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69601“…To test this hypothesis, a mathematical model of the electrical action potential of rat SAN myocytes was modified to simulate the functional impact of age-induced changes on membrane ion channels and intracellular Ca(2+) handling as observed in Aging Study-1 and Aging Study-2. …”
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69602por Hoover, Christopher M, Rumschlag, Samantha L, Strgar, Luke, Arakala, Arathi, Gambhir, Manoj, de Leo, Giulio A, Sokolow, Susanne H, Rohr, Jason R, Remais, Justin V“…We incorporated these dose-response functions and environmentally relevant concentrations of agrochemicals into a mathematical model to estimate agrochemical effects on schistosomiasis transmission. …”
Publicado 2020
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69603“…Similarly, with IWD, there was a moderate correlation with LSE (=10.8 + IWD * 0.56 (r = 0.61, p < 0.0001)), and strong correlation with ITS (=9.2 + IWD * 0.67 (r = 0.75, p < 0.0001)), while a weak correlation was found with SCE (=11.2 + IWD * 0.2 (r = 0.32, p < 0.0033)). Mathematical formulae derived from the multiple regression showed that the body condition score (BCS) improved the relationship between IWD and OCL and the LSE, SCE and ITS, while the addition of body weight was associated with multicollinearity. …”
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69604por Iacobas, Dumitru A., Mgbemena, Victoria E., Iacobas, Sanda, Menezes, Kareena M., Wang, Huichen, Saganti, Premkumar B.“…GFP considers the transcriptome as a multi-dimensional mathematical object constrained by a dynamic set of expression controls and correlations among genes. …”
Publicado 2020
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69605“…While two levels are ideal for estimating AUC/MIC mathematically, the logistics and costs may outweigh the benefits of this approach. …”
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69606“…METHODS: We used a mathematical model adapted to the population and healthcare settings in Japan. …”
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69607“…We first propose a method that can map three-dimensional multi-story multi-exit buildings into a two-dimensional graph. Then, a mathematical optimization model is proposed to capture this time-aware and temperature-aware evacuation path problem in multi-story multi-exit buildings. …”
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69608por Baral, Stefan, Rao, Amrita, Twahirwa Rwema, Jean Olivier, Lyons, Carrie, Cevik, Muge, Kågesten, Anna E., Diouf, Daouda, Sohn, Annette H., Phaswana-Mafuya, Nancy, Kamarulzaman, Adeeba, Millett, Gregorio, Marcus, Julia L., Mishra, Sharmistha“…Empiric studies reporting original data collection or mathematical models were included, and available data synthesized by region. …”
Publicado 2021
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69609por Pepic, Ivana, Feldt, Robert, Ljungström, Lars, Torkar, Richard, Dalevi, Daniel, Maurin Söderholm, Hanna, Andersson, Lars-Magnus, Axelson-Fisk, Marina, Bohm, Katarina, Sjöqvist, Bengt Arne, Candefjord, Stefan“…The term artificial intelligence is viewed broadly, and a wide range of machine learning and mathematical models suitable as base for decision support will be evaluated. …”
Publicado 2021
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69610por Peirlinck, Mathias, Linka, Kevin, Sahli Costabal, Francisco, Bhattacharya, Jay, Bendavid, Eran, Ioannidis, John P.A., Kuhl, Ellen“…Here we use reported symptomatic case data in conjunction with antibody seroprevalence studies, a mathematical epidemiology model, and a Bayesian framework to infer the epidemiological characteristics of COVID-19. …”
Publicado 2020
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69611por Keeling, Matt J., Hill, Edward M., Gorsich, Erin E., Penman, Bridget, Guyver-Fletcher, Glen, Holmes, Alex, Leng, Trystan, McKimm, Hector, Tamborrino, Massimiliano, Dyson, Louise, Tildesley, Michael J.“…Government agencies are presently analysing how best to develop an exit strategy from these measures and to determine how the epidemic may progress once measures are lifted. Mathematical models are currently providing short and long term forecasts regarding the future course of the COVID-19 outbreak in the UK to support evidence-based policymaking. …”
Publicado 2021
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69612por Mannu, Rashmi, Karthikeyan, Vaithinathan, Velu, Nandakumar, Arumugam, Chandravadhana, Roy, Vellaisamy A. L., Gopalan, Anantha-Iyengar, Saianand, Gopalan, Sonar, Prashant, Lee, Kwang-Pill, Kim, Wha-Jung, Lee, Dong-Eun, Kannan, Venkatramanan“…Specifically, we have selected three different MNPs (NiFe(2)O(4), CoFe(2)O(4) and Fe(3)O(4)) coated with PEG for the MNFs and compared their variance in the loading/release efficacy of DOX, through experimental results fitting into mathematical models. DOX loading takes the order in the MNFs as CoFe(2)O(4) > NiFe(2)O(4) > Fe(3)O(4). …”
Publicado 2021
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69613por Manisty, Charlotte, Treibel, Thomas Alexander, Jensen, Melanie, Semper, Amanda, Joy, George, Gupta, Rishi K, Cutino-Moguel, Teresa, Andiapen, Mervyn, Jones, Jessica, Taylor, Stephen, Otter, Ashley, Pade, Corrina, Gibbons, Joseph, Lee, Jason, Bacon, Joanna, Thomas, Steve, Moon, Chris, Jones, Meleri, Williams, Dylan, Lambourne, Jonathan, Fontana, Marianna, Altmann, Daniel M, Boyton, Rosemary, Maini, Mala, McKnight, Aine, Chain, Benjamin, Noursadeghi, Mahdad, Moon, James C“…By 21 weeks’ follow-up, 31/143 (21.7%) anti-S1 and 6/150 (4.0%) anti-NP measurements reverted to negative. Mathematical modelling revealed faster clearance of anti-S1 compared to anti-NP (median half-life of 2.5 weeks versus 4.0 weeks), earlier transition to lower levels of antibody production (median of 8 versus 13 weeks), and greater reductions in relative antibody production rate after the transition (median of 35% versus 50%). …”
Publicado 2021
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69614por Diawara, Halimatou, Walker, Patrick, Cairns, Matt, Steinhardt, Laura C., Diawara, Fatou, Kamate, Beh, Duval, Laeticia, Sicuri, Elisa, Sagara, Issaka, Sadou, Aboubacar, Mihigo, Jules, Eckert, Erin, Dicko, Alassane, Conteh, Lesong“…Effectiveness estimates were based upon a published mathematical transmission model calibrated to local epidemiology, rainfall patterns and scale-up of interventions. …”
Publicado 2021
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69615“…DESIGN, SETTING, AND PARTICIPANTS: This economic evaluation of observational data used multivariable regression analysis and mathematical modeling of hospital encounter costs, controlling for patient demographic, clinical, and insurance characteristics, and compared encounters with and without secondary SUD diagnosis to statistically identify the total attributable cost of SUD. …”
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69616por Mitchell, Kate M., Dimitrov, Dobromir, Hughes, James P., Moore, Mia, Vittinghoff, Eric, Liu, Albert, Cohen, Myron S., Beyrer, Chris, Donnell, Deborah, Boily, Marie-Claude“…Surveillance data on HIV diagnoses or viral suppression could provide cheaper incidence estimates. We used mathematical modelling to evaluate whether these measures can replace HIV incidence measurement in C-RCTs. …”
Publicado 2020
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69617por Bartl, Thomas, Karacs, Jasmine, Kreuzinger, Caroline, Pfaffinger, Stephanie, Kendler, Jonatan, Ciocsirescu, Cristina, Wolf, Andrea, Reinthaller, Alexander, Meyer, Elias, Brandstetter, Maximilian, Postl, Magdalena, Langthaler, Eva, Braicu, Elena, Vergote, Ignace, Cunnea, Paula, Gourley, Charlie, Schmitt, Wolfgang D., Cacsire Castillo-Tong, Dan, Christoph, Grimm“…The present study therefore aimed to adapt a mathematical model, which used frequently available laboratory values to estimate growth rates of recurring tumors as an objectifiable surrogate of both therapy response and patient survival. …”
Publicado 2021
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69618por Koum Besson, Emilie S, Norris, Andy, Bin Ghouth, Abdulla S, Freemantle, Terri, Alhaffar, Mervat, Vazquez, Yolanda, Reeve, Chris, Curran, Patrick J, Checchi, Francesco“…Findings suggest a substantial, under-ascertained impact of COVID-19 in this urban Yemeni governorate and are broadly in line with previous mathematical modelling predictions, though our method cannot distinguish direct from indirect virus deaths. …”
Publicado 2021
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69619por Simonescu, Claudia Maria, Tătăruş, Alina, Culiţă, Daniela Cristina, Stănică, Nicolae, Ionescu, Ioana Alexandra, Butoi, Bogdan, Banici, Ana-Maria“…The optimal operating conditions of the CR and MO removal processes were established in batch experiments. The mathematical models used to describe the processes at equilibrium were Freundlich and Langmuir adsorption isotherms. (3) Results: Cobalt ferrite–chitosan composite has a lower specific surface area (S(BET)) and consequently a lower adsorption capacity than cobalt ferrite. …”
Publicado 2021
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69620por Booton, Ross D, Fu, Gengfeng, MacGregor, Louis, Li, Jianjun, Ong, Jason J, Tucker, Joseph D, Turner, Katherine ME, Tang, Weiming, Vickerman, Peter, Mitchell, Kate M“…METHODS: Regional data from China indicated that the number of MSM undergoing facility‐based HIV testing reduced by 59% during the COVID‐19 pandemic, alongside reductions in ART initiation (34%), numbers of all sexual partners (62%) and consistency of condom use (25%), but initial data indicated no change in viral suppression. A mathematical model of HIV transmission/treatment among MSM was used to estimate the impact of disruptions on HIV infections/HIV‐related deaths. …”
Publicado 2021
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