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141Publicado 1989“…One was a large-conductance ("maxi") K+ channel which was activated by intracellular calcium and/or depolarizing membrane voltages, and the other was a smaller-conductance K+ channel which exhibited at least two conductance levels and displayed pronounced inward rectification. …”
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142por Behnam, Babak, Bohorquez‐Chaux, Adriana, Castaneda‐Mendez, Oscar Fernando, Tsuji, Hiroyuki, Ishitani, Manabu, Becerra Lopez‐Lavalle, Luis Augusto“…The resulting method is suitable for use in mini, midi, and maxi preparations and rapidly achieves high total RNA yields (170–600 μg·g(−1)) using low‐cost chemicals and consumables and with minimal contamination from polysaccharides, polyphenols, proteins, and other secondary metabolites. …”
Publicado 2019
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143por Chiarelli, Nina, Krnc, Matjaž, Milanič, Martin, Pferschy, Ulrich, Pivač, Nevena, Schauer, Joachim“…The sum of profits of vertices/items assigned to one color/agent should be optimized in a maxi-min sense. We derive complexity and algorithmic results for this problem, which is a generalization of the classical Partition and Independent Set problems. …”
Publicado 2020
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144“…Recent clinical research revealed that infusion of BK(Ca) channel opener MaxiPost caused vasodilation, headache and migraine attack. …”
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146por Weber, Maxi, Schumacher, Sarah, Hannig, Wiebke, Barth, Jürgen, Lotzin, Annett, Schäfer, Ingo, Ehring, Thomas, Kleim, BirgitEnlace del recurso
Publicado 2021
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147“…METHODS: Exosomes derived from PRP(PRP-Exos) were isolated and purified using the exoEasy Maxi Kit and then identified and analyzed. Primary rabbit chondrocytes were isolated and treated with interleukin 1 beta (IL-1β) to establish the OA model in vitro. …”
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148por Stracka, Simone“…The trigger system plays a key role in selecting signal events and rejecting background, and is comprised of a hardware level (L0), reducing the rate to the maxi- mum at which the detector can be fully read out, and a High Level Trigger (HLT) -implemented in software and deployed on a farm of roughly 25000 parallel processing cores- responsible for reducing the rate to the 5 kHz which can be processed offline. …”
Publicado 2014
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151“…Structural studies have revealed that many members of the ferritin family can self-assemble into nano-cages of two types. Maxi-ferritins form hollow spheres with octahedral symmetry composed of twenty-four monomers. …”
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152por Mallajosyula, Vamsee, Ganjavi, Conner, Chakraborty, Saborni, McSween, Alana M., Pavlovitch-Bedzyk, Ana Jimena, Wilhelmy, Julie, Nau, Allison, Manohar, Monali, Nadeau, Kari C., Davis, Mark M.“…Here, we report the development of an improved multimeric αβ T cell staining reagent platform, with each maxi-ferritin “spheromer” displaying 12 peptide-MHC complexes. …”
Publicado 2021
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154por Cader, M. Zaeem, de Almeida Rodrigues, Rodrigo Pereira, West, James A., Sewell, Gavin W., Md-Ibrahim, Muhammad N., Reikine, Stephanie, Sirago, Giuseppe, Unger, Lukas W., Iglesias-Romero, Ana Belén, Ramshorn, Katharina, Haag, Lea-Maxie, Saveljeva, Svetlana, Ebel, Jana-Fabienne, Rosenstiel, Philip, Kaneider, Nicole C., Lee, James C., Lawley, Trevor D., Bradley, Allan, Dougan, Gordon, Modis, Yorgo, Griffin, Julian L., Kaser, ArthurEnlace del recurso
Publicado 2020
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155por Abenavoli, Alessandra, DiFrancesco, Mattia Lorenzo, Schroeder, Indra, Epimashko, Svetlana, Gazzarrini, Sabrina, Hansen, Ulf Peter, Thiel, Gerhard, Moroni, Anna“…“Fast” gating, analyzed by β distributions, is responsible for the negative slope conductance in the single-channel current–voltage curve at extreme potentials, like in MaxiK potassium channels, and can be explained by depletion-aggravated instability of the filter region. …”
Publicado 2009
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156por Wojtovich, Andrew P., Sherman, Teresa A., Nadtochiy, Sergiy M., Urciuoli, William R., Brookes, Paul S., Nehrke, Keith“…The canonical Ca(2+)-activated BK (or “maxi-K”) channel SLO1 was dispensable for both mitochondrial K(+) transport and APC in both organisms. …”
Publicado 2011
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157“…The other one is the peripherally acting agents that target soluble guanylate cyclase, Rho-kinase pathway, and Maxi-K channel, etc. Also, a variety of preclinical studies by the application of biotherapies in the concept of therapeutic angiogenesis or neural regeneration as well as anti-fibrosis to regenerate damaged erectile tissue have been reported. …”
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158“…Here, we review the recent findings related to the main chloride channels identified in astrocytes: the voltage-dependent ClC-2, the calcium-activated bestrophin, the volume-activated VRAC (volume-regulated anion channel) and the stress-activated Maxi-Cl(−). We discuss key aspects of channel biophysics and structure with a focus on their role in glial physiology and human disease.…”
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159por Li, Su-Jin, Zhang, Xuan, Lukeš, Julius, Li, Bi-Qi, Wang, Ju-Feng, Qu, Liang-Hu, Hide, Geoff, Lai, De-Hua, Lun, Zhao-Rong“…Kinetoplastid flagellates are known for several unusual features, one of which is their complex mitochondrial genome, known as kinetoplast (k) DNA, composed of mutually catenated maxi- and minicircles. Trypanosoma lewisi is a member of the Stercorarian group of trypanosomes which is, based on human infections and experimental data, now considered a zoonotic pathogen. …”
Publicado 2020
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160por González-Cota, Ana L., Santana-Calvo, Carmen, Servín-Vences, Rocío, Orta, Gerardo, Balderas, Enrique“…The mitochondrial BK(Ca) channel (mitoBK(Ca)) is a splice variant of plasma membrane BK(Ca) (Maxi-K, BK(Ca), Slo1, K(Ca)1.1). While a high-resolution structure of mitoBK(Ca) is not available yet, functional and structural studies of the plasma membrane BK(Ca) have provided important clues on the gating of the channel by voltage and Ca(2+), as well as the interaction with auxiliary subunits. …”
Publicado 2021
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