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2901por Chaplin, Emma, Ward, Sarah, Daynes, Enya, Bourne, Claire LA, Stenson, Amy, Watt, Amye, Gardiner, Nikki, Houchen-Wolloff, Linzy, Singh, Sally J“…RESULTS: 272 patients (n=193 chronic respiratory disease (CRD) and n=79 CHF) were assessed and enrolled into BR (153 men, mean (SD) age 68.8 (12.7) years, body mass index 28.8 (7.3), Medical Research Council 3 (IQR 2–4), New York Heart Association 2 (IQR 2–3)). 164 patients completed the programme. …”
Publicado 2021
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2902por Oluwasanu, Mojisola Morenike, Adebayo, Ayodeji Matthew, Okunade, Faizah Tosin, Ajayi, Olayinka, Akindele, Akinwumi Oyewole, Stanback, John, Ajuwon, Ademola Johnson“…METHODS: The study utilised a mixed methods, convergent parallel design guided by the UK Medical Research Council framework. Quantitative data were obtained from 140 trained PMVs and 145 of their clients in three states and 27 in-depth interviews were conducted among relevant stakeholders. …”
Publicado 2021
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2903por Deng, Ning, Sheng, Leiyi, Jiang, Wangshu, Hao, Yongfa, Wei, Shuoshuo, Wang, Bei, Duan, Huilong, Chen, Juan“…METHODS: Guided by the medical research council (MRC) framework the process of this study was divided into four steps. …”
Publicado 2021
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2904por Riddell, Michaela A., Mini, G. K., Joshi, Rohina, Thrift, Amanda G., Guggilla, Rama K., Evans, Roger G., Thankappan, Kavumpurathu R., Chalmers, Kate, Chow, Clara K., Mahal, Ajay S., Kalyanram, Kartik, Kartik, Kamakshi, Suresh, Oduru, Thomas, Nihal, Maulik, Pallab K., Srikanth, Velandai K., Arabshahi, Simin, Varma, Ravi P., D'Esposito, Fabrizio, Oldenburg, Brian“…Methods: Our mixed methods process evaluation was guided by the United Kingdom Medical Research Council guidelines for complex interventions. …”
Publicado 2021
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2905por Mationg, Mary Lorraine S, Williams, Gail M, Tallo, Veronica L, Olveda, Remigio M, Aung, Eindra, Alday, Portia, Reñosa, Mark Donald, Daga, Chona Mae, Landicho, Jhoys, Demonteverde, Maria Paz, Santos, Eunice Diane, Bravo, Thea Andrea, Bieri, Franziska Angly, Bedford, Andrew, Li, Yuesheng, Clements, Archie C A, Steinmann, Peter, Halton, Kate, Stewart, Donald E, McManus, Donald P, Gray, Darren J“…FUNDING: National Health and Medical Research Council, Australia, and the UBS-Optimus Foundation, Switzerland.…”
Publicado 2021
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2906por Wong, Siobhan, Hassett, Leanne, Koorts, Harriet, Grunseit, Anne, Tong, Allison, Tiedemann, Anne, Greaves, Colin J., Haynes, Abby, Milat, Andrew, Harvey, Lisa A., Taylor, Nicholas F., Hinman, Rana S., Pinherio, Marina De Barros, Jennings, Matthew, Treacy, Daniel, O’Rourke, Sandra, West, Courtney, Ramsay, Elizabeth, Kirkham, Catherine, Morris, Claire, Sherrington, Catherine“…METHODS: A mixed methods process evaluation protocol was developed informed by the Medical Research Council (MRC) guidance on process evaluations for complex interventions and the PRACTIS guide. …”
Publicado 2022
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2907por Healy, Katie, Pin, Elisa, Chen, Puran, Söderdahl, Gunnar, Nowak, Piotr, Mielke, Stephan, Hansson, Lotta, Bergman, Peter, Smith, C.I. Edvard, Ljungman, Per, Valentini, Davide, Blennow, Ola, Österborg, Anders, Gabarrini, Giorgio, Al-Manei, Khaled, Alkharaan, Hassan, Sobkowiak, Michał Jacek, Yousef, Jamil, Mravinacova, Sara, Cuapio, Angelica, Xu, Xinling, Akber, Mira, Loré, Karin, Hellström, Cecilia, Muschiol, Sandra, Bogdanovic, Gordana, Buggert, Marcus, Ljunggren, Hans-Gustaf, Hober, Sophia, Nilsson, Peter, Aleman, Soo, Sällberg Chen, Margaret“…FUNDING: Knut and Alice Wallenberg Foundation, Erling Perssons family foundation, Region Stockholm, Swedish Research Council, Karolinska Institutet, Swedish Blood Cancer Foundation, PID patient organization of Sweden, Nordstjernan AB, Center for Medical Innovation (CIMED), Swedish Medical Research Council, and Stockholm County Council (ALF).…”
Publicado 2022
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2908por Beksinska, Alicja, Beattie, Tara S, Platt, Lucy, Bhattacharjee, Parinita, Prakash, Ravi, Ramanaik, Satyanarayana, Dibbadahalli, Kavitha, Collumbien, Martine, Gafos, Mitzy, Davey, Calum, Watts, Charlotte, Isac, Shajy, Jewkes, Rachel“…Samvedana Plus was funded by UKaid through Department for International Development as part of STRIVE (structural drivers of HIV) led by London School of Hygiene and Tropical Medicine and the What Works to Prevent Violence Against Women and Girls Global Programme led by South African Medical Research Council…”
Publicado 2021
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2909por Blakney, Rebekah A., Ricotta, Emily E., Follmann, Dean, Drew, Jessica, Carey, Kelly A., Glass, Lisa N., Robinson, Chevalia, MacDonald, Sandra, McShane, Pamela J., Olivier, Kenneth N., Fennelly, Kevin, Prevots, D. Rebecca“…George’s Respiratory Questionnaire (SGRQ), Medical Research Council Dyspnea Scale, and the Pulmonary Symptom Severity Score (PSSS). …”
Publicado 2022
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2910por Nicol, Edward, Ramraj, Trisha, Hlongwa, Mbuzeleni, Basera, Wisdom, Jama, Ngcwalisa, Lombard, Carl, McClinton-Appollis, Tracy, Govindasamy, Darshini, Pass, Desiree, Funani, Noluntu, Aheron, Sarah, Paredes-Vincent, Ariana, Drummond, Jennifer, Cheyip, Mireille, Dladla, Sibongile, Bedford, Jason, Mathews, Cathy“…ETHICS AND DISSEMINATION: The protocol was approved by the South African Medical Research Council Health Research Ethics Committee (EC051-11/2020). …”
Publicado 2022
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2911por Clark, Joseph, Chang, Sungwon, Kinchin, Irina, Ferreira, Diana, Kochovska, Slavica, Morgan, Deidre, Poulos, Leanne M., Johnson, Miriam J., Ekström, Magnus, Currow, David C.“…Persisting breathlessness (more than three of the last six months) used the modified Medical Research Council breathlessness scale (aggregated to 0, 1, 2–4). …”
Publicado 2022
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2912por Lee, Chai Young, Shin, Sun Hye, Choi, Hye Sook, Im, Yunjoo, Kim, Bo-Guen, Song, Ju Yeun, Lee, Daegeun, Park, Hye Yun, Lim, Jun Hyeok“…Respiratory symptoms were assessed using the modified Medical Research Council (mMRC) scale and COPD assessment test (CAT) score. …”
Publicado 2022
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2913por Kivimäki, Mika, Strandberg, Timo, Pentti, Jaana, Nyberg, Solja T, Frank, Philipp, Jokela, Markus, Ervasti, Jenni, Suominen, Sakari B, Vahtera, Jussi, Sipilä, Pyry N, Lindbohm, Joni V, Ferrie, Jane E“…FUNDING: Wellcome Trust, Medical Research Council, National Institute on Aging.…”
Publicado 2022
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2914por Webber, Matthew, Falconer, Debbie, AlFarih, Mashael, Joy, George, Chan, Fiona, Davie, Clare, Hamill Howes, Lee, Wong, Andrew, Rapala, Alicja, Bhuva, Anish, Davies, Rhodri H., Morton, Christopher, Aguado-Sierra, Jazmin, Vazquez, Mariano, Tao, Xuyuan, Krausz, Gunther, Tanackovic, Slobodan, Guger, Christoph, Xue, Hui, Kellman, Peter, Pierce, Iain, Schott, Jonathan, Hardy, Rebecca, Chaturvedi, Nishi, Rudy, Yoram, Moon, James C., Lambiase, Pier D., Orini, Michele, Hughes, Alun D., Captur, Gabriella“…BACKGROUND: The life course accumulation of overt and subclinical myocardial dysfunction contributes to older age mortality, frailty, disability and loss of independence. The Medical Research Council National Survey of Health and Development (NSHD) is the world’s longest running continued surveillance birth cohort providing a unique opportunity to understand life course determinants of myocardial dysfunction as part of MyoFit46–the cardiac sub-study of the NSHD. …”
Publicado 2022
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2915por McClatchey, Kirstie, Marsh, Viv, Steed, Liz, Holmes, Steve, Taylor, Stephanie J. C., Wiener-Ogilvie, Sharon, Neal, Julia, Last, Rhian, Saxon, Ann, Pinnock, Hilary“…METHODS: Aligned with the Medical Research Council (MRC) Complex Intervention Framework, the multidisciplinary team developed educational content in three phases: (1) developmental phase, identifying educational and behaviour change theory to guide development, in consultation with a professional advisory group; (2) feasibility pilot phase, testing the education using a ‘think-aloud’ method; and (3) pre-pilot phase, delivering the education within the IMP(2)ART strategy. …”
Publicado 2022
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2916por Bountziouka, Vasiliki, Musicha, Crispin, Allara, Elias, Kaptoge, Stephen, Wang, Qingning, Angelantonio, Emanuele Di, Butterworth, Adam S, Thompson, John R, Danesh, John N, Wood, Angela M, Nelson, Christopher P, Codd, Veryan, Samani, Nilesh J“…FUNDING: UK Medical Research Council, UK Biotechnology and Biological Sciences Research Council, and British Heart Foundation.…”
Publicado 2022
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2917por Murphy, Adrianna, Šubelj, Maja, Babarczy, Balázs, Köhler, Kristina, Chapman, Evelina, Truden-Dobrin, Polonca, Oliver, Kathryn, Nahrgang, Saskia, Reinap, Marge, Kuchenmüller, Tanja“…METHODS: We used a rapid appraisal approach, combining semi-structured interviews and document review, guided by the Medical Research Council (MRC) process evaluation framework. …”
Publicado 2022
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2918por Chang, Anne B, Morgan, Lucy C, Duncan, Emma L, Chatfield, Mark D, Schultz, André, Leo, Paul J, McCallum, Gabrielle B, McInerney-Leo, Aideen M, McPhail, Steven M, Zhao, Yuejen, Kruljac, Catherine, Smith-Vaughan, Heidi C, Morris, Peter S, Marchant, Julie M, Yerkovich, Stephanie T, Cook, Anne L, Wurzel, Danielle, Versteegh, Lesley, O’Farrell, Hannah, McElrea, Margaret S, Fletcher, Sabine, D'Antoine, Heather, Stroil-Salama, Enna, Robinson, Phil J, Grimwood, Keith“…ETHICS AND DISSEMINATION: Our RCT is conducted in accordance with Good Clinical Practice and the Australian legislation and National Health and Medical Research Council guidelines for ethical conduct of Research, including that for First Nations Australians. …”
Publicado 2022
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2919por Kooner, Harkiran K, McIntosh, Marrissa J, Matheson, Alexander M, Venegas, Carmen, Radadia, Nisarg, Ho, Terence, Haider, Ehsan Ahmed, Konyer, Norman B, Santyr, Giles E, Albert, Mitchell S, Ouriadov, Alexei, Abdelrazek, Mohamed, Kirby, Miranda, Dhaliwal, Inderdeep, Nicholson, J Michael, Nair, Parameswaran, Svenningsen, Sarah, Parraga, Grace“…George’s Respiratory Questionnaire (SGRQ), modified Medical Research Council (mMRC) dyspnoea scale, modified Borg scale and International Physical Activity Questionnaire. …”
Publicado 2022
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2920“…The proportion of Th17 cells was positively correlated with COPD Assessment Test score (r = 0.266, P = 0.009), modified Medical Research Council dyspnea score (r = 0.858, P < 0.0001), and Th1 cell ratio (r = 0.403, P < 0.0001) and negatively correlated with forced vital capacity (r = − 0.367, P = 0.009) and proportion of Th2 cells (r = − 0.655, P < 0.0001). …”
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