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2521por Kernebeck, Sven, Holle, Daniela, Pogscheba, Patrick, Jordan, Felix, Mertl, Fabian, Huldtgren, Alina, Bader, Sebastian, Kirste, Thomas, Teipel, Stefan, Holle, Bernhard, Halek, Margareta“…METHODS: In this feasibility study, we perform an outcome and a process evaluation with a pre-post descriptive design over an 8-week intervention period. The Medical Research Council framework guides the design of this feasibility study. …”
Publicado 2019
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2522por Juárez, Sol Pía, Honkaniemi, Helena, Dunlavy, Andrea C, Aldridge, Robert W, Barreto, Mauricio L, Katikireddi, Srinivasa Vittal, Rostila, Mikael“…FUNDING: Swedish Council for Health, Working Life, and Social Research; UK Medical Research Council; Scottish Government Chief Scientist Office.…”
Publicado 2019
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2523“…Patient-reported activity limitations were converted to the Medical Research Council (MRC) Dyspnoea Scale, New York Heart Association (NYHA) classification and metabolic equivalents (METs) in which 1 MET equals the consumption of 3.5 mL O(2) per kilogram of body weight per minute. …”
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2524por Azzopardi, Peter S, Hearps, Stephen J C, Francis, Kate L, Kennedy, Elissa C, Mokdad, Ali H, Kassebaum, Nicholas J, Lim, Stephen, Irvine, Caleb M S, Vos, Theo, Brown, Alex D, Dogra, Surabhi, Kinner, Stuart A, Kaoma, Natasha S, Naguib, Mariam, Reavley, Nicola J, Requejo, Jennifer, Santelli, John S, Sawyer, Susan M, Skirbekk, Vegard, Temmerman, Marleen, Tewhaiti-Smith, Jordan, Ward, Joseph L, Viner, Russell M, Patton, George C“…FUNDING: Australian National Health and Medical Research Council, and the Bill & Melinda Gates Foundation.…”
Publicado 2019
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2525“…METHODS: The Medical Research Council guidelines for complex interventions were used to guide the intervention’s development. …”
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2526por Kouimtsidis, Christos, Houghton, Ben, Gage, Heather, Notley, Caitlin, Maskrey, Vivienne, Clark, Allan, Holland, Richard, Lingford-Hughes, Anne, Punukollu, Bhaskar, Duka, Theodora“…METHODS: The study corresponds to phase 2 of the Medical Research Council (MRC) complex interventions guidelines which cover the development and feasibility testing of an intervention. …”
Publicado 2019
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2527por Ponatshego, Ponego Lloyd, Lawrence, David Stephen, Youssouf, Nabila, Molloy, Sile F, Alufandika, Melanie, Bango, Funeka, Boulware, David R, Chawinga, Chimwemwe, Dziwani, Eltas, Gondwe, Ebbie, Hlupeni, Admire, Hosseinipour, Mina C, Kanyama, Cecilia, Meya, David B, Mosepele, Mosepele, Muthoga, Charles, Muzoora, Conrad K, Mwandumba, Henry, Ndhlovu, Chiratidzo E, Rajasingham, Radha, Sayed, Sumaya, Shamu, Shepherd, Tsholo, Katlego, Tugume, Lillian, Williams, Darlisha, Maheswaran, Hendramoorthy, Shiri, Tinevimbo, Boyer-Chammard, Timothée, Loyse, Angela, Chen, Tao, Wang, Duolao, Lortholary, Olivier, Lalloo, David G, Meintjes, Graeme, Jaffar, Shabbar, Harrison, Thomas S, Jarvis, Joseph N, Niessen, Louis Wilhelmus“…ETHICS AND DISSEMINATION: The AMBIsome Therapy Induction OptimisatioN (AMBITION) trial has been evaluated and approved by the London School of Hygiene and Tropical Medicine, University of Botswana, Malawi National Health Sciences, University of Cape Town, Mulago Hospital and Zimbabwe Medical Research Council research ethics committees. All participants will provide written informed consent or if lacking capacity will have consent provided by a proxy. …”
Publicado 2019
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2528por Jeong, Sarah, Barrett, Tomiko, Ohr, Se Ok, Cleasby, Peter, David, Michael, Chan, Sally, Fairlamb, Helen, Davey, Ryan, Saul, Peter“…This study will operate in accordance with the National Health and Medical Research Council’s National Statement on Ethical Conduct in Human Research (2007) and the CPMP/ICH Note for Guidance on Good Clinical Practice.…”
Publicado 2019
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2529por Pullan, Rachel L, Halliday, Katherine E, Oswald, William E, Mcharo, Carlos, Beaumont, Emma, Kepha, Stella, Witek-McManus, Stefan, Gichuki, Paul M, Allen, Elizabeth, Drake, Tom, Pitt, Catherine, Matendechero, Sultani H, Gwayi-Chore, Marie-Claire, Anderson, Roy M, Njenga, Sammy M, Brooker, Simon J, Mwandawiro, Charles S“…FUNDING: Bill & Melinda Gates Foundation, the Joint Global Health Trials Scheme of the Medical Research Council, the UK Department for International Development, the Wellcome Trust, and the Children's Investment Fund Foundation.…”
Publicado 2019
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2530por Gynther, Bruce, Charlson, Fiona, Obrecht, Karin, Waller, Michael, Santomauro, Damian, Whiteford, Harvey, Hunter, Ernest“…FJC is supported by an Australian National Health and Medical Research Council (NHMRC) Early Career Fellowship (APP1138488).…”
Publicado 2019
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2531por Walter, Florian, Carr, Matthew J, Mok, Pearl L H, Antonsen, Sussie, Pedersen, Carsten B, Appleby, Louis, Fazel, Seena, Shaw, Jenny, Webb, Roger T“…Improved inter-agency liaison, intensive follow-up immediately after discharge, and longer-term social support are indicated. FUNDING: Medical Research Council, European Research Council, and Wellcome Trust.…”
Publicado 2019
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2532por Costiniuk, CT, Nitulescu, R, Saneei, Z, Wasef, N, Salahuddin, S, Wasef, D, Young, J, de Castro, C, Routy, JP, Lebouché, B, Cox, J, Smith, BM, Ambroise, S, Pexos, C, Patel, M, Szabo, J, Haraoui, LP, de Pokomandy, A, Tsoukas, C, Falutz, J, LeBlanc, R, Giannakis, A, Frenette, C, Jenabian, MA, Bourbeau, J, Klein, MB“…Airflow obstruction was defined as forced expiratory volume in 1 s (FEV (1))/forced vital capacity (FVC) < 0.7 post‐bronchodilation, whereas COPD was defined as FEV (1)/FVC < 0.7 post‐bronchodilation and Medical Research Council (MRC) score > 2. Multivariate logistic regression was used to evaluate risk factors associated with airflow obstruction, reported as adjusted odds ratios (aORs). …”
Publicado 2019
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2533por Liang, Lirong, Cai, Yutong, Barratt, Benjamin, Lyu, Baolei, Chan, Queenie, Hansell, Anna L, Xie, Wuxiang, Zhang, Di, Kelly, Frank J, Tong, Zhaohui“…FUNDING: UK Medical Research Council.…”
Publicado 2019
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2534por Perez, Thierry, Deslée, Gaëtan, Burgel, Pierre Régis, Caillaud, Denis, Le Rouzic, Olivier, Zysman, Maeva, Escamilla, Roger, Jebrak, Gilles, Chanez, Pascal, Court-Fortune, Isabelle, Brinchault-Rabin, Graziella, Nesme-Meyer, Pascale, Paillasseur, Jean-Louis, Roche, Nicolas“…Multivariate logistic regression analyses assessed the influence on 6MWD and EID of age, sex, obesity (body mass index, BMI >30 kg/m(2)), low BMI (BMI <18.5 kg/m(2)), modified Medical Research Council (mMRC) dyspnea scale, FEV1% pred, FVC % pred, hyperinflation and comorbidities including cardiovascular diseases. …”
Publicado 2019
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2535por Saal, Susanne, Klingshirn, Hanna, Beutner, Katrin, Strobl, Ralf, Grill, Eva, Müller, Martin, Meyer, Gabriele“…A cluster-randomised pilot trial was conducted to assess the feasibility of study procedures in preparation for a main trial according to the UK Medical Research Council (MRC) framework. METHODS: Nursing homes in two regions of Germany were randomly allocated either to the intervention or optimised standard care (control group). …”
Publicado 2019
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2536por Yan, Peng, Liu, Pengfei, Lin, Rong, Xiao, Kun, Xie, Sheling, Wang, Kaifei, Zhang, Yuhan, He, Xanxue, Zhao, Shifeng, Zhang, Xingang, Liu, Martin, Xie, Lixin“…The COPD Assessment Test (CAT) score was significantly higher in Beijing (26.4±7.1) than that in Sanya (20.0±8.0, p=0.019). Modified Medical Research Council dyspnea scale was also significantly higher in Beijing (2.9±0.9) than that in Sanya (1.9±0.8, p<0.001). …”
Publicado 2019
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2537por Zuurbier, Susanna M, Hickman, Charlotte R, Tolias, Christos S, Rinkel, Leon A, Leyrer, Rebecca, Flemming, Kelly D, Bervini, David, Lanzino, Giuseppe, Wityk, Robert J, Schneble, Hans-Martin, Sure, Ulrich, Al-Shahi Salman, Rustam“…FUNDING: UK Medical Research Council, Chief Scientist Office of the Scottish Government, The Stroke Association, Cavernoma Alliance UK, and the Remmert Adriaan Laan Foundation.…”
Publicado 2019
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2538por Alter, Peter, Mayerhofer, Barbara A, Kahnert, Kathrin, Watz, Henrik, Waschki, Benjamin, Andreas, Stefan, Biertz, Frank, Bals, Robert, Vogelmeier, Claus F, Jörres, Rudolf A“…METHODS: Patients from the COPD cohort COSYCONET with data on lung function, including FEV(1), residual volume/total lung capacity (RV/TLC) ratio, diffusing capacity TLCO, and echocardiographic data on left ventricular ejection fraction (LVEF) and end-diastolic diameter (LVEDD), medical history, medication, modified British Medical Research Council dyspnea scale (mMRC) and Saint Georges Respiratory Questionnaire (SGRQ) were analyzed. …”
Publicado 2019
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2539por Grossi, Carlota M., Richardson, Kathryn, Fox, Chris, Maidment, Ian, Steel, Nicholas, Loke, Yoon K., Arthur, Antony, Myint, Phyo Kyaw, Campbell, Noll, Boustani, Malaz, Robinson, Louise, Brayne, Carol, Matthews, Fiona E., Savva, George M.“…METHODS: We used data from the baseline (Y0), 2-year (Y2) and 10-year (Y10) waves of the Medical Research Council Cognitive Function and Ageing Study. …”
Publicado 2019
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2540por Safran-Norton, Clare E., Sullivan, James K., Irrgang, James J., Kerman, Hannah M., Bennell, Kim L., Calabrese, Gary, Dechaves, Leigh, Deluca, Brian, Gil, Alexandra B., Kale, Madhuri, Luc-Harkey, Brittney, Selzer, Faith, Sople, Derek, Tonsoline, Peter, Losina, Elena, Katz, Jeffrey N.“…The process was guided in part by Medical Research Council guidance on intervention development. …”
Publicado 2019
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