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3261por Damanti, Sarah, Cilla, Marta, Cilona, Maria, Fici, Aldo, Merolla, Aurora, Pacioni, Giacomo, De Lorenzo, Rebecca, Martinenghi, Sabina, Vitali, Giordano, Magnaghi, Cristiano, Fumagalli, Anna, Gennaro Mazza, Mario, Benedetti, Francesco, Tresoldi, Moreno, Rovere Querini, Patrizia“…Frailty was significantly associated with: (i) confusion, as a presenting symptom of COVID-19 [odds ratio (OR) 77.84, 95% CI 4.23–1432.49, p = 0.003]; (ii) malnutrition (MNA-SF: adjusted B –5.63, 95% CI –8.39 to –2.87, p < 0.001), risk of sarcopenia (SARC-F: adjusted B 9.11, 95% CI 3.10–15.13, p = 0.003), impaired muscle performance (SPPB: B –3.47, 95% CI –6.33 to –0.61, p = 0.02), complaints in mobility (adjusted OR 1674200.27, 95% CI 4.52–619924741831.25, p = 0.03), in self-care (adjusted OR 553305.56, 95% CI 376.37–813413358.35, p < 0.001), and in performing usual activities of daily living (OR 71.57, 95% CI 2.87–1782.53, p = 0.009) at 1-month follow-up; (iii) dyspnea [modified Medical Research Council (mMRC): B 4.83, 95% CI 1.32–8.33, p = 0.007] and risk of sarcopenia (SARC-F: B 7.12, 95% CI 2.17–12.07, p = 0.005) at 3-month follow-up; and (iv) difficulties in self-care (OR 2746.89, 95% CI 6.44–1172310.83, p = 0.01) at the 6-month follow-up. …”
Publicado 2022
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3262por Battistella, Linamara Rizzo, Imamura, Marta, De Pretto, Lucas Ramos, Van Cauwenbergh, Simon K H A A, Delgado Ramos, Vinicius, Saemy Tome Uchiyama, Sabrina, Matheus, Denise, Kuhn, Flavia, Amaral de Oliveira, Ana Alice, Souza Naves, Gabriella, Rossetti Mirisola, Aline, de Quadros Ribeiro, Fernando, Tadeu Sugawara, Andre, Cantarino, Mauricio, Andrade Santos Antunes Cavalca, Rafael, Pagano, Vanessa, Valentim Marques, Melina, Mendes da Silva, Elizabeth, Pereira Gomes, Alessandra, Fregni, Felipe“…OUTCOME MEASURES: Epworth Sleepiness Scale, EuroQoL-5 Dimensions-5 Levels, Functional Assessment of Chronic Illness Therapy–Fatigue, Functional Independence Measure, Functional Oral Intake Scale, Handgrip Strength, Insomnia Severity Index, Medical Research Council (MRC) Dyspnea Scale, MRC sum score, Modified Borg Dyspnea Scale, pain Visual Analogue Scale, Post-COVID-19 Functional Status, Timed Up and Go, WHO Disability Assessment Schedule 2.0, 1-Minute Sit to Stand Test. …”
Publicado 2022
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3263por Darker, Catherine D., Burke, Emma, Castello, Stefania, O’Sullivan, Karin, O’Connell, Nicola, Vance, Joanne, Reynolds, Caitriona, Buggy, Aine, Dougall, Nadine, Loudon, Kirsty, Williams, Pauline, Dobbie, Fiona, Bauld, Linda, Hayes, Catherine B.“…METHODS: Embedded qualitative design using the UK Medical Research Council’s process evaluation framework. Semi-structured interviews with trial participants (N = 21) and CFs (N = 8). …”
Publicado 2022
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3264por Scazufca, Marcia, Nakamura, Carina A, Seward, Nadine, Moreno-Agostino, Darío, van de Ven, Pepijn, Hollingworth, William, Peters, Tim J, Araya, Ricardo“…FUNDING: São Paulo Research Foundation and Joint Global Health Trials (UK Department for International Development, Medical Research Council, and the Wellcome Trust).…”
Publicado 2022
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3265por Prete, Carlos A, Buss, Lewis F, Whittaker, Charles, Salomon, Tassila, Oikawa, Marcio K, Pereira, Rafael HM, Moura, Isabel CG, Delerino, Lucas, Barral-Netto, Manoel, Tavares, Natalia M, Franca, Rafael FO, Boaventura, Viviane S, Miyajima, Fabio, Mendrone-Junior, Alfredo, de Almeida-Neto, Cesar, Salles, Nanci A, Ferreira, Suzete C, Fladzinski, Karine A, de Souza, Luana M, Schier, Luciane K, Inoue, Patricia M, Xabregas, Lilyane A, Crispim, Myuki AE, Fraiji, Nelson, Araujo, Fernando LV, Carlos, Luciana MB, Pessoa, Veridiana, Ribeiro, Maisa A, de Souza, Rosenvaldo E, da Silva, Sônia MN, Cavalcante, Anna F, Valença, Maria IB, da Silva, Maria V, Lopes, Esther, Filho, Luiz A, Mateos, Sheila OG, Nunes, Gabrielle T, Silva-Junior, Alexander L, Busch, Michael P, Castro, Marcia C, Dye, Christopher, Ratmann, Oliver, Faria, Nuno R, Nascimento, Vítor H, Sabino, Ester C“…FUNDING: This work was supported by Itaú Unibanco ‘Todos pela Saude’ program; FAPESP (grants 18/14389-0, 2019/21585-0); Wellcome Trust and Royal Society Sir Henry Dale Fellowship 204311/Z/16/Z; the Gates Foundation (INV- 034540 and INV-034652); REDS-IV-P (grant HHSN268201100007I); the UK Medical Research Council (MR/S0195/1, MR/V038109/1); CAPES; CNPq (304714/2018-6); Fundação Faculdade de Medicina; Programa Inova Fiocruz-CE/Funcap - Edital 01/2020 Number: FIO-0167-00065.01.00/20 SPU N°06531047/2020; JBS – Fazer o bem faz bem.…”
Publicado 2022
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3266por Kassanjee, Reshma, Welte, Alex, Otwombe, Kennedy, Jaffer, Maya, Milovanovic, Minja, Hlongwane, Khuthadzo, Puren, Adrian J, Hill, Naomi, Mbowane, Venice, Dunkle, Kristin, Gray, Glenda, Abdullah, Fareed, Jewkes, Rachel, Coetzee, Jenny“…FUNDING: South African Medical Research Council, South African National Treasury, Global Fund, South African Department of Science and Innovation, Wellcome Trust.…”
Publicado 2022
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3267por Ranasinghe, Lasith, Achar, Jay, Gröschel, Matthias I, Whittaker, Elizabeth, Dodd, Peter J, Seddon, James A“…As countries rebuild health systems following the COVID-19 pandemic, it is crucial that childhood tuberculosis services are placed centrally within national strategic plans. FUNDING: Medical Research Council.…”
Publicado 2022
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3268por Knudsen, Signe de Place, Roland, Caroline Borup, Alomairah, Saud Abdulaziz, Jessen, Anne Dsane, Molsted, Stig, Clausen, Tine D., Løkkegaard, Ellen, Stallknecht, Bente, Bønnelycke, Julie, Bendix, Jane M., Maindal, Helle Terkildsen“…METHODS: A mixed methods process evaluation was conducted using the UK Medical Research Council’s process evaluation framework by assessing implementation (reach, fidelity, and dose) and mechanisms of impact of the two interventions provided to pregnant women in FitMum. …”
Publicado 2022
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3269por Jose, K. A., Sharman, M. J., Stanesby, O., Greaves, S., Venn, A. J., Blizzard, L., Palmer, A., Cooper, K., Williams, J., Cleland, V. J.“…METHODS: The Medical Research Council UK’s framework for complex public health interventions guided the process evaluation. …”
Publicado 2022
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3270por Zang, Chengwu, Xian, Hang, Zhang, Hang, Che, Min, Chen, Yongxiang, Zhang, Fanliang, Cong, Rui“…Scar assessment was carried out using Scar Cosmesis Assessment and Rating Scale (SCAR scale) at the last follow-up postoperation, and the recovery of wound sensation was assessed at the same time using British Medical Research Council (BMRC) grading of sensorimotor recovery. …”
Publicado 2023
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3271por Taran, Shaurya, Coiffard, Benjamin, Huszti, Ella, Li, Qixuan, Chu, Leslie, Thomas, Claire, Burns, Stacey, Robles, Priscila, Herridge, Margaret S., Goligher, Ewan C.“…MAIN OUTCOMES AND MEASURES: Functional outcomes at 3, 6, and 12 months were evaluated with the Functional Independence Measure (FIM), the 6-Minute Walk Test (6MWT), the Medical Research Council (MRC) Scale for Muscle Strength, and the 36-Item Short Form Health Survey physical component summary (SF-36 PCS). …”
Publicado 2023
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3272por Redpath, Paula, Searle, Amelia, Wall, Cindy, Venning, Anthony, Oswald, Tassia, Glover, Fiona, Herriot, Peter“…Thus, under the National Health and Medical Research Council (NHMRC) Ethical Considerations in Quality Assurance and Evaluation Activities guidelines (NHMRC, 2014), and verified by the Southern Adelaide Local Health Network (SALHN) Research Committee (our institutional review board) via email (dated 10/09/2020), ethical review and approval were not required for this project as it constituted a quality improvement activity – specifically, a service delivery evaluation. …”
Publicado 2023
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3273por Rozenberg, Dmitry, Al Kaabi, Noor, Camacho Perez, Encarna, Nourouzpour, Sahar, Lopez-Hernandez, Laura, McGillis, Laura, Goligher, Ewan, Reid, W Darlene, Chow, Chung-Wai, Ryan, Clodagh M, Kumbhare, Dinesh, Huszti, Ella, Champagne, Kateri, Raj, Satish, Mak, Susanna, Santa Mina, Daniel, Clarke, Hance, Mittal, Nimish“…Secondary outcomes will include the evaluation of dyspnea using Medical Research Council Scale and 18-point qualitative dyspnea descriptors; diaphragmatic thickening fraction using ultrasound; respiratory muscle endurance; pulmonary function; prefrontal cortical activity using functional near-infrared spectroscopy; aerobic capacity during cardiopulmonary exercise testing; quality of life using Short Form-36; and scores from the Depression, Anxiety, and Stress scale-21. …”
Publicado 2023
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3274por Derqui, Nieves, Koycheva, Aleksandra, Zhou, Jie, Pillay, Timesh D, Crone, Michael A, Hakki, Seran, Fenn, Joe, Kundu, Rhia, Varro, Robert, Conibear, Emily, Madon, Kieran J, Barnett, Jack L, Houston, Hamish, Singanayagam, Anika, Narean, Janakan S, Tolosa-Wright, Mica R, Mosscrop, Lucy, Rosadas, Carolina, Watber, Patricia, Anderson, Charlotte, Parker, Eleanor, Freemont, Paul S, Ferguson, Neil M, Zambon, Maria, McClure, Myra O, Tedder, Richard, Barclay, Wendy S, Dunning, Jake, Taylor, Graham P, Lalvani, Ajit“…FUNDING: National Institute for Health Research Health Protection Research Unit in Respiratory Infections, Medical Research Council.…”
Publicado 2023
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3275Publicado 2023“…FUNDING: UK Research and Innovation (Medical Research Council), National Institute of Health and Care Research, and Wellcome Trust.…”
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3276por Boo, Yebeen Ysabelle, Gwacham-Anisiobi, Uchenna, Thakrar, Dixa B., Roberts, Nia, Kurinczuk, Jennifer J., Lakhanpaul, Monica, Nair, Manisha“…FUNDING: 10.13039/100010348Kellogg College, University of Oxford, 10.13039/501100014748Clarendon Fund, University of Oxford, Nuffield Department of Population Health, 10.13039/501100000769University of Oxford and 10.13039/501100000265Medical Research Council (MRC).…”
Publicado 2023
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3277por Zaidi, H, Hammersley, D, Jones, R, Hatipoglu, S, Androulakis, E, Balaban, G, Mach, L, Lota, A, Tayal, U, Khalique, Z, Guha, K, Lamata, P, Halliday, B, Prasad, S, Bishop, M“…M.J.B. is supported by a Medical Research Council New Investigator Grant (MR/N011007/1) and British Heart Foundation (Project grant PG/18/74/34077). …”
Publicado 2023
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3278por Alesi, Simon, Forslund, Maria, Melin, Johanna, Romualdi, Daniela, Peña, Alexia, Tay, Chau Thien, Witchel, Selma Feldman, Teede, Helena, Mousa, Aya“…FUNDING: 10.13039/501100000925National Health and Medical Research Council (NHMRC) of Australia Monash University.…”
Publicado 2023
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3279por Cheetham, Nathan J., Penfold, Rose, Giunchiglia, Valentina, Bowyer, Vicky, Sudre, Carole H., Canas, Liane S., Deng, Jie, Murray, Benjamin, Kerfoot, Eric, Antonelli, Michela, Rjoob, Khaled, Molteni, Erika, Österdahl, Marc F., Harvey, Nicholas R., Trender, William R., Malim, Michael H., Doores, Katie J., Hellyer, Peter J., Modat, Marc, Hammers, Alexander, Ourselin, Sebastien, Duncan, Emma L., Hampshire, Adam, Steves, Claire J.“…FUNDING: 10.13039/100011721Chronic Disease Research Foundation, 10.13039/100010269Wellcome Trust, 10.13039/501100000272National Institute for Health and Care Research, 10.13039/501100000265Medical Research Council, 10.13039/501100000274British Heart Foundation, 10.13039/501100000320Alzheimer's Society, European Union, COVID-19 Driver Relief Fund, French National Research Agency.…”
Publicado 2023
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3280por McCrae, Christina S, Curtis, Ashley F, Stearns, Melanie A, Nair, Neetu, Golzy, Mojgan, Shenker, Joel I, Beversdorf, David Q, Cottle, Amelia, Rowe, Meredeth A“…METHODS: We followed Medical Research Council recommendations for evaluating complex medical interventions to explore user needs and adapt and validate content using a stepwise approach: (1) a rural dementia caregiver (n=5) and primary care provider (n=5) advisory panel gave feedback that was used to adapt NiteCAPP; (2) caregiver (n=5) and primary care provider (n=7) focus groups reviewed the newly adapted NiteCAPP CARES and provided feedback that guided further adaptations; and (3) NiteCAPP CARES was pilot-tested in caregivers (n=5) for feasibility and to establish preliminary effects. …”
Publicado 2023
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