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  1. 102721
    “….; Belgium), the pre-processed 3D model was manipulated in a standardized manner to simulate 5-degree incremental variations in FV and NSA (-15 degrees to +15 degrees for FV; -15 degrees to +10 degrees for NSA). …”
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    Standard Radiographic Assessment of Femoral Cam Morphology is Influenced by Neck-Shaft Angle and Femoral Version
  2. 102722
    “…After adequate warm-up, pitchers were fitted with a MOTUS sensor baseball sleeve (Motus Global, Massapequa, NY) and instructed to throw 5 fastballs in a standardized manner off the mound at game-speed effort. The sensor placed at the medial elbow reported elbow torque, arm speed, arm slot, and shoulder rotation for each pitch, while a radar gun measured peak ball velocity. …”
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    The Relationship Between Shoulder Range of Motion and Arm Stress in College Pitchers: A MOTUS Baseball Study
  3. 102723
    “…A total of 21,691 papers were found and screened in a phased manner. Data were extracted from the eligible papers into a detailed Microsoft Excel tool, extensively cleaned and analysed with R software (R Project, Vienna, Austria) using the user interface of RStudio. …”
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    A Systematic Review of Methodological Variation in Healthcare Provider Perspective Tuberculosis Costing Papers Conducted in Low- and Middle-Income Settings, Using An Intervention-Standardised Unit Cost Typology
  4. 102724
    “…Both groups were treated in a similar manner. Patients took their usual medications, wore a wrist-worn activity tracker, and checked their eMoodChart daily. …”
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    Effectiveness of a Smartphone App With a Wearable Activity Tracker in Preventing the Recurrence of Mood Disorders: Prospective Case-Control Study
  5. 102725
    “…There is a consensus that elimination of malaria is feasible when rapid detection and prompt treatment is combined with mosquito-human contact interruption in an efficient and sustainable manner at community levels. This paper describes results of an integrated case management and vector control strategy for reducing malaria cases in 1233 villages over 3 years in district Mandla, Madhya Pradesh, India. …”
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    Demonstration of indigenous malaria elimination through Track-Test-Treat-Track (T4) strategy in a Malaria Elimination Demonstration Project in Mandla, Madhya Pradesh
  6. 102726
    “…Nursing leadership is needed to safeguard the quality of care and nursing staff should work together within an interprofessional care team to initiate advance care planning conversations in a timely manner, to review and document advance care plans, and to adapt goals of care as they may change due to the COVID-19 situation. …”
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    Practical nursing recommendations for palliative care for people with dementia living in long-term care facilities during the COVID-19 pandemic: A rapid scoping review
  7. 102727
    “…E6 and E7 are produced from two mRNAs that are generated in a mutually exclusive manner by alternative splicing. While E6 protein is made from the unspliced mRNA, E7 is made from the spliced version of the same pre-mRNA. …”
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    Heterogeneous Nuclear Ribonucleoprotein A1 (hnRNP A1) and hnRNP A2 Inhibit Splicing to Human Papillomavirus 16 Splice Site SA409 through a UAG-Containing Sequence in the E7 Coding Region
  8. 102728
    “…Visual predictive check plots showed greater variability in the 6- to 11-year-old group than the 4- to < 6-year-old group, and CL increased with increasing body weight in a greater than dose-proportional manner. Mean CL, normalized for body weight, was constant for all dose groups, ranging from 4.88 L/h/kg to 5.80 L/h/kg. …”
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    A Pharmacokinetic Study of Methylphenidate Hydrochloride Multilayer Extended-Release Capsules (Aptensio XR(®)) in Preschool-Aged Children with Attention-Deficit/Hyperactivity Disorder
  9. 102729
    “…The model for physical activity–related health competence describes possibilities to empower patients to perform physical exercises in the best possible health-promoting manner while taking into account their own physical condition. …”
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    Effectiveness of Human Versus Computer-Based Instructions for Exercise on Physical Activity–Related Health Competence in Patients with Hip Osteoarthritis: Randomized Noninferiority Crossover Trial
  10. 102730
    “…IMPORTANCE: Suicide has been a leading manner of death for US Air Force personnel in recent years. …”
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    Effect of the Wingman-Connect Upstream Suicide Prevention Program for Air Force Personnel in Training: A Cluster Randomized Clinical Trial
  11. 102731
    “…The extent to which information found on the internet reflects these medical facts in a trustworthy and unbiased manner is not known. OBJECTIVE: The purpose of this study was to collate and describe the trustworthiness and political slant or bias of web-based information about abortion safety and risks of depression and infertility following abortion. …”
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    The Abortion Web Ecosystem: Cross-Sectional Analysis of Trustworthiness and Bias
  12. 102732
    “…Normally, the activity of NRF2 is tightly controlled in the cell, and is continuously adjusted to ensure that cells are protected against endogenous chemicals and environmental agents that perturb the intracellular antioxidant/pro-oxidant balance (i.e., redox) that must be maintained for them to grow and survive in an appropriate manner. This tight control of NRF2 is achieved by a repressor protein called KEAP1 that perpetually targets NRF2 protein for degradation under normal conditions, but is unable to do so when challenged with oxidants or thiol-reactive chemicals. …”
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    NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis
  13. 102733
    “…Staff reported perceived advantages for patients: reduced stigma of pill bottles (38%), ability to live/travel in a “carefree” manner (31%) and removing the daily reminder of HIV (20%). …”
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    1037. Qualitative Findings from a Hybrid III Implementation-Effectiveness Study to Explore Perspectives of Health-care Staff on Early Implementation of Cabotegravir and Rilpivirine Long Acting (CAB+RPV LA) Injectable HIV treatment in the US (CUSTOMIZE)
  14. 102734
    “…Providers and administrators participated in a 3-hour virtual reality training program consisting of 360-degree videos produced in a professional, cinematic manner; this technique is called virtual reality cinema (cine-VR). …”
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    Using Virtual Reality to Improve Health Care Providers’ Cultural Self-Efficacy and Diabetes Attitudes: Pilot Questionnaire Study
  15. 102735
    “…Conclusions: PPI for clinical trials can be conducted in a time-efficient manner within the pressured environment of a pandemic. …”
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    Patient and public involvement prior to trial initiation: lessons learnt for rapid partnership in the COVID-19 era
  16. 102736
    “…Conclusions: Results suggest a role of Nourin-associated miR-137 and miR-106b-5p in the pathogenesis of HF and that CCrP treatment prevented ischemic injury in “non-HF rats” and significantly reduced Nourin gene expression levels in a dose–response manner. The Nourin gene-based mRNAs may, therefore, potentially be used as monitoring markers of drug therapy response in HF, and CCrP—as a novel preventive therapy of HF due to ischemia.…”
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    Nourin-Associated miRNAs: Novel Inflammatory Monitoring Markers for Cyclocreatine Phosphate Therapy in Heart Failure
  17. 102737
    “…This analysis was then used to recommend realistic approaches to build a smartphone-based point-of-care tool for hemoglobin measurement in a noninvasive manner. RESULTS: The fingertip area is one of the best data collection sites from the body, followed by the lower eye conjunctival area. …”
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    Noninvasive Hemoglobin Level Prediction in a Mobile Phone Environment: State of the Art Review and Recommendations
  18. 102738
    por King, Anthony J, Hudson, Jemma, Fernie, Gordon, Kernohan, Ashleigh, Azuara-Blanco, Augusto, Burr, Jennifer, Homer, Tara, Shabaninejad, Hosein, Sparrow, John M, Garway-Heath, David, Barton, Keith, Norrie, John, McDonald, Alison, Vale, Luke, MacLennan, Graeme, King, Anthony, Agrawal, Pavi, Stead, Richard, Broadway, David C, Strouthidis, Nick, Chew, Shenton, Sng, Chelvin, Toth, Marta, Gazzard, Gus, Elkarmouty, Ahmed, Nikita, Eleni, Triolo, Giacinto, Aguilar-Munoa, Soledad, Goyal, Saurabh, Lim, Sheng, Sung, Velota, Masood, Imran, Wride, Nicholas, Sandhu, Amanjeet, Hill, Elizabeth, Sparrow, John, Grey, Fiona, Bourne, Rupert, Nithyanandarajah, Gnanapragasam, Willshire, Catherine, Bloom, Philip, Ahmed, Faisal, Cordeiro, Franesca, Crawley, Laura, Normando, Eduardo, Ameen, Sally, Tryfinopoulou, Joanna, Porteous, Alistair, Jutley, Gurjeet, Bessinis, Dimitrios, Kirwan, James, Begum, Shahiba, Sepetis, Anastasios, Rule, Edward, Thornton, Richard, McNaught, Andrew, Anand, Nitin, Negi, Anil, Kousha, Obaid, Hovan, Marta, Sanders, Roshini, Agarwal, Pankaj Kumar, Tatham, Andrew, Au, Leon, Fenerty, Cecelia, Karaconji, Tanya, Drury, Brett, Penmol, Duya, Ansari, Ejaz, Dardzhikova, Albina, Moosavi, Reza, Imonikhe, Richard, Kontovourikis, Prodromos, Membrey, Luke, Almeida, Goncalo, Tildsley, James, Azuara-Blanco, Augusto, Knox, Angela, Rankin, Simon, Wilson, Sara, Prabhu, Avinash, Mukherji, Subhanjan, Datta, Amit, Fern, Alisdair, Liput, Joanna, Manners, Tim, Pilling, Josh, Stemp, Clare, Martin, Karen, Nixon, Tracey, Cobb, Caroline, Rotchford, Alan, Sidiki, Sikander, Bansal, Atul, Kousha, Obaid, Auger, Graham, Freeman, Mary
    Publicado 2021
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    Primary trabeculectomy for advanced glaucoma: pragmatic multicentre randomised controlled trial (TAGS)
  19. 102739
    “…BACKGROUND: There is a strong demand for an accurate and objective means of assessing acute pain among hospitalized patients to help clinicians provide pain medications at a proper dosage and in a timely manner. Heart rate variability (HRV) comprises changes in the time intervals between consecutive heartbeats, which can be measured through acquisition and interpretation of electrocardiography (ECG) captured from bedside monitors or wearable devices. …”
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    Pain Recognition With Electrocardiographic Features in Postoperative Patients: Method Validation Study
  20. 102740
    “…Upon acute ischemia, an initial autophagy modification occurred in an upregulation manner. Following, the number of lysosomes increased, as well as lysosomal volume, indicating dysfunctional lysosomal storage. …”
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    Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons
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