Organic carbon monoxide prodrug, BW-CO-111, in protection against chemically-induced gastric mucosal damage

por Bakalarz, Dominik, Surmiak, Marcin, Yang, Xiaoxiao, Wójcik, Dagmara, Korbut, Edyta, Śliwowski, Zbigniew, Ginter, Grzegorz, Buszewicz, Grzegorz, Brzozowski, Tomasz, Cieszkowski, Jakub, Głowacka, Urszula, Magierowska, Katarzyna, Pan, Zhixiang, Wang, Binghe, Magierowski, Marcin
Publicado 2021

Ultra-short-course and intermittent TB47-containing oral regimens produce stable cure against Buruli ulcer in a murine model and prevent the emergence of resistance for Mycobacteri...

por Gao, Yamin, Hameed, H.M. Adnan, Liu, Yang, Guo, Lingmin, Fang, Cuiting, Tian, Xirong, Liu, Zhiyong, Wang, Shuai, Lu, Zhili, Islam, Md Mahmudul, Zhang, Tianyu
Publicado 2021

A multifunctional cross-validation high-throughput screening protocol enabling the discovery of new SHP2 inhibitors

por Song, Yihui, Zhao, Min, Wu, Yahong, Yu, Bin, Liu, Hong-Min
Publicado 2021

New possible silver lining for pancreatic cancer therapy: Hydrogen sulfide and its donors

por Hu, Xu, Xiao, Yan, Sun, Jianan, Ji, Bao, Luo, Shanshan, Wu, Bo, Zheng, Chao, Wang, Peng, Xu, Fanxing, Cheng, Keguang, Hua, Huiming, Li, Dahong
Publicado 2021

The poly(ADP-ribosyl)ation of BRD4 mediated by PARP1 promoted pathological cardiac hypertrophy

por Li, Zhenzhen, Guo, Zhen, Lan, Rui, Cai, Sidong, Lin, Zhirong, Li, Jingyan, Wang, Junjian, Li, Zhuoming, Liu, Peiqing
Publicado 2021

New guaiane-type sesquiterpenoid dimers from Artemisia atrovirens and their antihepatoma activity

por Su, Lihua, Zhang, Xintian, Ma, Yunbao, Geng, Changan, Huang, Xiaoyan, Hu, Jing, Li, Tianze, Tang, Shuang, Shen, Cheng, Gao, Zhen, Zhang, Xuemei, Chen, Ji-Jun
Publicado 2021

An optimized derivative of an endogenous CXCR4 antagonist prevents atopic dermatitis and airway inflammation

por Harms, Mirja, Habib, Monica M.W., Nemska, Simona, Nicolò, Antonella, Gilg, Andrea, Preising, Nico, Sokkar, Pandian, Carmignani, Sara, Raasholm, Martina, Weidinger, Gilbert, Kizilsavas, Gönül, Wagner, Manfred, Ständker, Ludger, Abadi, Ashraf H., Jumaa, Hassan, Kirchhoff, Frank, Frossard, Nelly, Sanchez-Garcia, Elsa, Münch, Jan
Publicado 2021

Allium victorialis L. Extracts Promote Activity of FXR to Ameliorate Alcoholic Liver Disease: Targeting Liver Lipid Deposition and Inflammation

por Cui, Zhen-Yu, Han, Xin, Jiang, Yu-Chen, Dou, Jia-Yi, Yao, Kun-Chen, Hu, Zhong-He, Yuan, Ming-Hui, Bao, Xiao-Xue, Zhou, Mei-Jie, Liu, Yue, Lian, Li-Hua, Zhang, Xian, Nan, Ji-Xing, Wu, Yan-Ling
Publicado 2021

Discovery of a subtype-selective, covalent inhibitor against palmitoylation pocket of TEAD3

por Lu, Tian, Li, Yong, Lu, Wenchao, Spitters, TWGM, Fang, Xueyu, Wang, Jun, Cai, Simian, Gao, Jing, Zhou, Yanting, Duan, Zhe, Xiong, Huan, Liu, Liping, Li, Qi, Jiang, Hualiang, Chen, Kaixian, Zhou, Hu, Lin, Hua, Feng, Huijin, Zhou, Bing, Antos, Christopher L., Luo, Cheng
Publicado 2021

The effect of curculigo orchioides (Xianmao) on kidney energy metabolism and the related mechanism in rats based on metabolomics

por Chen, Limei, Qu, Baohua, Wang, Hui, Liu, Hongning, Guan, Yongmei, Zhou, Juanqing, Zhang, Jiaqi
Publicado 2021

Baicalin induces ferroptosis in bladder cancer cells by downregulating FTH1

por Kong, Na, Chen, Xiaying, Feng, Jiao, Duan, Ting, Liu, Shuiping, Sun, Xueni, Chen, Peng, Pan, Ting, Yan, Lili, Jin, Ting, Xiang, Yu, Gao, Quan, Wen, Chengyong, Ma, Weirui, Liu, Wencheng, Zhang, Mingming, Yang, Zuyi, Wang, Wengang, Zhang, Ruonan, Chen, Bi, Xie, Tian, Sui, Xinbing, Tao, Wei
Publicado 2021

Bioengineered miR-124-3p prodrug selectively alters the proteome of human carcinoma cells to control multiple cellular components and lung metastasis in vivo

por Deng, Linglong, Petrek, Hannah, Tu, Mei-Juan, Batra, Neelu, Yu, Ai-Xi, Yu, Ai-Ming
Publicado 2021

[(18)F]MAGL-4-11 positron emission tomography molecular imaging of monoacylglycerol lipase changes in preclinical liver fibrosis models

por Shao, Tuo, Chen, Zhen, Rong, Jian, Belov, Vasily, Chen, Jiahui, Jeyarajan, Andre, Deng, Xiaoyun, Fu, Hualong, Yu, Qingzhen, Rwema, Steve H., Lin, Wenyu, Papisov, Mikhail, Josephson, Lee, Chung, Raymond T., Liang, Steven H.
Publicado 2022

Preclinical evaluation and pilot clinical study of [(18)F]AlF-labeled FAPI-tracer for PET imaging of cancer associated fibroblasts

por Hu, Kongzhen, Li, Junqi, Wang, Lijuan, Huang, Yong, Li, Li, Ye, Shimin, Han, Yanjiang, Huang, Shun, Wu, Hubing, Su, Jin, Tang, Ganghua
Publicado 2022

Prunus mira Koehne in Sichuan, China: Recorded History as a Medicine and Food, Modern Applications, Distribution, and Ethnobotanical Investigations

por Zhang, Jingwen, Chen, Wanyue, Sun, Weijun, Zhou, You, Li, Xiaoli, Zhang, Jing, Fan, Gang, Yin, Hongxiang, Qin, Ju, Yuan, Yongcui, Xu, Wei, Wang, Zhang
Publicado 2022

Molecular insights into AabZIP1-mediated regulation on artemisinin biosynthesis and drought tolerance in Artemisia annua

por Shu, Guoping, Tang, Yueli, Yuan, Mingyuan, Wei, Ning, Zhang, Fangyuan, Yang, Chunxian, Lan, Xiaozhong, Chen, Min, Tang, Kexuan, Xiang, Lien, Liao, Zhihua
Publicado 2022

Genome-wide analysis identify novel germline genetic variations in ADCY1 influencing platinum-based chemotherapy response in non-small cell lung cancer

por Mao, Chenxue, Chen, Juan, Zou, Ting, Zhou, Yuankang, Liu, Junyan, Li, Xi, Li, Xiangping, Li, Min, Pan, Pinhua, Zhuo, Wei, Gao, Yang, Hu, Shuo, Xiao, Desheng, Wu, Lin, Wang, Zhan, Xu, Heng, Yang, Wen, Xu, Yingjie, Xiao, Haihua, Hanada, Kazuhiko, Zhang, Wei, Zhou, Honghao, Yin, Jiye, Liu, Zhaoqian
Publicado 2022

Engineering a folic acid-decorated ultrasmall gemcitabine nanocarrier for breast cancer therapy: Dual targeting of tumor cells and tumor-associated macrophages

por Moharil, Pearl, Wan, Zhuoya, Pardeshi, Apurva, Li, Jiang, Huang, Haozhe, Luo, Zhangyi, Rathod, Sanjay, Zhang, Ziqian, Chen, Yuang, Zhang, Bei, Fernandez, Christian A., Sun, Jingjing, Li, Song
Publicado 2022

Design of a highly potent GLP-1R and GCGR dual-agonist for recovering hepatic fibrosis

por Song, Nazi, Xu, Hongjiao, Liu, Jiahua, Zhao, Qian, Chen, Hui, Yan, Zhibin, Yang, Runling, Luo, Zhiteng, Liu, Qi, Ouyang, Jianmei, Wu, Shuohan, Luo, Suijia, Ye, Shuyin, Lin, Runfeng, Sun, Xi, Xie, Junqiu, Lan, Tian, Wu, Zhongdao, Wang, Rui, Jiang, Xianxing
Publicado 2022

Crosstalk between CYP2E1 and PPARα substrates and agonists modulate adipose browning and obesity

por Zhang, Youbo, Yan, Tingting, Wang, Tianxia, Liu, Xiaoyan, Hamada, Keisuke, Sun, Dongxue, Sun, Yizheng, Yang, Yanfang, Wang, Jing, Takahashi, Shogo, Wang, Qiong, Krausz, Kristopher W., Jiang, Changtao, Xie, Cen, Yang, Xiuwei, Gonzalez, Frank J.
Publicado 2022