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1661por Kim, Woo Jin, Yim, Jae-Joon, Kim, Deog Kyeom, Lee, Myung Goo, Fuhlbrigge, Anne L, Sliwinski, Pawel, Hawrylkiewicz, Iwona, Wan, Emily S, Cho, Michael H, Silverman, Edwin K“…COPD subjects from Poland had more severe dyspnea (modified Medical Research Council 3.3±1.0) and more frequently reported symptoms of chronic bronchitis (52.2%). …”
Publicado 2017
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1662por Ramanathan, Shanthi, Reeves, Penny, Deeming, Simon, Bailie, Ross Stewart, Bailie, Jodie, Bainbridge, Roxanne, Cunningham, Frances, Doran, Christopher, McPhail Bell, Karen, Searles, Andrew“…ETHICS AND DISSEMINATION: This study is funded by a nationally competitive grant (ID 1078927) from the Australian National Health and Medical Research Council. Ethics approval was obtained from the University of Newcastle’s Human Research Ethics Committee (ID: H-2017–0026). …”
Publicado 2017
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1663por Farnbach, Sara, Evans, John, Eades, Anne-Marie, Gee, Graham, Fernando, Jamie, Hammond, Belinda, Simms, Matty, DeMasi, Karrina, Hackett, Maree“…ETHICS AND DISSEMINATION: The University of Sydney Human Research Ethics Committee, Aboriginal Health and Medical Research Council of New South Wales and six state ethics committees have approved this research. …”
Publicado 2017
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1664por Currow, David, Watts, Gareth John, Johnson, Miriam, McDonald, Christine F, Miners, John O, Somogyi, Andrew A, Denehy, Linda, McCaffrey, Nicola, Eckert, Danny J, McCloud, Philip, Louw, Sandra, Lam, Lawrence, Greene, Aine, Fazekas, Belinda, Clark, Katherine C, Fong, Kwun, Agar, Meera R, Joshi, Rohit, Kilbreath, Sharon, Ferreira, Diana, Ekström, Magnus“…A recent large phase III study suggests the subgroup most likely to benefit have chronic obstructive pulmonary disease (COPD) and modified Medical Research Council breathlessness scores of 3 or 4. This protocol is for an adequately powered, parallel-arm, placebo-controlled, multisite, factorial, block-randomised study evaluating regular ER morphine for chronic breathlessness in people with COPD. …”
Publicado 2017
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1665“…The PBT consisted of multidirectional exercises executed synchronously with unaffected limb and verbal feedback. The Medical Research Council scale (MRC), Dynamometer, Fugl-Meyer Upper Extremity scale (F-M UE), Functional Independence Measure scale (FIM) and modified Ashworth scale were administered at the beginning and at the end of training. …”
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1666por Wylde, Vikki, Howells, Nicholas, Bertram, Wendy, Moore, Andrew J., Bruce, Julie, McCabe, Candy, Blom, Ashley W., Dennis, Jane, Burston, Amanda, Gooberman-Hill, Rachael“…METHODS: In line with the UK Medical Research Council’s recommendations for comprehensive development of complex interventions, multiple phases of work were undertaken. …”
Publicado 2018
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1667“…The questionnaire, based on previous designs used in similar surveys and nutrition resources developed by the National Health and Medical Research Council, was pretested prior to the survey. …”
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1668“…Overall, a substantial number of patients experienced moderate airflow limitation (~49% patients, GOLD 2 as per GOLD 2013; mean postbronchodilator forced expiratory volume in 1 second value was ~50% of the predicted value), belonged to GOLD group D (~51% patients), and had COPD assessment test score ≥10 or modified Medical Research Council score ≥2 (~79% patients), and ≤1 exacerbation in the past 1 year (~80% patients). …”
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1669“…Univariate analysis showed that more severe airflow limitation (p = 0.000), higher COPD assessment test (CAT) scores (p = 0.003) and modified Medical Research Council (mMRC) scales (p = 0.008), and the presence of at least one (p = 0.000) or two (p = 0.003) co-morbidities were significantly associated with such inconsistency. …”
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1670por Thao, Le Thi Phuong, Heemskerk, A Dorothee, Geskus, Ronald B, Mai, Nguyen Thi Hoang, Ha, Dang Thi Minh, Chau, Tran Thi Hong, Phu, Nguyen Hoan, Chau, Nguyen Van Vinh, Caws, Maxine, Lan, Nguyen Huu, Thu, Do Dang Anh, Thuong, Nguyen Thuy Thuong, Day, Jeremy, Farrar, Jeremy J, Torok, M Estee, Bang, Nguyen Duc, Thwaites, Guy E, Wolbers, Marcel“…Common predictors for increased mortality in both populations were higher Medical Research Council (MRC) disease severity grade and lower cerebrospinal fluid lymphocyte cell count. …”
Publicado 2018
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1671por Egli, Adrian, Mandal, Jyotshna, Schumann, Desiree M., Roth, Michael, Thomas, Brad, Lorne Tyrrell, D., Blasi, Francesco, Kostikas, Kostantinos, Boersma, Wim, Milenkovic, Branislava, Lacoma, Alicia, Rentsch, Katharina, Rohde, Gernot G. U., Louis, Renaud, Aerts, Joachim G., Welte, Tobias, Torres, Antoni, Tamm, Michael, Stolz, Daiana“…Compared to the TT or TG genotypes, the GG genotype was associated with severe dyspnoea (modified medical research council score ≥ median 3; 22 vs 42%, p = 0.030). …”
Publicado 2018
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1672por Dijkstra, Nienke Elske, Sino, Carolina Geertruida Maria, Heerdink, Eibert Rob, Schuurmans, Marieke Joanna“…METHODS: The development phase of the Medical Research Council (MRC) framework was followed in which an iterative human-centered design (HCD) approach was applied. …”
Publicado 2018
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1673por Al-Olabi, Lara, Polubothu, Satyamaanasa, Dowsett, Katherine, Andrews, Katrina A., Stadnik, Paulina, Joseph, Agnel P., Knox, Rachel, Pittman, Alan, Clark, Graeme, Baird, William, Bulstrode, Neil, Glover, Mary, Gordon, Kristiana, Hargrave, Darren, Huson, Susan M., Jacques, Thomas S., James, Gregory, Kondolf, Hannah, Kangesu, Loshan, Keppler-Noreuil, Kim M., Khan, Amjad, Lindhurst, Marjorie J., Lipson, Mark, Mansour, Sahar, O’Hara, Justine, Mahon, Caroline, Mosica, Anda, Moss, Celia, Murthy, Aditi, Ong, Juling, Parker, Victoria E., Rivière, Jean-Baptiste, Sapp, Julie C., Sebire, Neil J., Shah, Rahul, Sivakumar, Branavan, Thomas, Anna, Virasami, Alex, Waelchli, Regula, Zeng, Zhiqiang, Biesecker, Leslie G., Barnacle, Alex, Topf, Maya, Semple, Robert K., Patton, E. Elizabeth, Kinsler, Veronica A.“…This work was funded or supported by grants from the AVM Butterfly Charity, the Wellcome Trust (UK), the Medical Research Council (UK), the UK National Institute for Health Research, the L’Oreal-Melanoma Research Alliance, the European Research Council, and the National Human Genome Research Institute (US).…”
Publicado 2018
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1674por Cardoso, João, Coelho, Ricardo, Rocha, Carla, Coelho, Constança, Semedo, Luísa, Bugalho Almeida, A“…Forced expiratory volume in 1 s (FEV(1)), modified Medical Research Council dyspnea scale, exacerbation history (ExH), Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2011 groups, and lung volumes were reviewed. …”
Publicado 2018
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1675por Storgaard, Line Hust, Hockey, Hans-Ulrich, Laursen, Birgitte Schantz, Weinreich, Ulla Møller“…At inclusion, acute exacerbation of COPD (AECOPD) and hospital admissions 1 year before inclusion, modified Medical Research Council (mMRC) score, St George’s Respiratory Questionnaire (SGRQ), forced expiratory volume in 1 second (FEV(1)), 6-minute walk test (6MWT) and arterial carbon dioxide (PaCO(2)) were recorded. …”
Publicado 2018
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1676por Coughlan, L., Sridhar, S., Payne, R., Edmans, M., Milicic, A., Venkatraman, N., Lugonja, B., Clifton, L., Qi, C., Folegatti, P.M., Lawrie, A.M., Roberts, R., de Graaf, H., Sukhtankar, P., Faust, S.N., Lewis, D.J.M., Lambe, T., Hill, AVS, Gilbert, S.C.“…FUNDING SOURCE: Medical Research Council UK, NIHR BMRC Oxford.…”
Publicado 2018
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1677“…Most patients had dyspnea with substantial disability (modified Medical Research Council dyspnea scale rating ≥2, 56.3%; large health status impairment from symptoms, COPD Assessment Test score >20, 64.4%). …”
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1678“…Among vitamin D-deficient COPD subjects, 25(OH) D correlated positively with forced expiratory volume in 1 second as % predicted, Modified British Medical Research Council score, blood oxygenation, food portion size, Mediterranean Diet Score and Ultraviolet Score. …”
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1679por Hackett, Julia, Bekker, Hilary, Bennett, Michael I, Carder, Paul, Gallagher, Jean, Henry, Claire, Kite, Suzanne, Taylor, Sally, Velikova, Galina, Ziegler, Lucy“…METHODS AND ANALYSIS: This study is being conducted over 24 months from November 2017 to October 2019 and follows the UK Medical Research Council framework for developing complex interventions and the International Patient Decision Aids Guideline. …”
Publicado 2018
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1680por Davarzani, Nasser, Hutchins, Gordon G A, West, Nicholas P, Hewitt, Lindsay C, Nankivell, Matthew, Cunningham, David, Allum, William H, Smyth, Elizabeth, Valeri, Nicola, Langley, Ruth E, Grabsch, Heike I“…We analysed the prognostic value of TRG and associated pathological factors in OC patients enrolled in the Medical Research Council (MRC) OE02 trial. METHODS AND RESULTS: Histopathology was reviewed in 497 resections from OE02 trial participants randomised to surgery (S group; n = 244) or NAC followed by surgery [chemotherapy plus surgery (CS) group; n = 253]. …”
Publicado 2018
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