Mostrando 121 - 140 Resultados de 3,158 Para Buscar '"Merlín"', tiempo de consulta: 0.40s Limitar resultados
  1. 121
  2. 122
    por Garcia, Cynthia, Gutmann, David H.
    Publicado 2014
    “…RESULTS: We demonstrate that the Nf2 protein, merlin, negatively regulates spinal neural progenitor cell survival and glial differentiation in an ErbB2-dependent manner, and that NF2-associated spinal ependymomas exhibit increased ErbB2 activation. …”
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  3. 123
    “…Rae1 increases activation of the core kinases Hippo and Warts and plays a post-transcriptional role to increase the protein levels of the Merlin, Hippo, and Warts components of the pathway; therefore, in addition to Rae1 coordinating organ size regulation with proliferative control, we propose that Rae1 also acts in a feedback circuit to regulate pathway homeostasis.…”
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  4. 124
    “…Previous evidence showed mutations of the neurofibromin type 2 gene (Nf2), encoding the tumor suppressor protein merlin, in sporadic and vestibular schwannomas affecting Schwann cells (SCs). …”
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  5. 125
  6. 126
  7. 127
  8. 128
  9. 129
    por Wilson, Don E.
    Publicado 1997
    Libro
  10. 130
    “…Mechanistically, RICH1 activated the kinases cascade of Hippo signaling via displacing Amot-p80 from the complex with Merlin. Further studies revealed that the deletion of the BAR domain of RICH1 abolished the function of attenuating the binding of Amot-p80 and Merlin, illustrating that the competitive binding to Amot-p80 with Merlin was mediated by the BAR domain of RICH1. …”
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  11. 131
    Publicado 1999
    Libro
  12. 132
    Publicado 1970
    Libro
  13. 133
    “…CHL1 could co-localize with adhesion molecule Integrin-β1, the expression of CHL1 was positively correlated with Integrin-β1 and another known tumor suppressor gene (TSG) Merlin. Down-regulation of Integrin-β1 or Merlin was significantly correlated with the poor survival rate of NPC patients. …”
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  14. 134
  15. 135
    por Delgado Calderón, Alfredo
    Publicado 2004
    Libro
  16. 136
    por Delgado Calderón, Alfredo
    Publicado 2011
    Libro
  17. 137
    por Forster, Merlin H.
    Publicado 1964
    Libro
  18. 138
    “…Notably, PIP5Kγ90, but not its kinase-deficient mutant, potentiated Merlin–LATS1 interaction and recruited LATS1 to the PM. …”
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  19. 139
    “…TGFβ-1-induced EMT was associated with a 4-fold increase in Panc-1 cell invasiveness, which further increased ~10-fold upon knockdown of the tumor suppressor Merlin (Neurofibromatosis type 2). Knockdown of NHE1 or NBCn1 abolished Merlin-induced invasiveness, but not that induced by TGFβ-1 alone. …”
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  20. 140
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