P.W., Lewis, C.T., Hambleton, S., Moussa, T.A.A., Al-Zahrani, H.S., Almaghrabi, O.A., Louis-Seize, G., Assabgui, R., McCormick, W., Omer, G., Dukik, K., Cardinali, G., Eberhardt, U., de Vries, M., Robert, V.
    Publicado 2015
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    One fungus, which genes? Development and assessment of universal primers for potential secondary fungal DNA barcodes
  9. 102669
    por Crous, P.W., Wingfield, M.J., Le Roux, J.J., Richardson, D.M., Strasberg, D., Shivas, R.G., Alvarado, P., Edwards, J., Moreno, G., Sharma, R., Sonawane, M.S., Tan, Y.P., Altés, A., Barasubiye, T., Barnes, C.W., Blanchette, R.A., Boertmann, D., Bogo, A., Carlavilla, J.R., Cheewangkoon, R., Daniel, R., de Beer, Z.W., de Jesús Yáñez-Morales, M., Duong, T.A., Fernández-Vicente, J., Geering, A.D.W., Guest, D.I., Held, B.W., Heykoop, M., Hubka, V., Ismail, A.M., Kajale, S.C., Khemmuk, W., Kolařík, M., Kurli, R., Lebeuf, R., Lévesque, C.A., Lombard, L., Magista, D., Manjón, J.L., Marincowitz, S., Mohedano, J.M., Nováková, A., Oberlies, N.H., Otto, E.C., Paguigan, N.D., Pascoe, I.G., Pérez-Butrón, J.L., Perrone, G., Rahi, P., Raja, H.A., Rintoul, T., Sanhueza, R.M.V., Scarlett, K., Shouche, Y.S., Shuttleworth, L.A., Taylor, P.W.J., Thorn, R.G., Vawdrey, L.L., Solano-Vidal, R., Voitk, A., Wong, P.T.W., Wood, A.R., Zamora, J.C., Groenewald, J.Z.
    Publicado 2015
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    Fungal Planet description sheets: 371–399
  10. 102670
    “…Consultation with producers and consumers should be more formalized to ensure their concerns are incorporated into regular policy reviews in an appropriate and transparent manner. However, despite the limited available knowledge on best practice in food control and enforcement of provisional radio-contamination limits after the accident, current Japanese policy is sufficient to protect the Japanese public from major risk of radio-contamination from the commercial food market.…”
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    Current Measures on Radioactive Contamination in Japan: A Policy Situation Analysis
  11. 102671
    “…During the second visit the alternative supplement was ingested and the assessments were repeated in the exact same manner. Data were analyzed via a 2-factor [2x4] within-subjects repeated measures analysis of variance (ANOVA). …”
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    The effects of a fat loss supplement on resting metabolic rate and hemodynamic variables in resistance trained males: a randomized, double-blind, placebo-controlled, cross-over trial
  12. 102672
    “…CONCLUSION: While numerous studies have evaluated the operative versus non-operative treatment of type III injuries in both a prospective and retrospective manner, no study to date has reported on the conservative treatment of type V AC dislocations. …”
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    Successful Conservative Therapy in Rockwood Type V Acromioclavicular Dislocations
  13. 102673
    “…Improvement in health-related communication was appreciated by oncologists, oncology nurses, and patients with respect to communicating health related information in a sensitive manner (Z = −3.74, P = 0.001), (Z = −5.47, P = 0.001), (Z = −6.12, P = 0.001); conducting family meeting (Z = −3.12, P = 0.002), (Z = −4.60, P = 0.001), (Z = −5.90, P = 0.001); discussing goals of care (Z = −3.43, P = 0.001), (Z = −5.49, P = 0.001), (Z = −5.61, P = 0.001); maintaining hope (Z = −3.22, P = 0.001), (Z = −4.85, P = 0.001), (Z = −5.61, P = 0.001); and resolution of conflict (Z = −3.56, P = 0.001), (Z = −5.29, P = 0.001), (Z = −5.28, P = 0.001). …”
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    Integration of Early Specialist Palliative Care in Cancer Care: Survey of Oncologists, Oncology Nurses, and Patients
  14. 102674
    “…All travelers returning from Liberia, Sierra Leone, and Guinea during 10/21/14–5/15/15 were monitored by MDH staff in the manner recommended by CDC based on the traveler’s risk categorization as “low (but not zero)”, “some” and “high” risk. …”
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    Development and Implementation of the Ebola Traveler Monitoring Program and Clinical Outcomes of Monitored Travelers during October – May 2015, Minnesota
  15. 102675
    “…More detailed information about the cohorts such as race or sociodemographic factors were reported in an ad hoc manner. Common sources of bias included contamination, co-intervention, or lack of operational definition for some outcomes (e.g., wound healing) as illustrative examples. …”
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    Outcomes of dysvascular partial foot amputation and how these compare to transtibial amputation: a systematic review for the development of shared decision-making resources
  16. 102676
    por May, Tom W.
    Publicado 2017
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    Report of the Nomenclature Committee for Fungi – 20
  17. 102677
    “…Fluc activity increased in MSC-Tet-TK/Fluc cells in a dose dependent manner following DOX treatment (R2 = 0.95), whereas no signal was observed in untreated cells. eGFP could also be visualized after induction with DOX, and the HSV1-TK protein could be detected by western blotting. …”
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    Genetically engineered suicide gene in mesenchymal stem cells using a Tet-On system for anaplastic thyroid cancer
  18. 102678
    “…As most of the stillbirths are preventable with high-quality, evidence-based interventions delivered before and during pregnancy and during labour and childbirth, it is imperative that with INAP in place, India aspires to document stillbirths in a systematic and standardised manner to bridge the knowledge gap for appropriate actions to reduce stillbirths. …”
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    Identification of factors associated with stillbirth in the Indian state of Bihar using verbal autopsy: A population-based study
  19. 102679
    “…It is insufficiently known to what degree patients adhere to agreed self-assessment schedule over the long term and whether questionnaires are filled out in a timely manner. OBJECTIVE: The objective of this study was to investigate patients’ adherence to a self-assessment schedule with low-frequency long questionnaires versus that with a high-frequency short questionnaire. …”
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    Adherence to Web-Based Self-Assessments in Long-Term Direct-to-Patient Research: Two-Year Study of Multiple Sclerosis Patients
  20. 102680
    por Mikami, Koichi, Sturdy, Steve
    Publicado 2017
    “…With additional input from social scientists who offered different perspectives on the value of patient involvement, the workshop aimed to initiate a dialogue among the participants about how to address the challenge in a sustainable manner. Discussions at the workshop stressed that active involvement of patients is as valuable in the regulatory and commissioning processes as in the research and development of new medicines. …”
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    Patient organization involvement and the challenge of securing access to treatments for rare diseases: report of a policy engagement workshop
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