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1221por Rajpar, M. Helen, McDermott, Ben, Kung, Louise, Eardley, Rachel, Knowles, Lynette, Heeran, Mel, Thornton, David J., Wilson, Richard, Bateman, John F., Poulsom, Richard, Arvan, Peter, Kadler, Karl E., Briggs, Michael D., Boot-Handford, Raymond P.“…Mutations in type X collagen cause metaphyseal chondrodysplasia type Schmid (MCDS), a disorder characterised by dwarfism and an expanded growth plate hypertrophic zone. …”
Publicado 2009
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1222por Cameron, Trevor L., Bell, Katrina M., Tatarczuch, Liliana, Mackie, Eleanor J., Rajpar, M. Helen, McDermott, Ben T., Boot-Handford, Raymond P., Bateman, John F.“…Metaphyseal chondrodysplasia, Schmid type (MCDS) is characterized by mild short stature and growth plate hypertrophic zone expansion, and caused by collagen X mutations. …”
Publicado 2011
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1223“…Radiographs demonstrated multiple healing metaphyseal and rib fractures and bilateral femoral bowing. …”
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1224por Lips, Katrin Susanne, Kauschke, Vivien, Hartmann, Sonja, Thormann, Ulrich, Ray, Seemun, Kampschulte, Marian, Langheinrich, Alexander, Schumacher, Matthias, Gelinsky, Michael, Heinemann, Sascha, Hanke, Thomas, Kautz, Armin R., Schnabelrauch, Matthias, Schnettler, Reinhard, Heiss, Christian, Alt, Volker, Kilian, Olaf“…In addition, wedge-shaped defects of 3, 4, or 5 mm were generated in the distal metaphyseal area of femur via osteotomy. The 4 mm defects were subsequently used for implantation studies where bone substitution materials of calcium phosphate cement, composites of collagen and silica, and iron foams with interconnecting pores were inserted. …”
Publicado 2013
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1225por Harrasser, Norbert, Gorkotte, Johannes, Obermeier, Andreas, Feihl, Susanne, Straub, Melanie, Slotta-Huspenina, Julia, von Eisenhart-Rothe, Ruediger, Moser, Walter, Gruner, Philipp, de Wild, Michael, Gollwitzer, Hans, Burgkart, Rainer“…METHODS: We developed a metaphyseal rat model of peri-implant bone infection with low amount of bacterial loads (10(2) and 10(3) CFU of Staphylococcus aureus) and investigated osseointegration of the implants coated with hydroxyapatite (HA) and low-dosed HA-silver (HA-Ag). …”
Publicado 2016
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1226por Neumann, Mirjam V., Strohm, Peter C., Reising, Kilian, Zwingmann, Joern, Hammer, Thorsten O., Suedkamp, Norbert P.“…CONCLUSION: Plate fixation in distal metaphyseal fractures has a higher risk of problems related to wound healing and postoperative wound infections.…”
Publicado 2016
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1227por Haysom, Samuel S., Vickers, Mark H., Yu, Lennex H., Reynolds, Clare M., Firth, Elwyn C., McGlashan, Sue R.“…No abnormal features were detected in the hyaline articular cartilage or in the metaphyseal growth plate in all four groups. However, collagen type X- positive regions of retained epiphyseal growth cartilage (EGC) was present in all HF-fed animals and significantly greater than that observed in Chow-fed sedentary rats. …”
Publicado 2017
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1228por Li, Kuei-Chang, Chang, Yu-Han, Hsu, Mu-Nung, Lo, Shih-Chun, Li, Wan-Hua, Hu, Yu-Chen“…As a result, OVX-ASCs implantation into OVX rats failed to heal critical-size metaphyseal bone defects. We further engineered the OVX-ASCs with a novel Cre/loxP-based hybrid baculovirus vector that conferred prolonged expression of miR-214 sponge. …”
Publicado 2017
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1229por Liao, Mei-Hsiu, Lin, Pei-I, Ho, Wei-Pin, Chan, Wing P, Chen, Ta-Liang, Chen, Ruei-Ming“…This translational study was further designed to evaluate the roles of GATA-3 in regulating bone healing and to explore its possible mechanisms. A metaphyseal bone defect was created in the left femurs of male ICR mice. …”
Publicado 2017
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1230por Taddio, Andrea, Ferrara, Giovanna, Insalaco, Antonella, Pardeo, Manuela, Gregori, Massimo, Finetti, Martina, Pastore, Serena, Tommasini, Alberto, Ventura, Alessandro, Gattorno, Marco“…CNO predominantly affects metaphyses of long bones, but clavicle and mandible, even if rare localizations of the disease, are very consistent with CNO diagnosis. …”
Publicado 2017
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1231por Lingner, Manuel, Seidling, Roland, Lehmann, Lars Johannes, Mauermann, Eckhard, Obertacke, Udo, Schwarz, Markus Ludwig Rupert“…They received four dumbbell-shaped implants in the metaphyseal parts of the femora. The implants had a TPS surface with (CSA group) and without a CSA treatment (TPS group). …”
Publicado 2018
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1232por Bell, P. A., Dennis, E. P., Hartley, C. L., Jackson, R. M., Porter, A., Boot-Handford, R. P., Pirog, K. A., Briggs, M. D.“…MANF plays a cytoprotective role in several soft tissues and is upregulated in conditions resulting from intracellular retention of mutant protein, including two skeletal diseases, metaphyseal chondrodysplasia, Schmid type (MCDS) and multiple epiphyseal dysplasia (MED). …”
Publicado 2018
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1233por Barth, Johannes, Garret, Jérôme, Geais, Laurent, Bothorel, Hugo, Saffarini, Mo, Godenèche, Arnaud“…All stems shared identical head geometry and differed only in the proximal metaphyseal area. Finite element analyses were performed, with the humerus rigidly constrained distally, and loaded to simulate the joint reaction force. …”
Publicado 2019
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1234“…In method 4, the CPF was fixed through a dorsal approach between the comminuted metaphyseal fragments. RESULTS: With the exception of one patient with delayed union, all patients had achieved union at 3-month followup. …”
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1235por Vierkant, Tillmann, Deutschländer, Robert, Sinnott-Armstrong, Walter, Haynes, John-Dylan“…Semi-compatibilists insist that the metaphysical debate on the nature of free will can be separated from the debate on conditions of responsible agency. …”
Publicado 2019
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1236por Issa, Zaid, Rasmussen, Jeppe Vejlgaard, Petersen, John Kloth, Schantz, Kim, Brorson, Stig“…BACKGROUND: Stemless shoulder arthroplasty systems with uncemented metaphyseal fixation have been used for glenohumeral osteoarthritis since 2004 (Hawi, et al. …”
Publicado 2019
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1237“…Reduction of the fragment of the ulnar styloid was achieved using distal radioulnar joint arthroscopy. The metaphyseal and intra-articular fracture of the radius and the fragment of the ulnar styloid were fixed using a volar locking plate and tension band wiring technique, respectively. …”
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1238por Barratclough, Ashley, Sanz-Requena, Roberto, Marti-Bonmati, Luis, Schmitt, Todd L., Jensen, Eric, García-Párraga, Daniel“…The most informative areas to evaluate morphologically were the metaphyseal regions of the radius and ulna, and the proximal and distal epiphysis of metacarpals II and III. …”
Publicado 2019
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1239“…Primary total knee arthroplasty (TKA) may be of benefit in elderly patients with a combination of osteoporotic bone and metaphyseal comminution. However, there continues to be conflicting evidence on the use of TKA for primary treatment of tibial plateau fracture. …”
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1240por Baraka, Mostafa M., Hefny, Hany M., Thakeb, Mootaz F., Fayyad, Tamer A., Abdelazim, Haytham, Hefny, Mamdouh H., Mahran, Mahmoud A.“…Imhauser osteotomy is capable of realigning the deformity without the risk of ON, but the remaining metaphyseal bump is implicated with significant chondro-labral lesions and accelerated osteoarthritis. …”
Publicado 2020
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