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2441por Bennett, James E, Li, Guangquan, Foreman, Kyle, Best, Nicky, Kontis, Vasilis, Pearson, Clare, Hambly, Peter, Ezzati, Majid“…FUNDING: UK Medical Research Council and Public Health England.…”
Publicado 2015
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2442por Leong, Trevor, Smithers, B Mark, Michael, Michael, Gebski, Val, Boussioutas, Alex, Miller, Danielle, Simes, John, Zalcberg, John, Haustermans, Karin, Lordick, Florian, Schuhmacher, Christoph, Swallow, Carol, Darling, Gail, Wong, Rebecca“…Following publication of the US Intergroup 0116 and UK Medical Research Council MAGIC trials, there are now two standards of care for adjuvant therapy in resectable gastric cancer, at least in the Western world: postoperative chemoradiotherapy and perioperative epirubicin/cisplatin/fluorouracil (ECF) chemotherapy. …”
Publicado 2015
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2443por Gasparrini, Antonio, Guo, Yuming, Hashizume, Masahiro, Lavigne, Eric, Zanobetti, Antonella, Schwartz, Joel, Tobias, Aurelio, Tong, Shilu, Rocklöv, Joacim, Forsberg, Bertil, Leone, Michela, De Sario, Manuela, Bell, Michelle L, Guo, Yue-Liang Leon, Wu, Chang-fu, Kan, Haidong, Yi, Seung-Muk, de Sousa Zanotti Stagliorio Coelho, Micheline, Saldiva, Paulo Hilario Nascimento, Honda, Yasushi, Kim, Ho, Armstrong, Ben“…FUNDING: UK Medical Research Council.…”
Publicado 2015
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2444por Sinnott, Carol, Mercer, Stewart W., Payne, Rupert A., Duerden, Martin, Bradley, Colin P., Byrne, Molly“…Here, we describe how we have used results from a review of previous research, original research of our own and the Behaviour Change Wheel to develop an intervention to improve medication management in multimorbidity by general practitioners (GPs), within the overarching UK Medical Research Council guidance on complex interventions. …”
Publicado 2015
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2445por White, Michael T, Verity, Robert, Griffin, Jamie T, Asante, Kwaku Poku, Owusu-Agyei, Seth, Greenwood, Brian, Drakeley, Chris, Gesase, Samwel, Lusingu, John, Ansong, Daniel, Adjei, Samuel, Agbenyega, Tsiri, Ogutu, Bernhards, Otieno, Lucas, Otieno, Walter, Agnandji, Selidji T, Lell, Bertrand, Kremsner, Peter, Hoffman, Irving, Martinson, Francis, Kamthunzu, Portia, Tinto, Halidou, Valea, Innocent, Sorgho, Hermann, Oneko, Martina, Otieno, Kephas, Hamel, Mary J, Salim, Nahya, Mtoro, Ali, Abdulla, Salim, Aide, Pedro, Sacarlal, Jahit, Aponte, John J, Njuguna, Patricia, Marsh, Kevin, Bejon, Philip, Riley, Eleanor M, Ghani, Azra C“…FUNDING: UK Medical Research Council.…”
Publicado 2015
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2446por McLoughlin, Kathleen, Rhatigan, Jim, McGilloway, Sinead, Kellehear, Allan, Lucey, Michael, Twomey, Feargal, Conroy, Marian, Herrera-Molina, Emillio, Kumar, Suresh, Furlong, Mairead, Callinan, Joanne, Watson, Max, Currow, David, Bailey, Christopher“…DESIGN: The INSPIRE study will be conducted within the Medical Research Council (MRC) Framework for the Evaluation of Complex Interventions (Phases 0–2) and includes an exploratory two-arm delayed intervention randomised controlled trial. …”
Publicado 2015
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2447por Turner, Paul J, Southern, Jo, Andrews, Nick J, Miller, Elizabeth, Erlewyn-Lajeunesse, Michel“…PJT and MEL had support from the Department of Health for the submitted work; PJT has received research grants from the Medical Research Council and NIHR. No additional data available. …”
Publicado 2015
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2448por Horne, Margaret A, Flemming, Kelly D, Su, I-Chang, Stapf, Christian, Jeon, Jin Pyeong, Li, Da, Maxwell, Susanne S, White, Philip, Christianson, Teresa J, Agid, Ronit, Cho, Won-Sang, Oh, Chang Wan, Wu, Zhen, Zhang, Jun-Ting, Kim, Jeong Eun, ter Brugge, Karel, Willinsky, Robert, Brown, Robert D, Murray, Gordon D, Salman, Rustam Al-Shahi“…FUNDING: UK Medical Research Council, Chief Scientist Office of the Scottish Government, and UK Stroke Association.…”
Publicado 2016
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2449por Fischer, Arabella, Spiegl, Matthias, Altmann, Klaus, Winkler, Andreas, Salamon, Anna, Themessl-Huber, Michael, Mouhieddine, Mohamed, Strasser, Eva Maria, Schiferer, Arno, Paternostro-Sluga, Tatjana, Hiesmayr, Michael“…The primary outcomes were MLT measured by ultrasonography and muscle strength evaluated with the Medical Research Council (MRC) scale. The secondary functional outcomes were average mobility level, FIM score, Timed Up and Go Test and SF-12 health survey. …”
Publicado 2016
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2450“…The largest funder was the United States National Institutes of Health ($26.1 billion), followed by the European Commission ($3.7 billion), and the United Kingdom Medical Research Council ($1.3 billion). The largest philanthropic funder was the Wellcome Trust ($909.1 million), the largest funder of health research through official development assistance was USAID ($186.4 million), and the largest multilateral funder was the World Health Organization ($135.0 million). …”
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2451“…Data were collected through interviewer administered structured questions derived from British Medical Research Council (BMRC) adult respiratory symptom assessment questions and observational check lists for the assessment of dust exposure, hygienic practices and use of personal protective equipments. …”
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2452por Harris, Fiona M., Maxwell, Margaret, O’Connor, Rory, Coyne, James C., Arensman, Ella, Coffey, Claire, Koburger, Nicole, Gusmão, Ricardo, Costa, Susana, Székely, András, Cserhati, Zoltan, McDaid, David, van Audenhove, Chantal, Hegerl, Ulrich“…BACKGROUND: The Medical Research Council (MRC) Framework for complex interventions highlights the need to explore interactions between components of complex interventions, but this has not yet been fully explored within complex, non-pharmacological interventions. …”
Publicado 2016
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2453por Boots, Lizzy MM, de Vugt, Marjolein E, Withagen, Hanneke EJ, Kempen, Gertrudis IJM, Verhey, Frans RJ“…METHODS: Based on the Medical Research Council (MRC) framework for the development and evaluation of complex interventions, a stepwise approach was adopted to explore potential user needs and develop and validate the content by means of (1) focus group discussions with dementia caregivers (N=28), (2) interviews with dementia care professionals (N=11), and (3) individual think-aloud usability tests with EDC (N=2) and experts (N=2). …”
Publicado 2016
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2454por Haahr, Martha Kirstine, Jensen, Charlotte Harken, Toyserkani, Navid Mohamadpour, Andersen, Ditte Caroline, Damkier, Per, Sørensen, Jens Ahm, Lund, Lars, Sheikh, Søren Paludan“…FUNDING: Danish Medical Research Council, Odense University Hospital and the Danish Cancer Society.…”
Publicado 2016
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2455por Hurley, Deirdre A., Murphy, Laura Currie, Hayes, David, Hall, Amanda M., Toomey, Elaine, McDonough, Suzanne M., Lonsdale, Chris, Walsh, Nicola E., Guerin, Suzanne, Matthews, James“…BACKGROUND: The Medical Research Council framework provides a useful general approach to designing and evaluating complex interventions, but does not provide detailed guidance on how to do this and there is little evidence of how this framework is applied in practice. …”
Publicado 2016
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2456por Sousa, Ana R, Riley, John H, Church, Alison, Zhu, Chang-Qing, Punekar, Yogesh S, Fahy, William A“…Patients were symptomatic (modified Medical Research Council Dyspnoea Scale score ⩾2), despite receiving ICS/LABA (fluticasone propionate/salmeterol (FP/SAL, branded) 500/50 mcg, budesonide/formoterol (BD/FOR, branded) 200/6 mcg or 400/12 mcg, or other ICS/LABAs) ⩾30 days before the run-in (7±2 days). …”
Publicado 2016
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2457por Ammerlaan, Judy W, Mulder, Olga K, de Boer-Nijhof, Nienke C, Maat, Bertha, Kruize, Aike A, van Laar, Jaap, van Os-Medendorp, Harmieke, Geenen, Rinie“…The research team followed the new guidance by the Medical Research Council (MRC) for developing and evaluating complex interventions as a guide for the design of the intervention. …”
Publicado 2016
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2458por Avery, Leah, Charman, Sarah J., Taylor, Louise, Flynn, Darren, Mosely, Kylie, Speight, Jane, Lievesley, Matthew, Taylor, Roy, Sniehotta, Falko F., Trenell, Michael I.“…METHODS: In accordance with the Medical Research Council Framework for the Development and Evaluation of Complex Interventions, a four-stage systematic development process was undertaken: (1) exploratory work involving interviews and workshop discussions identified training needs of healthcare professionals and support needs of adults with type 2 diabetes; (2) a systematic review with meta- and moderator analyses identified behaviour change techniques and optimal intervention intensity and duration; (3) usability testing identified strategies to increase implementation of the intervention in primary care and (4) an open pilot study in two primary care practices facilitated intervention optimisation. …”
Publicado 2016
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2459por Muth, Christiane, Harder, Sebastian, Uhlmann, Lorenz, Rochon, Justine, Fullerton, Birgit, Güthlin, Corina, Erler, Antje, Beyer, Martin, van den Akker, Marjan, Perera, Rafael, Knottnerus, André, Valderas, Jose M, Gerlach, Ferdinand M, Haefeli, Walter E“…In accordance with the Medical Research Council guidance on developing and evaluating complex interventions, we prepared for the main study by testing the feasibility of the intervention and study design in a cluster randomised pilot study. …”
Publicado 2016
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2460por Wellings, Kaye, Palmer, Melissa J, Geary, Rebecca S, Gibson, Lorna J, Copas, Andrew, Datta, Jessica, Glasier, Anna, Scott, Rachel H, Mercer, Catherine H, Erens, Bob, Macdowall, Wendy, French, Rebecca S, Jones, Kyle, Johnson, Anne M, Tanton, Clare, Wilkinson, Paul“…INTERPRETATION: A sustained, multifaceted policy intervention involving health and education agencies, alongside other social and educational changes, has probably contributed to a substantial and accelerating decline in conceptions in women younger than 18 years in England since the late 1990s. FUNDING: Medical Research Council, Wellcome Trust, Economic and Social Research Council, and Department of Health.…”
Publicado 2016
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