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1261por Khalaf, Roaya, Martin, Sarah, Ellis, Cathy, Burman, Rachel, Sreedharan, Jemeen, Shaw, Christopher, Leigh, P Nigel, Turner, Martin R, Al-Chalabi, Ammar“…METHODS: Using the South-East England Register for Amyotrophic Lateral Sclerosis, we performed a retrospective longitudinal cohort study and extracted the modified Medical Research Council (MRC) muscle strength score for biceps and triceps in patients with a diagnosis of upper limb-onset ALS in the 19-year period 1996–2015. …”
Publicado 2019
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1262por Léger, Jean‐Marc, Alfa Cissé, Ousmane, Cocito, Dario, Grouin, Jean‐Marie, Katifi, Haider, Nobile‐Orazio, Eduardo, Ouaja, Rabye, Pouget, Jean, Rajabally, Yusuf A., Sevilla, Teresa, Merkies, Ingemar S. J.“…The primary endpoint was the difference between IqYmune® and Kiovig® in mean assessments of modified Medical Research Council (MMRC) 10 sum score (strength of 5 upper‐limb and 5 lower‐limb muscle groups, on both sides, giving a score from 0 to 100) during the evaluation period (non‐inferiority margin of Δ = 2). …”
Publicado 2018
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1263por Pan, Rui-Li, Swigris, Jeffrey J., Zhao, Yan-Wei, Guo, Ai-Min, Wu, Qing, Li, Si-Jia“…George's respiratory questionnaire (SGRQ), and The Medical Research Council dyspnoea scale at the baseline, and 15 patients completed cATAQ-IPF at the follow-up period 2 weeks later. …”
Publicado 2018
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1264por Charidemou, Evelina, Ashmore, Tom, Li, Xuefei, McNally, Ben D., West, James A., Liggi, Sonia, Harvey, Matthew, Orford, Elise, Griffin, Julian L.“…FUNDING: The research was supported by UK Medical Research Council grants MR/P011705/1, MC_UP_A090_1006 and MR/P01836X/1. …”
Publicado 2019
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1265por Aripaka, Karthik, Gudey, Shyam Kumar, Zang, Guangxiang, Schmidt, Alexej, Åhrling, Samaneh Shabani, Österman, Lennart, Bergh, Anders, von Hofsten, Jonas, Landström, Marene“…FUND: KAW 2012.0090, CAN 2017/544, Swedish Medical Research Council (2016-02513), Prostatacancerförbundet, Konung Gustaf V:s Frimurarestiftelse and Cancerforskningsfonden Norrland. …”
Publicado 2019
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1266“…Patients completed a pulmonary function test, six-minute walk test (6-MWT), COPD assessment test (CAT), and modified Medical Research Council (mMRC) dyspnea scale. Comparisons were then made according to their smoking status. …”
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1267por Saarijärvi, Markus, Wallin, Lars, Moons, Philip, Gyllensten, Hanna, Bratt, Ewa-Lena“…METHODS AND DESIGN: Medical Research Council guidance for process evaluation of complex interventions will be the guiding framework for this mixed-method study. …”
Publicado 2019
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1268por Kato, Motoyasu, Sasaki, Shinichi, Nakamura, Takahiro, Kurokawa, Kana, Yamada, Tomoko, Ochi, Yusuke, Ihara, Hiroaki, Takahashi, Fumiyuki, Takahashi, Kazuhisa“…Performance status (PS) as a patient’s general condition, body mass index (BMI), modified Medical Research Council Dyspnea Scale score, severity of IPF at nintedanib initiation, and gastrointestinal toxicity of nintedanib were evaluated. …”
Publicado 2019
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1269por Bosco, Alessandro, Paulauskaite, Laura, Hall, Ian, Crabtree, Jason, Soni, Sujata, Biswas, Asit, Cooper, Vivien, Poppe, Michaela, King, Michael, Strydom, Andre, Crawford, Michael J., Hassiotis, Angela“…METHOD: The Medical Research Council guidance for process evaluation of complex interventions was followed. …”
Publicado 2019
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1270“…FUNDING: UK Medical Research Council and UK National Institute for Health Research.…”
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1272por Xie, Chenli, Wen, Yongtao, Zhao, Yiju, Zeng, Sufen, Guo, Qingling, Liang, Qiuting, Chen, Lichong, Liu, Yuanbin, Qiu, Fuman, Yang, Lei, Lu, Jiachun“…Likewise, patients with bronchiectasis with comorbid COPD had worse lung function, worse COPD assessment test scores, and worse Modified Medical Research Council scores. Moreover, compared with COPD only cases, patients with bronchiectasis with comorbid COPD had higher levels of white blood cells (WBC), neutrophils, C-reactive protein (CRP), and procalcitonin (PCT) (all P<0.05). …”
Publicado 2019
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1273por Allum, W. H., Smyth, E. C., Blazeby, J. M., Grabsch, H. I., Griffin, S. M., Rowley, S., Cafferty, F. H., Langley, R. E., Cunningham, D.“…BACKGROUND: The UK Medical Research Council ST03 trial compared perioperative epirubicin, cisplatin and capecitabine (ECX) chemotherapy with or without bevacizumab (B) in gastric and oesophagogastric junctional cancer. …”
Publicado 2019
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1274por Komarzynski, Sandra, Bolborea, Matei, Huang, Qi, Finkenstädt, Bärbel, Lévi, Francis“…This model helps integrate circadian clocks into precision medicine and will enable treatment timing personalization following further validation. FUNDING: Medical Research Council, United Kingdom; AP-HP Foundation; and INSERM.…”
Publicado 2019
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1275“…George’s Respiratory Questionnaire (SGRQ), and modified Medical Research Council (mMRC) scale and MCFS, respectively. …”
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1276por Marel, Christina, Mills, Katherine L., Slade, Tim, Darke, Shane, Ross, Joanne, Teesson, Maree“…FUNDING: Australian National Health and Medical Research Council.…”
Publicado 2019
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1277“…TtD was defined as the time from randomisation to the first deterioration in the EORTC QLQ-C15, PAL EORTC QLQ-BN20 and Medical Research Council (MRC)-Neurological status. Deterioration was defined as a decrease of ≥ 10 points from baseline in the QLQ-C15 PAL overall QoL and functioning scales, an increase of ≥ 10 points from baseline in the QLQ-C15 PAL fatigue scale and the QLQ-BN20 total sum of score, and a rating of “Worse” in the MRC-Neurological status. …”
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1278por Richards, David A, Bazeley, Patricia, Borglin, Gunilla, Craig, Peter, Emsley, Richard, Frost, Julia, Hill, Jacqueline, Horwood, Jeremy, Hutchings, Hayley Anne, Jinks, Clare, Montgomery, Alan, Moore, Graham, Plano Clark, Vicki L, Tonkin-Crine, Sarah, Wade, Julia, Warren, Fiona C, Wyke, Sally, Young, Bridget, O'Cathain, Alicia“…This paper reports on a 2 day expert meeting funded by the United Kingdom Medical Research Council Hubs for Trials Methodology Research with the aims to identify current strengths and weaknesses in the integration of quantitative and qualitative methods in clinical trials, establish the next steps required to provide the trials community with guidance on the integration of mixed methods in RCTs and set-up a network of individuals, groups and organisations willing to collaborate on related methodological activity. …”
Publicado 2019
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1279“…Specifically, the 2009 Australian National Health and Medical Research Council drinking guidelines recommend that adults should not drink more than two standard drinks on any day on average, and no more than four drinks on a single occasion. …”
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1280por Narendran, Parth, Quann, Niamh, Nagi, Dinesh, Gallen, Ian, Gorton, Janet, Daly, Heather, Thompson, Catherine, Bhupendra Jaicim, Nishal, Davies, Melanie, Andrews, Robert C“…The first stage develops an education program aimed to support people with T1DM to exercise using the Medical Research Council framework. The second stage is a pilot randomized controlled trial (RCT) that aims to collect the key variables to design a definitive trial to test the efficacy and cost-effectiveness of the education package. …”
Publicado 2019
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