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481“…METHODS: The Medical Research Council Cognitive Function and Ageing Study (MRC CFAS) is a multi-centre population based longitudinal study of 13,004 individuals in England and Wales. …”
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482“…INTRODUCTION: Spinal tuberculosis represents a challenging disease to treat, not because of the technical expertise or the time required to cure it, but more so because of the decisions involved to treat it. The Medical Research Council (MRC) Working Party on Tuberculosis of the Spine designed trials to help address several questions. …”
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483por Moore, Edward“…In 2012, the Bateson Review of research using non-human primates (NHPs) recommended the commissioning of a working group to identify and follow-up the results of UK-funded NHP research of potential benefit for human health (Recommendation 4), but the Medical Research Council (MRC) has postponed implementation of the recommendation. …”
Publicado 2014
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484por Fitchett, Joseph R., Head, Michael G., Cooke, Mary K., Wurie, Fatima B., Atun, Rifat“…The Wellcome Trust was the leading investor with £688 million (26.5%), closely followed by the UK Medical Research Council (MRC) with £673 million (25.9%). Funding over time was volatile, ranging from ∼£40 million to ∼£160 million per year for philanthropic organisations and ∼£30 million to ∼£230 million for public funders. …”
Publicado 2014
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485por Camcıoğlu, Burcu, Boşnak-Güçlü, Meral, Karadallı, Müşerrefe Nur, Akı, Şahika Zeynep, Türköz-Sucak, Gülsan“…Functional exercise capacity was evaluated using six-minute walk test, respiratory muscle strength using mouth pressure device, hand grip strength using hand-held dynamometer, pain using Visual Analogue Scale, fatigue using Fatigue Severity Scale, dyspnea using Modified Medical Research Council Scale, and health related quality of life using European Organization for Research and Treatment of Cancer QOL measurement. …”
Publicado 2015
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486por Divan, Gauri, Hamdani, Syed Usman, Vajartkar, Vivek, Minhas, Ayesha, Taylor, Carol, Aldred, Catherine, Leadbitter, Kathy, Rahman, Atif, Green, Jonathan, Patel, Vikram“…DESIGN: The adaptation process used the Medical Research Council framework for the development and adaptation of complex interventions, focusing on qualitative methods and case series and was conducted simultaneously in India and Pakistan. …”
Publicado 2015
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487por Boyd, Kevin D, Ross, Fiona M, Chiecchio, Laura, Dagrada, GianPaolo, Konn, Zoe J, Tapper, William J, Walker, Brian A, Wardell, Christopher P, Gregory, Walter M, Szubert, Alex J, Bell, Sue E, Child, J Anthony, Jackson, Graham H, Davies, Faith E, Morgan, Gareth J“…The association of genetic lesions detected by FISH with survival was analyzed in 1069 patients with newly presenting myeloma treated in the Medical Research Council (MRC) Myeloma IX trial, with the aim of identifying patients associated with the worst prognosis. …”
Publicado 2011
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488por Pastorino, Silvia, Richards, Marcus, Hardy, Rebecca, Abington, Jane, Wills, Andrew, Kuh, Diana, Pierce, Mary“…Using data from the Medical Research Council National Survey of Health and Development (NSHD), self-reported diabetes was determined either in response to a direct question at five follow-ups between 1977 and 2010, or from other self-reported medical information. …”
Publicado 2015
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489por Bradley, B. D., Light, J. D., Ebonyi, A. O., N'Jai, P. C., Ideh, R. C., Ebruke, B. E., Nyassi, E., Peel, D., Howie, S. R. C.“…SETTING: A 42-bed hospital operated by the Medical Research Council (MRC) Unit in The Gambia. OBJECTIVE: To devise, test and evaluate a cost-efficient uninterrupted oxygen system in the MRC Hospital. …”
Publicado 2016
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490por Ban, Wooho, Lee, Jong Min, Ha, Jick Hwan, Yeo, Chang Dong, Kang, Hyeon Hui, Rhee, Chin Kook, Moon, Hwa Sik, Lee, Sang Haak“…We enrolled patients with NSCLC and evaluated symptoms of dyspnea using modified Medical Research Council (mMRC) scores. Also, we estimated pulmonary functions and analyzed survival data. …”
Publicado 2016
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491“…Key components of the UK Medical Research Council’s framework for the design and evaluation of complex interventions are discussed in relation to using taxonomies of behavior change. …”
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492por Tombor, Ildiko, Shahab, Lion, Brown, Jamie, Crane, David, Michie, Susan, West, Robert“…The development of a smartphone app (‘SmokeFree Baby’) to help pregnant women stop smoking was guided by frameworks for developing complex interventions, including the Medical Research Council (MRC), Multiphase Optimization Strategy (MOST) and Behaviour Change Wheel (BCW). …”
Publicado 2016
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493por Soothill, Germander, Darboe, Saffiatou, Bah, Gibril, Bolarinde, Lawal, Cunnington, Aubrey, Anderson, Suzanne T.“…We conducted a retrospective analysis of SCA patients admitted to the Medical Research Council Unit, The Gambia, during a 5-year period when there was high coverage of Hib and Pneumococcal conjugate vaccination. …”
Publicado 2016
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494por Mason, Alexina J., Gonzalez‐Maffe, Juan, Quinn, Killian, Doyle, Nicki, Legg, Ken, Norsworthy, Peter, Trevelion, Roy, Winston, Alan, Ashby, Deborah“…A phase I study to assess the safety, pharmacokinetic profile and antiretroviral efficacy of C34‐PEG(4)‐Chol, a novel peptide fusion inhibitor for the treatment of HIV infection, has been set up with Medical Research Council funding. During the study workup, Bayesian adaptive designs based on the continual reassessment method were compared with a more standard rule‐based design, with the aim of choosing a design that would maximise the scientific information gained from the study. …”
Publicado 2016
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495“…He presented with severe spasticity of both lower extremities, motor weakness with a Medical Research Council grade of 3, and sensory impairments below thoracic level 11 that included an inability to sense light touch and defects in proprioception. …”
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496“…His ankle dorsiflexors, big-toe extensors, and ankle plantar flexors on both sides were checked and categorized as motor-power Medical Research Council grade 0. His bilateral ankle-jerk reflection was absent. …”
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497“…[Results] The subjects were 14 patients (mean age 73.6 ± 6.3 years) classed based on the modified Medical Research Council dyspnea scale as 0 for 2 patients, 1 for 6 patients, and 2 for 6 patients, indicating that the patients were comparatively mild cases. …”
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498por Dimitrova, Antoaneta, Izov, Nikolay, Maznev, Ivan, Vasileva, Dance, Nikolova, Milena“…At entry and after PT, six minutes walking test (6 MWT), Borg scale and modified Medical Research Council (mMRC) scale were assessed. RESULTS: Significant changes in 6 MWT (p < 0.001) and mMRC scale (p < 0.001) were found after applied physical therapy program in patients of group A. …”
Publicado 2017
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499por Ramakrishnan, Subasree, Mustare, Veerendrakumar, Philip, Mariamma, Thennarasu, K., Periyavan, Sunder“…Other three patients with worsening of limb weakness (medical research council sum score of >5) and disability (Hughes disability grade by ≥1) fulfilled Kleyweg's criteria for TRF. …”
Publicado 2017
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500por Rajala, Kaisa, Lehto, Juho T., Sutinen, Eva, Kautiainen, Hannu, Myllärniemi, Marjukka, Saarto, Tiina“…Our secondary aim was to create a simple identification method for patients with increased need for palliative care by studying the relationship between modified Medical Research Council (mMRC) dyspnoea scale, HRQoL and symptoms. …”
Publicado 2017
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