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2501por Mehra, Sumit, Visser, Bart, Dadema, Tessa, van den Helder, Jantine, Engelbert, Raoul HH, Weijs, Peter JM, Kröse, Ben JA“…METHODS: The Medical Research Council framework was used to develop the blended intervention. …”
Publicado 2018
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2502“…In addition, with higher scores of the CAT and CCQ, subjects displayed more impairment in lung function, higher levels on modified Medical Research Council, and higher exacerbation rates in the last year (P<0.001). …”
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2503por Fewings, Eleanor, Larionov, Alexey, Redman, James, Goldgraben, Mae A, Scarth, James, Richardson, Susan, Brewer, Carole, Davidson, Rosemarie, Ellis, Ian, Evans, D Gareth, Halliday, Dorothy, Izatt, Louise, Marks, Peter, McConnell, Vivienne, Verbist, Louis, Mayes, Rebecca, Clark, Graeme R, Hadfield, James, Chin, Suet-Feung, Teixeira, Manuel R, Giger, Olivier T, Hardwick, Richard, di Pietro, Massimiliano, O'Donovan, Maria, Pharoah, Paul, Caldas, Carlos, Fitzgerald, Rebecca C, Tischkowitz, Marc“…FUNDING: UK Medical Research Council (Sackler programme), European Research Council under the European Union's Seventh Framework Programme (2007–13), National Institute for Health Research Cambridge Biomedical Research Centre, Experimental Cancer Medicine Centres, and Cancer Research UK.…”
Publicado 2018
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2504por Leidy, Nancy K, Martinez, Fernando J, Malley, Karen G, Mannino, David M, Han, MeiLan K, Bacci, Elizabeth D, Brown, Randall W, Houfek, Julia F, Labaki, Wassim W, Make, Barry J, Meldrum, Catherine A, Quezada, Wilson, Rennard, Stephen, Thomashow, Byron, Yawn, Barbara P“…The modified Medical Research Council (mMRC) dyspnea scale and COPD Assessment Test (CAT™) were used to evaluate symptoms and health status. …”
Publicado 2018
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2505por Davis, Katrina A. S., Coleman, Jonathan R. I., Adams, Mark, Allen, Naomi, Breen, Gerome, Cullen, Breda, Dickens, Chris, Fox, Elaine, Graham, Nick, Holliday, Jo, Howard, Louise M., John, Ann, Lee, William, McCabe, Rose, McIntosh, Andrew, Pearsall, Robert, Smith, Daniel J., Sudlow, Cathie, Ward, Joey, Zammit, Stan, Hotopf, Matthew“…C.S. received grants from the Medical Research Council and Wellcome Trust during the study, and is the Chief Scientist for UK Biobank. …”
Publicado 2018
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2506por Wei, Xia, Yu, Nan, Ding, Qi, Ren, Jingting, Mi, Jiuyun, Bai, Lu, Li, Jianying, Qi, Min, Guo, Youmin“…RESULTS: Compared with the non-carbon dioxide retention group, the group with carbon dioxide retention had a higher number of hospitalizations in the previous 12 months (p = 0.013), higher modified Medical Research Council (mMRC) dyspnea scores (p = 0.034), lower arterial oxygen pressure (p = 0.018), worse pulmonary function (forced expiratory volume in one second/forced vital capacity [FEV(1)/FVC; p < 0.001], FEV(1)%pred [p < 0.001], Z5%pred [p = 0.004], R5%pred [p = 0.008], R5-R20 [p = 0.009], X5 [p = 0.022], and Ax [p = 0.011]), more severe lung damage (such as increased lung volume [p = 0.011], more emphysema range [p = 0.007], and lower mean lung density [p = 0.043]). …”
Publicado 2018
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2507por Islam, Badrul, Islam, Zhahirul, Rahman, Shafiqur, Endtz, Hubert P, Vos, Margreet C, van der Jagt, Mathieu, van Doorn, Peter A, Jacobs, Bart C, Mohammad, Quazi Deen“…RESULTS: Median patient age 33 years (IQR 23–46; range 18–55); 13 (65%) were male. Median Medical Research Council (MRC) sum score was 20 (IQR 0–29; range 0–36); three (15%) patients required mechanical ventilation. …”
Publicado 2018
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2508“…METHODS: This integrated post hoc analysis of four 12-week, randomized, double-blind trials (NCT01772134, NCT01772147, NCT01957163, NCT02119286) compared UMEC 62.5 µg with placebo added to open-label ICS/LABA in symptomatic patients with COPD (modified Medical Research Council dyspnea scale score ≥ 2). A clinically important deterioration (CID) was defined as: a decrease from baseline of ≥ 100 mL in trough forced expiratory volume in 1 s (FEV(1)), an increase from baseline of ≥ 4 units in St George’s Respiratory Questionnaire (SGRQ) total score, or a moderate/severe exacerbation. …”
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2509por Kent, Seamus, Green, Jane, Reeves, Gillian, Beral, Valerie, Gray, Alastair, Jebb, Susan A, Cairns, Benjamin J, Mihaylova, Borislava“…FUNDING: Cancer Research UK; Medical Research Council; National Institute for Health Research.…”
Publicado 2017
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2510por Caudell, Mark A, Mair, Colette, Subbiah, Murugan, Matthews, Louise, Quinlan, Robert J, Quinlan, Marsha B, Zadoks, Ruth, Keyyu, Julius, Call, Douglas R“…FUNDING: US National Science Foundation; Biotechnology and Biological Sciences Research Council, UK Medical Research Council; and the Allen School.…”
Publicado 2018
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2511por Commons, Robert J, Simpson, Julie A, Thriemer, Kamala, Hossain, Mohammad S, Douglas, Nicholas M, Humphreys, Georgina S, Sibley, Carol H, Guerin, Philippe J, Price, Ric N“…FUNDING: Australian National Health and Medical Research Council, Royal Australasian College of Physicians, Wellcome Trust, and Bill & Melinda Gates Foundation.…”
Publicado 2019
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2512por Smyth, E C, Nyamundanda, G, Cunningham, D, Fontana, E, Ragulan, C, Tan, I B, Lin, S J, Wotherspoon, A, Nankivell, M, Fassan, M, Lampis, A, Hahne, J C, Davies, A R, Lagergren, J, Gossage, J A, Maisey, N, Green, M, Zylstra, J L, Allum, W H, Langley, R E, Tan, P, Valeri, N, Sadanandam, A“…PATIENTS AND METHODS: The Medical Research Council Adjuvant Gastric Infusional Chemotherapy (MAGIC) trial (n = 202 with high quality RNA) samples treated with perioperative chemotherapy were profiled for a custom gastric cancer gene panel using the NanoString platform. …”
Publicado 2018
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2513por Harrison, B. L., Ogara, C., Gladstone, M., Carrol, E. D., Dusabe-Richards, J., Medina-Lara, A., Ditai, J., Weeks, A. D.“…TRIAL FUNDING: Medical Research Council/ Wellcome Trust/ DfID (Global Health Trials Scheme).…”
Publicado 2019
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2514por Simpson, Rachel F, Hermon, Carol, Liu, Bette, Green, Jane, Reeves, Gillian K, Beral, Valerie, Floud, Sarah“…FUNDING: UK Medical Research Council and Cancer Research UK.…”
Publicado 2018
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2515por Dimitropoulos, Yvonne, Blinkhorn, Anthony, Irving, Michelle, Skinner, John, Naoum, Steven, Holden, Alexander, Masoe, Angela, Rambaldini, Boe, Christie, Vita, Spallek, Heiko, Gwynne, Kylie“…This study protocol has been approved by the NSW Aboriginal Health and Medical Research Council and the NSW State Education Research Application Process. …”
Publicado 2019
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2516por Freeman, Daniel, Lister, Rachel, Waite, Felicity, Yu, Ly-Mee, Slater, Mel, Dunn, Graham, Clark, David“…The trial is funded by the Medical Research Council Developmental Pathway Funding Scheme. …”
Publicado 2019
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2517por Gandolfi, Marialuisa, Valè, Nicola, Dimitrova, Eleonora Kirilova, Mazzoleni, Stefano, Battini, Elena, Filippetti, Mirko, Picelli, Alessandro, Santamato, Andrea, Gravina, Michele, Saltuari, Leopold, Smania, Nicola“…Secondary outcomes were the Fugl-Meyer Assessment Scale (FMA) and the Medical Research Council Scale (MRC). The electromyographic activity of 5 UL muscles during the “hand-to-mouth” task was explored only in the experimental group and 14 healthy age-matched controls using a surface Electromyography (EMGs). …”
Publicado 2019
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2518por Vousden, Nicola, Lawley, Elodie, Nathan, Hannah L, Seed, Paul T, Gidiri, Muchabayiwa Francis, Goudar, Shivaprasad, Sandall, Jane, Chappell, Lucy C, Shennan, Andrew H“…FUNDING: Newton Fund Global Research Programme: UK Medical Research Council; Department of Biotechnology, Ministry of Science & Technology, Government of India; and UK Department of International Development.…”
Publicado 2019
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2519“…Interventions and studies were categorized into development, feasibility and/piloting, evaluation, or implementation phase based on the UK Medical Research Council (MRC) framework for developing and evaluating complex interventions. …”
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2520por Musarò, Antonio, Dobrowolny, Gabriella, Cambieri, Chiara, Onesti, Emanuela, Ceccanti, Marco, Frasca, Vittorio, Pisano, Annalinda, Cerbelli, Bruna, Lepore, Elisa, Ruffolo, Gabriele, Cifelli, Pierangelo, Roseti, Cristina, Giordano, Carla, Gori, Maria Cristina, Palma, Eleonora, Inghilleri, Maurizio“…All the patients underwent a median nerve conduction (compound muscle action potential, CMAP) study and a clinical examination that included a handgrip strength test and an evaluation of upper limb muscle strength by means of the Medical Research Council Muscle Scale (MRC). Muscle biopsy was then performed bilaterally on the flexor carpi radialis muscle to monitor morpho-functional parameters and molecular changes. …”
Publicado 2019
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