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141por Jahan, Mst Sharifa, Tsuzuki, Takamasa, Ito, Takuji, Bhuiyan, Md. Eliusur Rahman, Takahashi, Ikuko, Takamatsu, Hyota, Kumanogoh, Atsushi, Negishi, Takayuki, Yukawa, Kazunori“…PV cells were found to express molecule interacting with CasL 1 (MICAL1), an effector involved in Sema-Plxn signaling for axon guidance, suggesting MICAL1 and PlxnA1 co-expression in PV cells. …”
Publicado 2022
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142Publicado 1992Tabla de Contenidos: “…Romanyshyn -- Making the unknown known: art as the speech of the body / Mical Goldfarb -- The wider role of bodily sense in thought and language / Eugene T. …”
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143por Bron, Romke, Vermeren, Matthieu, Kokot, Natalie, Andrews, William, Little, Graham E, Mitchell, Kevin J, Cohen, James“…Finally, knockdown of MICAL3, a downstream semaphorin/Plexin-A signalling molecule, in chick motor neurons led to their ectopic positioning in the PNS. …”
Publicado 2007
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144“…Five DELs could interact with 11 DEMs to regulate 242 DEGs, which was used to construct the ceRNA network, including TMEM51-AS1-miR-106b-SNX21/ TRAPPC10, LINC00324/RUSC1-AS1-miR-16-SPRY4/MICAL2/ SLC39A14, RUSC1-AS1-miR-10-SCG5 and RUSC1-AS1-miR-7-ZFP1 ceRNAs axes. …”
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145“…We have found that a new actin regulatory enzyme Mical is poorly soluble when expressed in bacteria but the use of a Nus fusion protein tag greatly increases its solubility. …”
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146por Rai, Amrita, Oprisko, Anastasia, Campos, Jeremy, Fu, Yangxue, Friese, Timon, Itzen, Aymelt, Goody, Roger S, Gazdag, Emerich Mihai, Müller, Matthias P“…In this study, we have thoroughly characterized a Rab effector domain that is present in proteins of the Mical and EHBP families, both known to act in endosomal trafficking. …”
Publicado 2016
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147“…Thus detection of non-Gaussian correlations in the CMB of one of these bispectral shape functions can both pinpoint the origins of primordial density fluctuations, and distinguish between different dyna mical models of cosmological vacuum dark energy…”
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148por Ioannou, Maria S., Bell, Emily S., Girard, Martine, Chaineau, Mathilde, Hamlin, Jason N.R., Daubaras, Mark, Monast, Anie, Park, Morag, Hodgson, Louis, McPherson, Peter S.“…DENND2B interacts with the Rab13 effector MICAL-L2 at the cell periphery, and this interaction is required for the dynamic remodeling of the cell’s leading edge. …”
Publicado 2015
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149por Dumas, Audrey, Lê-Bury, Gabrielle, Marie-Anaïs, Florence, Herit, Floriane, Mazzolini, Julie, Guilbert, Thomas, Bourdoncle, Pierre, Russell, David G., Benichou, Serge, Zahraoui, Ahmed, Niedergang, Florence“…We showed that maturation arrest occurred at the level of the EHD3/MICAL-L1 endosomal sorting machinery. Unexpectedly, we found that the regulatory viral protein (Vpr) was crucial to perturb phagosome maturation. …”
Publicado 2015
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150“…Sema2b-PlexB signaling regulates the expression of PHP via the cytoplasmic protein Mical and the oxoreductase-dependent control of presynaptic actin(6,7). …”
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151“…We observed interactions and colocalization between Bcl-xL, VPS35, VPS26, and MICAL-L1, a protein involved in recycling endosome biogenesis that also interacts with the retromer. …”
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152por Maemoto, Yuki, Maruyama, Tomohiro, Nemoto, Kazuaki, Baba, Takashi, Motohashi, Manae, Ito, Akihiro, Tagaya, Mitsuo, Tani, Katsuko“…Depletion of DDHD1 caused enlargement of early endosomes and stimulated tubulation of recycling endosomes positive for phosphatidic acid-binding proteins syndapin2 and MICAL-L1. Knockout of DDHD1 enhanced transferrin recycling from recycling endosomes to the cell surface. …”
Publicado 2020
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153por Yang, Yanda, Chang, Chencheng, Baiyin, Batu, Liu, Zaixia, Guo, Lili, Zhou, Le, Liu, Bin, Shi, Caixia, Zhang, Wenguang“…Combing with Exon Wide Selection Signature (EWSS) and protein-protein interaction (PPI) analysis revealed that TPCN2, KIF22, MICAL3, RUNX2, PDE4A, TESK2, GPM6A, POLR1A, and KLHL6 involved in early growth and postpartum diseases. …”
Publicado 2022
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154“…As a proof of concept, we investigated in detail the binding interfaces of two protein assemblies: the complex formed by MICAL3, ELKS and Rab8A, which is involved in exocytosis, and the complex of SLAIN2, CLASP2 and ch-TOG, which controls microtubule dynamics. …”
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155“…Additional results from the METABRIC datasets showed that ORN could characterize critical mechanisms of cancer and connect them to less studied somatic mutations (e.g., BAP1, MIR604, MICAL3, and telomere activities), which may generate novel hypothesis for targeted therapy.…”
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156por Wong, Jack Jing Lin, Li, Song, Lim, Edwin Kok Hao, Wang, Yan, Wang, Cheng, Zhang, Heng, Kirilly, Daniel, Wu, Chunlai, Liou, Yih-Cherng, Wang, Hongyan, Yu, Fengwei“…The SCF E3 ligase consists of four core components Cullin1/Roc1a/SkpA/Slimb and promotes ddaC dendrite pruning downstream of EcR-B1 and Sox14, but independently of Mical. Moreover, we demonstrate that the Cullin1-based E3 ligase facilitates ddaC dendrite pruning primarily through inactivation of the InR/PI3K/TOR pathway. …”
Publicado 2013
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157“…We show that in the absence of Rab8 family members, the C-terminal bivalent Mical/EHBP Rab binding (bMERB) domain forms an intramolecular complex with its central calponin homology (CH) domain and auto-inhibits actin binding. …”
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158“…Moreover, we demonstrate that at least 3 different asparagine-proline-phenylalanine (NPF) motif-containing EHD binding partners, Rabenosyn-5, Syndapin2 and MICAL-L1, are required for the recruitment of EHD1 to SE. …”
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159por Tsai, Feng-Chun, Chen, Yu-Lin, Yen, Kun-Chi, Chiu, Cheng-Hsun, Chen, Jui-Hsuan, Yeh, Yung-Hsin, Tsai, Pei-Chien“…Using cutoff values at the 1% FDR significance level and sex- and age-adjusted regression models, we identified 12 significant DEGs (CTGF, MAP1B, SERPINE1, MYH9, MICAL2, MYO1D, CRY1, AQP7P3, HTRA1, PRSS23, IGFBP2, and FN1). …”
Publicado 2021
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160por Boddy, Kirsten C., Zhu, Hongxian, D’Costa, Vanessa M., Xu, Caishuang, Beyrakhova, Ksenia, Cygler, Miroslaw, Grinstein, Sergio, Coyaud, Etienne, Laurent, Estelle M. N., St-Germain, Jonathan, Raught, Brian, Brumell, John H.“…During infection, Rab10 and its effectors MICAL-L1 and EHBP1 are recruited to invasion sites. …”
Publicado 2021
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