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  1. 68821
    por Elaiw, A. M., AlShamrani, N. H.
    Publicado 2021
    “…HIV causes acquired immunodeficiency syndrome (AIDS), while HTLV-I is the causative agent for adult T-cell leukemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP). Several mathematical models have been developed in the literature to describe the within-host dynamics of HIV and HTLV-I mono-infections. …”
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    Modeling and analysis of a within-host HIV/HTLV-I co-infection
  2. 68822
    “…Results showed high intracellular concentrations of GS-443902 suggestive of efficient conversion from RDV into the triphosphate form, and further supporting this clinical dosing regimen for the treatment of COVID-19. Mathematical drug–drug interaction liability predictions, based on in vitro and phase I data, suggest RDV has low potential for drug–drug interactions, as the impact of inducers or inhibitors on RDV disposition is minimized by the parenteral route of administration and extensive extraction. …”
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    Pharmacokinetic, Pharmacodynamic, and Drug-Interaction Profile of Remdesivir, a SARS-CoV-2 Replication Inhibitor
  3. 68823
    “…The PRO-ACT database, with outcome data from 23 international clinical ALS trials, served as historical control and mathematical reference for survival modeling. Imaging data as well as cytokine and cellular data from stem cell analysis were processed as biomarkers in a non-linear principal component analysis (NLPCA) to identify individual response. …”
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    Modeling and Bioinformatics Identify Responders to G-CSF in Patients With Amyotrophic Lateral Sclerosis
  4. 68824
    “…METHODS: We created a mathematical model using all incident TB disease cases during 2013–2017 reported to the National Tuberculosis Surveillance System that were classified using genotype-based methods or imputation as not attributed to recent TB transmission. …”
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    State-level prevalence estimates of latent tuberculosis infection in the United States by medical risk factors, demographic characteristics and nativity
  5. 68825
    “…Three studies used mathematical models to simulate single- or multiple-direction flights, and two of them showed that facemask (e.g., N95 respirator) use considerably reduced infection probability. …”
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    Hand hygiene and facemask use to prevent droplet-transmitted viral diseases during air travel: a systematic literature review
  6. 68826
    “…BACKGROUND: Graphs are mathematical structures widely used for expressing relationships among elements when representing biomedical and biological information. …”
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    GRAPES-DD: exploiting decision diagrams for index-driven search in biological graph databases
  7. 68827
    “…Despite the theoretical demonstration of HCV treatment-as-prevention in prison in mathematical modeling, limited empirical data exist. …”
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    Considering treatment-as-prevention scale-up for Australian prisons: a qualitative sub-study of expert stakeholders from the Australian ‘surveillance and treatment of prisoners with hepatitis C’ project (SToP-C)
  8. 68828
    “…Lumen volume was calculated mathematically as the voxel volume multiplied by the number of voxels with HU within a given range, defined as the lumen for each method, and compared with the IVUS-derived reference standard. …”
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    Coronary Artery Lumen Segmentation Using Location–Adaptive Threshold in Coronary Computed Tomographic Angiography: A Proof-of-Concept
  9. 68829
    “…We pioneered a tapering model to describe half-leaf symmetric distribution with mathematical approximation based on every measured leaf along developmental sequence, and evaluated the ratio of leaf basal part length to total length (called tipping leaf length ratio). …”
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    Half-leaf width symmetric distribution reveals buffering strategy of Cunninghamia lanceolata
  10. 68830
    “…Refractive index (RI) and gravimetric total solid (gTS) concentration of solubilised samples were determined for the three experimental groups. A mathematical equation was determined with the experimental data from the healthy group, in order to obtain calculated total solid concentration (cTS) from refractivity (R) values. …”
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    A simple and reliable refractometric method to determine the total solids concentration of the cervico-vaginal bovine mucus samples
  11. 68831
    “…Data for the model were extracted from literature. A mathematical model was developed in Microsoft Excel to assess the impact of strategies B and C in a standard population of 1 million subjects living in a strongyloidiasis endemic area. …”
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    Control programs for strongyloidiasis in areas of high endemicity: an economic analysis of different approaches
  12. 68832
    “…These contact rates can be utilized in mathematical models to assess transmission dynamics of infectious diseases in similar communities. …”
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    A cross-sectional study measuring contact patterns using diaries in an urban and a rural community in South Africa, 2018
  13. 68833
    “…In this work, the authors used mathematical models to identify the potential brain regions related to AD. …”
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    Predicting Brain Regions Related to Alzheimer's Disease Based on Global Feature
  14. 68834
    “…An optimum chromatographic method in the design space was calculated by mathematical and response surface methodology (RSM). …”
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    Analytical quality by design methodology for botanical raw material analysis: a case study of flavonoids in Genkwa Flos
  15. 68835
    “…Depletion of CD8(+) lymphocytes in controllers resulted in transient recrudescence of viremia, suggesting that the combination of cART and anti-α4β7 antibody treatment led to a state where ongoing immune responses kept the virus undetectable in the absence of treatment. A previous mathematical model of HIV infection and cART incorporates immune effector cell responses and exhibits the property of two different viral load set-points. …”
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    Mechanistic basis of post-treatment control of SIV after anti-α4β7 antibody therapy
  16. 68836
    por Daghriri, Talal, Ozmen, Ozlem
    Publicado 2021
    “…To assess the effectiveness of these policies, the system’s dynamics of the society needs to be analyzed, which is generally not possible with mathematical linear equations or Monte Carlo methods because human society is a complex adaptive system with continuous feedback loops. …”
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    Quantifying the Effects of Social Distancing on the Spread of COVID-19
  17. 68837
    “…In this study, we merged patient data from multiple hospitals in different countries and developed a type of mathematical formula called “nomogram” that combines MRI findings with other available patient data. …”
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    International Multi-Site Initiative to Develop an MRI-Inclusive Nomogram for Side-Specific Prediction of Extraprostatic Extension of Prostate Cancer
  18. 68838
    “…We develop here a [Formula: see text]-SVEIHQRD mathematical model able to simulate the possible impact of this type of variants and of the vaccines, together with the main mechanisms influencing the disease spread. …”
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    Modeling the impact of SARS-CoV-2 variants and vaccines on the spread of COVID-19
  19. 68839
    “…BACKGROUND: Mathematical models are needed for the design of breeding programs using genomic prediction. …”
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    Predicting the accuracy of genomic predictions
  20. 68840
    “…BACKGROUND: This work aimed to identify the mathematical model and ecological determinants of COVID-19 infection and mortality across different countries during the first six months of the pandemic. …”
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    Pattern and determinants of COVID-19 infection and mortality across countries: An ecological study
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