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2101por Coorey, Genevieve M, Neubeck, Lis, Usherwood, Timothy, Peiris, David, Parker, Sharon, Lau, Annie Y S, Chow, Clara, Panaretto, Kathryn, Harris, Mark, Zwar, Nicholas, Redfern, Julie“…ETHICS AND DISSEMINATION: Ethics approval has been received from the University of Sydney Human Research Ethics Committee and the Aboriginal Health and Medical Research Council (AH&MRC) of New South Wales. Results will be disseminated via scientific forums including peer-reviewed publications and national and international conferences. …”
Publicado 2017
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2102por Price, James R, Cole, Kevin, Bexley, Andrew, Kostiou, Vasiliki, Eyre, David W, Golubchik, Tanya, Wilson, Daniel J, Crook, Derrick W, Walker, A Sarah, Peto, Timothy E A, Llewelyn, Martin J, Paul, John“…FUNDING: UK Medical Research Council, Wellcome Trust, Biotechnology and Biological Sciences Research Council, UK National Institute for Health Research, and Public Health England.…”
Publicado 2017
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2103por Roberts, Shelley, McInnes, Elizabeth, Bucknall, Tracey, Wallis, Marianne, Banks, Merrilyn, Chaboyer, Wendy“…Our team developed and tested a complex intervention, a pressure ulcer prevention care bundle promoting patient participation in care, in a cluster-randomised trial. The UK Medical Research Council recommends process evaluation of complex interventions to provide insight into why they work or fail and how they might be improved. …”
Publicado 2017
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2104por Chaplin, Emma, Hewitt, Stacey, Apps, Lindsay, Bankart, John, Pulikottil-Jacob, Ruth, Boyce, Sally, Morgan, Mike, Williams, Johanna, Singh, Sally“…PARTICIPANTS: 103 patients were recruited to the study and randomised: 52 to conventional rehabilitation (mean (±SD) age 66 (±8) years, Medical Research Council (MRC) 3 (IQR2–4)); 51 to the web arm (mean (±SD) age 66 (±10) years, MRC 3 (IQR2–4)). …”
Publicado 2017
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2105por Boeck, Lucas, Soriano, Joan B., Brusse-Keizer, Marjolein, Blasi, Francesco, Kostikas, Konstantinos, Boersma, Wim, Milenkovic, Branislava, Louis, Renaud, Lacoma, Alicia, Djamin, Remco, Aerts, Joachim, Torres, Antoni, Rohde, Gernot, Welte, Tobias, Martinez-Camblor, Pablo, Rakic, Janko, Scherr, Andreas, Koller, Michael, van der Palen, Job, Marin, Jose M., Alfageme, Inmaculada, Almagro, Pere, Casanova, Ciro, Esteban, Cristobal, Soler-Cataluña, Juan J., de-Torres, Juan P., Miravitlles, Marc, Celli, Bartolome R., Tamm, Michael, Stolz, Daiana“…Using a mixed clinical and statistical approach, body mass index (B), severe acute exacerbations of COPD frequency (AE), modified Medical Research Council dyspnoea severity (D) and copeptin (C) were identified as the most suitable simplified marker combination. 0, 1 or 2 points were assigned to each parameter and totalled to B-AE-D or B-AE-D-C. …”
Publicado 2016
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2106por Brett, Jonathan, Elshaug, Adam G., Bhatia, R. Sacha, Chalmers, Kelsey, Badgery-Parker, Tim, Pearson, Sallie-Anne“…The protocol described herein outlines a program of research funded by Australia’s National Health and Medical Research Council to select and quantify low-value prescribing practices within Australian routinely collected health data. …”
Publicado 2017
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2107por de Oliveira, Hugo Goulart, Cruz, Fernanda Ferreira, Antunes, Mariana Alves, de Macedo Neto, Amarilio Vieira, Oliveira, Guilherme Augusto, Svartman, Fabio Munhoz, Borgonovo, Tamara, Rebelatto, Carmen Lucia Kuniyoshi, Weiss, Daniel J., Brofman, Paulo Roberto Slud, Morales, Marcelo Marcos, Lapa e Silva, José Roberto, Rocco, Patricia Rieken Macedo“…EBV + MSC patients presented decreased levels of circulating C‐reactive protein at 30 and 90 days, as well as BODE (Body mass index, airway Obstruction, Dyspnea, and Exercise index) and MMRC (Modified Medical Research Council) scores. Thus, combined use of EBV and MSCs appears to be safe in patients with severe COPD, providing a basis for subsequent investigations using MSCs as concomitant therapy. …”
Publicado 2016
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2108“…Mean (SD) age was 68 (7) years, post-bronchdilator FEV(1) 44.2 (15.5) % predicted, and Medical Research Council (MRC) dyspnea score 3.8 (0.41). We met feasibility objectives for action plan and advance care planning completion. …”
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2109por Katikireddi, Srinivasa Vittal, Whitley, Elise, Lewsey, Jim, Gray, Linsay, Leyland, Alastair H“…INTERPRETATION: Disadvantaged social groups have greater alcohol-attributable harms compared with individuals from advantaged areas for given levels of alcohol consumption, even after accounting for different drinking patterns, obesity, and smoking status at the individual level. FUNDING: Medical Research Council, NHS Research Scotland, Scottish Government Chief Scientist Office.…”
Publicado 2017
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2110por Payne, Ruth O., Silk, Sarah E., Elias, Sean C., Milne, Kathryn H., Rawlinson, Thomas A., Llewellyn, David, Shakri, A. Rushdi, Jin, Jing, Labbé, Geneviève M., Edwards, Nick J., Poulton, Ian D., Roberts, Rachel, Farid, Ryan, Jørgensen, Thomas, Alanine, Daniel G.W., de Cassan, Simone C., Higgins, Matthew K., Otto, Thomas D., McCarthy, James S., de Jongh, Willem A., Nicosia, Alfredo, Moyle, Sarah, Hill, Adrian V.S., Berrie, Eleanor, Chitnis, Chetan E., Lawrie, Alison M., Draper, Simon J.“…Support was provided by the UK Medical Research Council, UK National Institute of Health Research Oxford Biomedical Research Centre, and the Wellcome Trust.…”
Publicado 2017
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2111por Bourne, Simon, DeVos, Ruth, North, Malcolm, Chauhan, Anoop, Green, Ben, Brown, Thomas, Cornelius, Victoria, Wilkinson, Tom“…PARTICIPANTS: 90 patients with a diagnosis of chronic obstructive pulmonary disease (COPD), modified Medical Research Council score of 2 or greater referred for pulmonary rehabilitation (PR), randomised in a 2:1 ratio to online (n=64) or face-to-face PR (n=26). …”
Publicado 2017
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2112“…Significant differences between the four phenotypes were found regarding age; sex; body mass index; FEV(1); body mass index, airflow obstruction, dyspnea, and exercise capacity (BODE)/body mass index, airflow obstruction, dyspnea and exacerbations (BODEx) index; modified Medical Research Council dyspnea scale; respiratory symptoms; comorbidi-ties; hospitalizations; and exacerbations in the last year. …”
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2113por Lim, Jeong Uk, Lee, Jae Ha, Kim, Ju Sang, Hwang, Yong Il, Kim, Tae-Hyung, Lim, Seong Yong, Yoo, Kwang Ha, Jung, Ki-Suck, Kim, Young Kyoon, Rhee, Chin Kook“…Medical history including age, sex, St George’s Respiratory Questionnaire (SGRQ-C), the modified Medical Research Council (mMRC) dyspnea scale, and post-bronchodilator forced expiratory volume in 1 second (FEV(1)) were evaluated. …”
Publicado 2017
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2114“…During the baseline visit, patients performed pulmonary function tests and dyspnea evaluation using the modified Medical Research Council (mMRC) scale. Partial patients underwent quantitative computerized tomography scans under physicians’ recommendations, and emphysematous changes were assessed using the emphysema index (EI; low attenuation area [LAA]% −950). …”
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2115por Tonelli, Roberto, Cocconcelli, Elisabetta, Lanini, Barbara, Romagnoli, Isabella, Florini, Fabio, Castaniere, Ivana, Andrisani, Dario, Cerri, Stefania, Luppi, Fabrizio, Fantini, Riccardo, Marchioni, Alessandro, Beghè, Bianca, Gigliotti, Francesco, Clini, Enrico M.“…Lung function, incremental and endurance cyclo-ergometry, Six Minutes Walking Distance (6MWD), chronic dyspnea (Medical Research Council scale-MRC) and quality of life (St. …”
Publicado 2017
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2116por Márta, Katalin, Szabó, Anikó N, Pécsi, Dániel, Varjú, Péter, Bajor, Judit, Gódi, Szilárd, Sarlós, Patrícia, Mikó, Alexandra, Szemes, Kata, Papp, Mária, Tornai, Tamás, Vincze, Áron, Márton, Zsolt, Vincze, Patrícia A, Lankó, Erzsébet, Szentesi, Andrea, Molnár, Tímea, Hágendorn, Roland, Faluhelyi, Nándor, Battyáni, István, Kelemen, Dezső, Papp, Róbert, Miseta, Attila, Verzár, Zsófia, Lerch, Markus M, Neoptolemos, John P, Sahin-Tóth, Miklós, Petersen, Ole H, Hegyi, Péter“…ETHICS AND DISSEMINATION: The study has been approved by the relevant organisation, the Scientific and Research Ethics Committee of the Hungarian Medical Research Council (55961-2/2016/EKU). This study will provide evidence as to whether early high energy nutritional support is beneficial in the clinical management of AP. …”
Publicado 2017
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2117por Labarca, Gonzalo, Bustamante, Andrea, Valdivia, Gonzalo, Díaz, Rodrigo, Huete, Álvaro, Mac Nab, Paul, Mendoza, Laura, Leppe, Jaime, Lisboa, Carmen, Saldías, Fernando, Díaz, Orlando“…Two hundred and forty participants will be enrolled into four strata, according to normal spirometry or mild spirometric obstruction and presence or not of dyspnoea modified Medical Research Council score ≥1. The primary outcome will be the difference between dyspnoeic and non-dyspnoeic individuals on the 6-min walk test performance, regardless of their spirometry results. …”
Publicado 2017
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2118por Stafford, Lesley, Sinclair, Michelle, Turner, Jane, Newman, Louise, Wakefield, Claire, Krishnasamy, Mei, Mann, G. Bruce, Gilham, Leslie, Mason, Kylie, Rauch, Paula, Cannell, Julia, Schofield, Penelope“…METHODS/DESIGN: This study comprises two phases using the UK Medical Research Council framework for developing complex interventions. …”
Publicado 2017
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2119por Li, Wen-Jun, He, Li-Yue, Chen, Shan-Lin, Lyu, Yan-Wei, Wang, Shu-Feng, Yong, Yang, Tian, Wen, Tian, Guang-Lei, Gu, Yu-Dong“…Muscle strength and sensory recovery were considered to be effective only when the scores on the United Kingdom Medical Research Council scale were equal to or higher than M3 and S3, respectively. …”
Publicado 2017
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2120por Lollert, André, Stihl, Clemens, Hötker, Andreas M., Mengel, Eugen, König, Jochem, Laudemann, Katharina, Gökce, Seyfullah, Düber, Christoph, Staatz, Gundula“…Measurements derived from the quantitative method correlated well with Medical Research Council scores of muscle strength, with moderate correlations found for the 6-minute walk test, the 4-step stair climb test, and spirometry in the supine position. …”
Publicado 2018
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