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1781“…Among them, individuals with group B symptoms were most represented (45.2%); 53.6% had Medical Research Council (MRC) dyspnea levels of 2 or above. …”
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1782por Liu, Yufei, Xie, Xiaohong, Wang, Wujun, Zhao, Keni, Xiao, Wei, Xiao, Jing, Chen, Jianqin, Zeng, Jurong, Chen, Keling“…The secondary outcomes include the declines and the between-group difference in the change from baseline to 18 months in FEV1 before bronchodilator use; the forced vital capacity (FVC), FEV1/FVC, FEV1%pred after bronchodilator use, modified British medical research council, COPD Assessment Test, St George's Respiratory Questionnaire (SGRQ); frequency, interval, duration and severity of COPD exacerbations; time to first COPD exacerbation; administration of rescue medication and a cost-effectiveness analysis; Smoking status. …”
Publicado 2020
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1783por Bowker, Nicholas, Shah, Rupal L., Sharp, Stephen J., Luan, Jian'an, Stewart, Isobel D., Wheeler, Eleanor, Ferreira, Manuel A.R., Baras, Aris, Wareham, Nicholas J., Langenberg, Claudia, Lotta, Luca A.“…FUNDING: The EPIC—Norfolk study has received funding from the Medical Research Council (MRC) (MR/N003284/1, MC-UU_12015/1 and MC_PC_13048) and Cancer Research UK (C864/A14136). …”
Publicado 2020
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1784por Seecheran, Naveen, Boodhai, Brent, Maharaj, Aarti, Ramdeen, Arvinash, Debideen, Niranjan, Ochalal, Vishesh, Singh, Randall, Seecheran, Rajeev, Seecheran, Valmiki, Persad, Sangeeta, Abdullah, Harun, Peram, Lakshmipathi, Motilal, Shastri, Tello-Montoliu, Antonio, Schneider, David“…Of the patients, 4% experienced Medical Research Council class 1 dyspnea, and Bleeding Academic Research Consortium class 1 bleeding on the ticagrelor regimen (one patient each). …”
Publicado 2020
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1785por Kitonsa, Jonathan, Ggayi, Abu-Baker, Anywaine, Zacchaeus, Kisaakye, Eva, Nsangi, Laura, Basajja, Vincent, Nyantaro, Mary, Watson-Jones, Deborah, Shukarev, Georgi, Ilsbroux, Ine, Robinson, Cynthia, Kaleebu, Pontiano“…The World Health Organisation (WHO) declared the epidemic a public health crisis that required accelerated development of novel interventions including vaccines. The Medical Research Council/Uganda Virus Research Institute and London School of Hygiene and Tropical Medicine Uganda Research Unit (MRC/UVRI & LSHTM Uganda Research Unit) was among the African research sites that implemented the VAC52150EBL1004 Ebola vaccine trial. …”
Publicado 2020
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1786por Merrick, Sophie, Nankivell, Matthew, Quartagno, Matteo, Clarke, Caroline S., Joharatnam-Hogan, Nalinie, Waddell, Tom, O'Carrigan, Brent, Seckl, Michael, Ghorani, Ehsan, Banks, Emma, Edmonds, Kim, Bray, George, Woodward, Rose, Bennett, Rachel, Badrock, Jonathan, Hudson, Will, Langley, Ruth E., Vasudev, Naveen, Pickering, Lisa, Gilbert, Duncan C.“…REFINE is funded by the Jon Moulton Charity Trust and Medical Research Council, sponsored by University College London (UCL), and coordinated by the MRC CTU at UCL. …”
Publicado 2023
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1787por Richman, Susan D, Hemmings, Gemma, Roberts, Helen, Gallop, Niall, Dodds, Rachel, Wilkinson, Lyndsay, Davis, Jonathan, White, Rhian, Yates, Emma, Jasani, Bharat, Brown, Louise, Maughan, Tim S, Butler, Rachel, Quirke, Philip, Adams, Richard“…Molecular profiling of patients’ formalin-fixed, paraffin-embedded tumour blocks was undertaken at two centralised biomarker laboratories (Leeds and Cardiff), and the results fed directly to the Medical Research Council Clinical Trials Unit, and used for subsequent randomisation. …”
Publicado 2023
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1788por Fisher, Harriet, Audrey, Suzanne, Chantler, Tracey, Finn, Adam, Letley, Louise, Mounier-Jack, Sandra, Thomas, Clare, Yates, Julie, Hickman, Matthew“…METHODS AND ANALYSIS: The Medical Research Council’s framework for development and evaluation of complex interventions will inform intervention development. …”
Publicado 2020
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1789por Peven, Kimberly, Bick, Debra, Purssell, Edward, Rotevatn, Torill Alise, Nielsen, Jane Hyldgaard, Taylor, Cath“…We recommend use of UK Medical Research Council guidelines (2015) for process evaluations and checklists for reporting implementation studies. …”
Publicado 2020
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1790por Matthews, Olivia, Morrison, Emma E., Tranter, John D., Starkey Lewis, Philip, Toor, Iqbal S., Srivastava, Abhishek, Sargeant, Rebecca, Rollison, Helen, Matchett, Kylie P., Kendall, Timothy J., Gray, Gillian A., Goldring, Chris, Park, Kevin, Denby, Laura, Dhaun, Neeraj, Bailey, Matthew A., Henderson, Neil C., Williams, Dominic, Dear, James W.“…FUNDING: Kidney Research UK, Medical Research Scotland, Medical Research Council.…”
Publicado 2020
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1791por Buttery, Sara C, Lewis, Adam, Kemp, Samuel V, Banya, Winston, Quint, Jennifer K, Steiner, Michael C, Hopkinson, Nicholas S“…PARTICIPANTS: 8295 (55.7%) of 14 889 patients in programmes using incremental shuttle walk test (ISWT) or 6-minute walk test (6MWT) as an outcome measure completed PR, and 4856 (32.6%) had complete data recorded (6MWT/ISWT, baseline spirometry, Medical Research Council (MRC) dyspnoea score). RESULTS: Depending on the walking test safety threshold adopted for the ISWT (≥140 m or ≥ 80 m) and the MRC dyspnoea score threshold used (MRC score ≥3 or ≥4 at the end of PR), between 4.9% and 18.1% of PR completers met the NICE criteria for a lung volume reduction-focused respiratory review. …”
Publicado 2020
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1792“…METHODS: The Medical Research Council framework for evaluating complex interventions and the Centre for eHealth Research roadmap served as frameworks for the stages of intervention and technology development. …”
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1793por Mazzoli, Marco, Ariatti, Alessandra, Garuti, Gian Carlo, Agnoletto, Virginia, Genovese, Maurilio, Gozzi, Manuela, Kaleci, Shaniko, Marchioni, Alessandro, Malagoli, Marcella, Galassi, Giuliana“…Neurological impairment was assessed by Muscular Impairment Rating (MIRS), Medical Research Council (MRC), and modified Rankin (mRS) scales. …”
Publicado 2020
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1794por Madden, Danielle E., Webb, Jessica R., Steinig, Eike J., Currie, Bart J., Price, Erin P., Sarovich, Derek S.“…FUNDING: National Health and Medical Research Council (BJC, EPP, DSS); Australian Government (DEM, ES); Advance Queensland (EPP, DSS).…”
Publicado 2020
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1795por Katsidzira, Leolin, Mudombi, Wisdom F, Makunike-Mutasa, Rudo, Yilmaz, Bahtiyar, Blank, Annika, Rogler, Gerhard, Macpherson, Andrew, Vavricka, Stephan, Gangaidzo, Innocent, Misselwitz, Benjamin“…ETHICS AND DISSEMINATION: Ethical approval has been obtained from the Parirenyatwa Hospital’s and University of Zimbabwe’s research ethics committee and the Medical Research Council of Zimbabwe. Findings will be discussed with patients, and the Zimbabwean Ministry of Health. …”
Publicado 2020
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1796por Kögl, Nikolaus, Brawanski, Konstantin, Girod, Pierre-Pascal, Petr, Ondra, Thomé, Claudius“…Motor function was assessed using manual muscle testing and subdivided according to the Medical Research Council (MRC) scale. Patient demographics, neurologic deficits, duration of motor deficits, treatment characteristics, and outcome were assessed. …”
Publicado 2020
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1797por Usuda, Katsuo, Iwai, Shun, Yamagata, Aika, Iijima, Yoshihito, Motono, Nozomu, Takahara, Yutaka, Shinomiya, Shohei, Oikawa, Taku, Mizuno, Shiro, Uramoto, Hidetaka“…Hospital records, the modified Medical Research Council dyspnea scale (mMRC) grade, performance status (PS), symptoms, procedure‐related complications and survival after placement were retrospectively reviewed. …”
Publicado 2020
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1798por Soma, Santosh K, Lingappa, Lokesh, Raju, Subodh, Konanki, Ramesh, Gaur, Amit K, Mohan, Ashwini, Mohanlal, Smilu“…MATERIALS AND METHODS: Diagnosis was based on the uniform research definition criteria and was staged according to the British Medical Research Council. Mantoux test, analysis of cerebrospinal fluid (CSF), CSF GeneXpert, and radiological investigations were performed. …”
Publicado 2020
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1799por Low, Joo-Leng, Lau, Dawn Pingxi, Zhang, Xiaoqian, Kwang, Xue-Lin, Rohatgi, Neha, Chan, Jane Vin, Chong, Fui-Teen, Wong, Stephen Qi Rong, Leong, Hui-Sun, Thangavelu, Matan Thangavelu, Rikka, Shivaji, Skanderup, Anders Martin Jacobsen, Tan, Daniel Shao Weng, Periyasamy, Giridharan, Koh, Judice Lie Yong, Iyer, N Gopalakrishna, DasGupta, Ramanuj“…FUNDING: Agency for Science, Technology, and Research (A*STAR), National Medical Research Council (NMRC), and the National Institutes of Health (NIH)/National Cancer Institute (NCI).…”
Publicado 2021
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1800por Kunzler, Angela M., Stoffers-Winterling, Jutta, Stoll, Marlene, Mancini, Alexander L., Lehmann, Sophie, Blessin, Manpreet, Gilan, Donya, Helmreich, Isabella, Hufert, Frank, Lieb, Klaus“…We assessed the level of evidence using a modified scheme from the Oxford Centre for Evidence-based Medicine and the Australian National Health and Medical Research Council. RESULTS: Of 4030 records found, 19 studies were included (two RCTs). …”
Publicado 2021
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