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102901por Liu, Xin, Wu, Tao, Zhu, Su-Yu, Shi, Mei, Su, Hang, Wang, Ying, He, Xia, Xu, Li-Ming, Yuan, Zhi-Yong, Zhang, Li-Ling, Wu, Gang, Qu, Bao-Lin, Qian, Li-Ting, Hou, Xiao-Rong, Zhang, Fu-Quan, Zhang, Yu-Jing, Zhu, Yuan, Cao, Jian-Zhong, Lan, Sheng-Min, Wu, Jun-Xin, Qi, Shu-Nan, Yang, Yong, Li, Ye-Xiong“…CONCLUSIONS AND RELEVANCE: The survival probability increased and the hazards of failure decreased in a risk-dependent manner among patients with early NKTCL after radiotherapy. …”
Publicado 2019
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102902por Borghi, Sergio M., Fattori, Victor, Pinho-Ribeiro, Felipe A., Domiciano, Talita P., Miranda-Sapla, Milena M., Zaninelli, Tiago H., Casagrande, Rubia, Pinge-Filho, Phileno, Pavanelli, Wander R., Alves-Filho, Jose C., Cunha, Fernando Q., Cunha, Thiago M., Verri, Waldiceu A.“…TNF-α and IL-1β blood levels were not changed over the time course of disease, and parasitism increased in a time-dependent manner in the ipsilateral draining lymph node. Treatments targeting CX(3)CL1, TNF-α, and IL-1β inhibited L. amazonensis-induced ongoing mechanical and thermal hyperalgesia, but not paw edema. …”
Publicado 2019
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102903por Jiang, Wei-Wei, Wang, Yi-Meng, Wang, Xiao-Yu, Zhang, Qian, Zhu, Si-Man, Zhang, Chun-Lei“…RESULTS: Cell proliferation inhibition was seen in HaCaT cells with treatment of matrine in a dose- and time-dependent manner (P < 0.01, respectively). Cell cycle G0/G1 phase arrest was observed in a dose-dependent way (P < 0.01). …”
Publicado 2019
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102904“…In the detection of immune effector cell activity in immunosuppressive mice, the phagocytic function of macrophages in high dose group and the natural killing activity of spleen NK cells in high dose drug group were significantly increased, which were not significantly different from those in positive control group (P < 0.05), but the expression of TNF-α, INF-γ and IL-4 cytokines in serum was increased in a dose dependent manner (p < 0.05). In conclusion, soybean oligosaccharide can significantly increase the diversity of intestinal microecology, increase the number of intestinal beneficial bacteria, has a correlation with the proliferation of Bifidobacterium and Lactobacillus in the intestinal tract, and inhibit the proliferation of harmful bacteria. …”
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102905por Jinzaki, Masahiro, Yamada, Yoshitake, Nagura, Takeo, Nakahara, Takehiro, Yokoyama, Yoichi, Narita, Keiichi, Ogihara, Naomichi, Yamada, Minoru“…In 3 patients, upright CT revealed lumbar foraminal stenosis, bladder prolapse, and inguinal hernia; moreover, it clarified the grade or clinical significance of the disease in a manner that was not apparent on conventional CT. CONCLUSIONS: Upright CT was comparable to supine CT in physical characteristics, and it significantly reduced the access time for examination. …”
Publicado 2020
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102906“…In addition, jurisdictions might choose to collect surveillance data themselves in a similar manner to what NTSIP states did. Chemical incident surveillance data can be used by public health and safety practitioners, worker representatives, emergency planners, preparedness coordinators, industries, and emergency responders to prepare for and prevent chemical incidents and injuries. …”
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102907por Peris-Yague, Alba, Kiemes, Amanda, Cash, Diana, Cotel, Marie-Caroline, Singh, Nisha, Vernon, Anthony, Modinos, Gemma“…DISCUSSION: This is the first study to investigate, in healthy rats, the effects of clinically-relevant doses of haloperidol on GABA-A R binding in a receptor-subtype specific manner. Our results show that exposure to haloperidol causes changes in α5GABA-A R predominantly in the dorsal CA1 and the nucleus accumbens. …”
Publicado 2020
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102908por Camara, Bienvenu Salim, Delamou, Alexandre, Grovogui, Fassou Mathias, de Kok, Bregje Christina, Benova, Lenka, El Ayadi, Alison Marie, Gerrets, Rene, Grietens, Koen Peeters, Delvaux, Thérèse“…This happens because they do not have access to good health services in a timely manner during labor and after giving birth. Worldwide, many interventions have been implemented to Increase the number of women giving birth in a health facility or receiving care from health professional after giving birth. …”
Publicado 2021
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102909por Fields, T., Patterson, M., Bremova-Ertl, T., Belcher, G., Billington, I., Churchill, G. C., Davis, W., Evans, W., Flint, S., Galione, A., Granzer, U., Greenfield, J., Karl, R., Kay, R., Lewi, D., Mathieson, T., Meyer, T., Pangonis, D., Platt, F. M., Tsang, L., Verburg, C., Factor, M., Strupp, M.“…The anchor tests are videoed in a standardized manner at each visit to capture all aspects related to the patient’s functional performance. …”
Publicado 2021
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102910“…Such an experimental design is named as a loosely controlled creativity experiment, which offers an approach to studying creativity in an ecologically valid manner. The validity of the loosely controlled creativity experiment could be verified through comparing its findings on phenomena that have been effectively studied by validated experimental research. …”
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102911por He, Xin, Sarafoglou, Kyriakie, Fechner, Patricia Y, Vogiatzi, Maria George, Imel, Erik Allen, Davis, Shanlee Marie, Sturgeon, Julia, Chan, Jean Lin, Farber, Robert, Auchus, Richard Joseph“…Conclusions: Following crinecerfont therapy, A4 and A4/T decreased in a dose-dependent manner in men with 21OHD. In contrast to reductions in T observed in women with 21OHD, T did not change consistently and rose in some men. …”
Publicado 2021
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102912por Hayes, Megan E., Hemsworth, Lauren M., Morrison, Rebecca S., Tilbrook, Alan J., Hemsworth, Paul H.“…We hypothesised that piglets handled in a positive manner and reared in loose farrowing and lactation pens with increased opportunity for interaction with their dam, greater space and more complexity in their physical environment have improved stress resilience than piglets reared in traditional farrowing crates with routine contact from stockpeople. …”
Publicado 2021
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102913por Cashman, Helen, Mayson, Eleni, Kliman, David, Vachalec, Sue, Bell, Jennifer, Milliken, Sam, Moore, John, Lavee, Orly, Withers, Barbara, Hamad, Nada“…Despite the travel restrictions, the hematology outreach services to Griffith were maintained through telemedicine reviews in a similar manner to the metropolitan service. Griffith rural hematology patients continue to undergo regular telemedicine reviews with monitoring of laboratory and imaging results through the EHR, receiving the same level of care as metropolitan patients. …”
Publicado 2020
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102914por Ludington, Jacob G, Ansari, Shabbir A, Schmaier, Alec A, Enjyoji, Keiichi, Nilsson-Payant, Benjamin E, Bram, Yaron, Chandar, Vasuretha, Borczuk, Alain, tenOever, Benjamin R, Schwartz, Robert E, Schulman, Sol“…TMEM16F is a ubiquitous phospholipid scramblase that mediates externalization of PS in a calcium-dependent manner. As SARS-CoV-2 ORF3a encodes a presumed cation channel with the ability to transport calcium, we hypothesized that ORF3a expression by infected host cells perturbs the cellular calcium rheostat, driving TMEM16F-dependent externalization of PS and enhancing procoagulant activity. …”
Publicado 2021
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102915por Wang, Li-Ting, Lin, Ming-Hong, Liu, Kwei-Yan, Chiou, Shyh-Shin, Wang, Shen-Nien, Chai, Chee-Yin, Tseng, Li-Wen, Chiou, Hsin-Ying Clair, Wang, Hsueh-Chun, Yokoyama, Kazunari K., Hsu, Shih-Hsien, Huang, Shau-Ku“…In fact, WLS was discovered to integrate a protein complex in N-glycan-dependent and WLS domain-selective manners, comprising ER stress sensors and lectin chaperones. …”
Publicado 2021
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102916“…The antegrade approach prevents plantar displacement of the distal metatarsal fragment during K-wire insertion continues with an exteriorization by the retrograde manner of the wire in the plantar region. The study said that no complications were identified related to using the type of treatment. …”
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102917“…The use of CCP MDT structures allows more nuanced access to different opinions in a safe supportive manner, allowing for sharing of ideas and concerns – allowing for supporting diverse expertise and insight. …”
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102918“…CONCLUSIONS: Based on cost modeling, a high-dose IV iron protocol could be integrated in large Canadian regional hemodialysis program in a cost saving manner. Programs implementing such a protocol should monitor IV iron and EPO use prospectively to determine if the trial protocol as applied in a real-world setting translates into cost savings.…”
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102919por Harmsen, Jan-Frieder, Wefers, Jakob, Doligkeit, Daniel, Schlangen, Luc, Dautzenberg, Bas, Rense, Pascal, van Moorsel, Dirk, Hoeks, Joris, Moonen-Kornips, Esther, Gordijn, Marijke C. M., van Marken Lichtenbelt, Wouter D., Schrauwen, Patrick“…CONCLUSIONS/INTERPRETATION: Together, these findings suggest that the indoor light environment modulates postprandial substrate handling, energy expenditure and thermoregulation of insulin-resistant volunteers in a time-of-day-dependent manner. TRIAL REGISTRATION: ClinicalTrials.gov NCT03829982. …”
Publicado 2022
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102920por Bowdridge, Elizabeth C., DeVallance, Evan, Garner, Krista L., Griffith, Julie A., Schafner, Kallie, Seaman, Madison, Engels, Kevin J., Wix, Kimberley, Batchelor, Thomas P., Goldsmith, William T., Hussain, Salik, Nurkiewicz, Timothy R.“…Overnight exposure of these hepatocytes to F1 plasma increased H(2)O(2) production capacity in a partially NF-κB dependent manner. Pregnant F1- nano-TiO(2) females exhibited estrogen disruption (12.12 ± 3.1 pg/ml vs. 29.81 ± 8.8 pg/ml sham-control) and vascular dysfunction similar to their directly exposed mothers. …”
Publicado 2022
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