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1601por Macdonald-Wallis, Corrie, Silverwood, Richard J, de Stavola, Bianca L, Inskip, Hazel, Cooper, Cyrus, Godfrey, Keith M, Crozier, Sarah, Fraser, Abigail, Nelson, Scott M, Lawlor, Debbie A, Tilling, Kate“…Funding, competing interests, data sharing UK Wellcome Trust, US National Institutes of Health, and UK Medical Research Council. Other funding sources for authors are detailed in the full online paper. …”
Publicado 2015
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1602“…Among patients with a Medical Research Council dyspnea score recorded during 24 months follow-up, a substantial proportion of adherent patients (LAMA: 41 %; LABA: 45 %; LABA+ICS 44 %) had clinically significant dyspnoea (MRC ≥ 3). …”
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1603por Navani, Neal, Nankivell, Matthew, Lawrence, David R, Lock, Sara, Makker, Himender, Baldwin, David R, Stephens, Richard J, Parmar, Mahesh K, Spiro, Stephen G, Morris, Stephen, Janes, Sam M“…FUNDING: UK Medical Research Council.…”
Publicado 2015
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1604“…METHODS: The Medical Research Council’s (MRC) framework for developing and evaluating complex interventions was adopted to develop an intervention for couples coping with cancer. …”
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1605por Tudur Smith, C., Hopkins, C., Sydes, M. R., Woolfall, K., Clarke, M., Murray, G., Williamson, P.“…BACKGROUND: Individual participant data (IPD) from completed clinical trials should be responsibly shared to support efficient clinical research, generate new knowledge and bring benefit to patients. The Medical Research Council (MRC) Hubs for Trials Methodology Research (HTMR) has developed guidance to facilitate the sharing of IPD from publicly funded clinical trials. …”
Publicado 2015
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1606“…Values and Ethics: Guidelines for Ethical conduct in Aboriginal and Torres Strait Islander Health Research (hereafter referred to as Values and Ethics), developed by The National Health and Medical Research Council of Australia in 2003, is the ethical standard for Indigenous-focused health research. …”
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1607“…METHODS: We tested the associations between teacher-rated self-control at ages 13 and 15 years, and measured body mass index (BMI) between ages 15 and 60–64 years, controlling for confounding factors such as affective symptoms and cognition, using 3873 study members in the Medical Research Council National Survey of Health and Development, also known as the British 1946 birth cohort. …”
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1608“…Presence of respiratory symptoms was determined from self-report of chronic productive cough and breathlessness assessed using the British Medical Research Council (MRC) breathlessness scale. Self-reported physical and mental health were measured using the 12-Item Short-Form Health Survey (SF-12). …”
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1609por McCalman, Janya, Bainbridge, Roxanne, Russo, Sandra, Rutherford, Katrina, Tsey, Komla, Wenitong, Mark, Shakeshaft, Anthony, Doran, Chris, Jacups, Susan“…The 5-year project was funded by the Australian National Health and Medical Research Council from December 2014. METHODS/DESIGN: An integrated mixed methods approach will be adopted; each component iteratively informing the other. …”
Publicado 2016
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1610por Vorrink, Sigrid NW, Kort, Helianthe SM, Troosters, Thierry, Lammers, Jan-Willem J“…METHODS: The design process consisted of literature research and the iterative developing and piloting phases of the Medical Research Council (MRC) model for complex clinical interventions and the involvement of end users. …”
Publicado 2016
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1611por Wu, Xiujuan, Shen, Donghui, Li, Ting, Zhang, Bing, Li, Chunrong, Mao, Mei, Zhao, Jixue, Liu, Kangding, Zhang, Hong-Liang“…Similar to adults, bulbar dysfunction (odds ratio [OR]: 4.621, 95% confidence interval [CI]: 1.240–17.218, p < 0.05) and lower nadir Medical Research Council (MRC) sum score (OR: 0.897, 95% CI: 0.855–0.941, p < 0.01) were also risk factors for mechanical ventilation in children. …”
Publicado 2016
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1612por Pearson, Jennifer, Richardson, Jane, Calnan, Michael, Salisbury, Chris, Foster, Nadine E.“…BACKGROUND: In response to long waiting lists and problems with access to primary care physiotherapy, several Primary Care Trusts (PCTs) (now Clinical Commissioning Groups CCGs) developed physiotherapy-led telephone assessment and treatment services. The Medical Research Council (MRC) funded PhysioDirect trial was a randomised control trial (RCT) in four PCTs, with a total of 2252 patients that compared this approach with usual physiotherapy care. …”
Publicado 2016
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1613“…PARTICIPANTS: Up to 2093 men and women from the Medical Research Council National Survey of Health and Development, who have been followed-up since birth in 1946, and underwent physical capability assessments performed by nurses following standard protocols in 1999 and 2006–2010. …”
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1614por Greenwood-Lee, James, Hawe, Penelope, Nettel-Aguirre, Alberto, Shiell, Alan, Marshall, Deborah A.“…Complexity highlights the challenge in developing interventions as effective health solutions. The UK Medical Research Council provides guidelines on the development and evaluation of complex interventions. …”
Publicado 2016
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1615por Nielson, Carrie M., Jones, Kerry S., Chun, Rene F., Jacobs, Jon M., Wang, Ying, Hewison, Martin, Adams, John S., Swanson, Christine M., Lee, Christine G., Vanderschueren, Dirk, Pauwels, Steven, Prentice, Ann, Smith, Richard D., Shi, Tujin, Gao, Yuqian, Schepmoes, Athena A., Zmuda, Joseph M., Lapidus, Jodi, Cauley, Jane A., Bouillon, Roger, Schoenmakers, Inez, Orwoll, Eric S.“…PARTICIPANTS: Men in Osteoporotic Fractures in Men and Medical Research Council studies (N = 1057) were included. …”
Publicado 2016
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1616por Madan, Jason, Ades, Tony, Barton, Pelham, Bojke, Laura, Choy, Ernest, Helliwell, Philip, Jobanputra, Paresh, Stein, Ken, Stevens, Andrew, Tosh, Jonathan, Verstappen, Suzanne, Wailoo, Allan“…FUNDING: Arthritis Research UK and the UK Medical Research Council Network of Hubs for Trials Methodology Research. …”
Publicado 2015
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1617“…METHODS: A total of 1561 men and women were drawn from the Medical Research Council National Survey of Health and Development (the British 1946 birth cohort). …”
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1618“…The muscle strength and patients’ functional status were assessed according to the Medical Research Council (MRC) and by ALS functional rating scale revised (ALSFRS-R), respectively. …”
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1619por Khalifa, N, Talbot, E, Schneider, J, Walker, D M, Bates, P, Bird, Y, Davies, D, Brookes, C, Hall, J, Völlm, B“…In accordance with the UK Medical Research Council guidelines on the evaluation of complex interventions, a process evaluation will be carried out; qualitative interviews with patients and staff will explore general views of IPS as well as barriers and facilitators to implementation. …”
Publicado 2016
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1620“…Secondary outcomes will include 6 min walking distance, pulmonary function, the modified Medical Research Council Dyspnoea Scale, the COPD Assessment Test, the Hospital Anxiety and Depression Scale, the Berg Balance Scale, exacerbation frequency during the study period, and systemic inflammatory and immune markers. …”
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