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161por Ho, Joel R., Chapeaublanc, Elodie, Kirkwood, Lisa, Nicolle, Remy, Benhamou, Simone, Lebret, Thierry, Allory, Yves, Southgate, Jennifer, Radvanyi, François, Goud, Bruno“…Five of these deregulated genes (LEPRE1, MICAL2, RAB23, STXBP1, SYTL1) were specifically deregulated in FGFR3-non-mutated muscle-invasive tumors. …”
Publicado 2012
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162“…Indeed, the EHD1 RPF motif was required for dimerization, interaction with MICAL-L1 and Syndapin2, as well as localization to tubular recycling endosomes. …”
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163por Belone, Andrea de Faria F., Rosa, Patrícia S., Trombone, Ana P. F., Fachin, Luciana R. V., Guidella, Cássio C., Ura, Somei, Barreto, Jaison A., Pinilla, Mabel G., de Carvalho, Alex F., Carraro, Dirce M., Soares, Fernando A., Soares, Cleverson T.“…Some of these genes were observed in all forms of the disease (CD2, CD27, chit1, FA2H, FAM26F, GZMB, MMP9, SLAMF7, UBD) and others were exclusive to reactional forms (Type “1” reaction: GPNMB, IL1B, MICAL2, FOXQ1; Type “2” reaction: AKR1B10, FAM180B, FOXQ1, NNMT, NR1D1, PTX3, TNFRSF25). …”
Publicado 2015
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164por Grauzam, Stéphane, Brock, Amanda M., Holmes, Casey O., Tiedeken, Jessica A., Boniface, Samantha G., Pierson, Bailey N., Patterson, Daniel G., Coaxum, Sonya D., Neskey, David M., Rosenzweig, Steven A.“…E13NEDD9 expression blocked MMP9 secretion and invadopodia formation. MICAL1 (molecule interacting with Cas-L1) silencing with a short hairpin RNA reduced MMP9 secretion, vimentin and E-cadherin levels while increasing N-cadherin and Rab6 levels, consistent with reduced invasive behavior. …”
Publicado 2018
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165por Jiang, Yanan, Sun, Huimeng, Xu, Hong, Hu, Xin, Wu, Wenqi, Lv, Yangyang, Wang, Jinhuan, Liu, Su, Zhai, Yixin, Tian, Linyan, Wang, Yafei, Zhao, Zhigang“…By a least absolute shrinkage and selection operator (LASSO)-Cox regression model, a sixteen-gene risk signature, comprising ANTXR1, CD3D, TIMP1, FPR3, NID2, CTLA4, LPAR6, GPR183, LYZ, PTGDS, ITK, FBN1, FRMD6, PLAU, MICAL2, C1S, was established. The comprehensive results showed that the high-risk group was correlated with lower immune infiltration, more aggressive phenotypes, lower overall survival and more sensitive to lenalidomide. …”
Publicado 2022
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166por Bayer, Michael, Fischer, Julia, Kremerskothen, Joachim, Ossendorf, Edith, Matanis, Theodoros, Konczal, Magdalena, Weide, Thomas, Barnekow, Angelika“…To date p115, GM130, golgin-84 and MICAL have been identified as direct interacting partners. …”
Publicado 2005
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167por Hook, Sharon C., Chadt, Alexandra, Heesom, Kate J., Kishida, Shosei, Al-Hasani, Hadi, Tavaré, Jeremy M., Thomas, Elaine C.“…Using an unbiased quantitative proteomics approach, we identified proteins that interact with TBC1D1 in C2C12 myotubes including VPS13A and VPS13C, the Rab binding proteins EHBP1L1 and MICAL1, and the calcium pump SERCA1. These proteins associate with TBC1D1 via its phosphotyrosine binding (PTB) domains and their interactions with TBC1D1 were unaffected by AMPK activation, distinguishing them from the AMPK regulated interaction between TBC1D1 and AMPKα1 complexes. …”
Publicado 2020
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168“…RESULTS: The B cells closely related module was identified, and five genes, including ARID5A, CLEC2B, MICAL1, MZB1, and RAPGEF1, were ultimately selected to establish a prognostic signature to calculate the risk scores of PAAD patients. …”
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169Pleiotropic Genes for Pulmonary Function and Aging-Related Traits: The Long Life Family Study (LLFS)por Feitosa, Mary, Wojczynski, Mary, Anema, Jason, Daw, E Warwick, Wang, Lihua, Nygaard, Marianne, Santanasto, Adam, Province, Michael“…We identified pleiotropic loci for FEV1 (or FVC), IL-6 and hsCRP within CYCS, CALN1, TRIM9, AXIN2, MICAL3, and CMIP; FEV1 (or FVC) and BMI within CYP2U1, LINC00871-RPL10L-MDGA2, and LOC105372472; FEV1 (or FVC) and grip strength within XXYLT1 and MAL2; FEV1 and FPG within MAF; and FVC and HbA1c within HDHD3. …”
Publicado 2021
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170por Fang, Ke‐Ying, Liang, Gui‐Ning, Zhuang, Zhuo‐Qing, Fang, Yong‐Xin, Dong, Yu‐Qian, Liang, Chuang‐Jia, Chen, Xin‐Yan, Guo, Xu‐Guang“…RESULTS: In this study, 6622 differentially expressed genes were identified in the group CR, among which RAB11B‐AS1, DISP1, MICAL3, PSMG1, and DOCK4 were up‐regulated genes, and ANAPC1, IGLV1‐40, SORT1, PLPPR2, and ATP1A1‐AS1 were down‐regulated. 7335 genes were screened in the group HR, including the top 5 up‐regulated genes ALKBH6, AMBRA1, MIR1249, TRAV18, and LRRC69, and the top 5 down‐regulated genes FAM241B, AC018529.3, AL031963.3, AC006946.1, and FAM149B1. …”
Publicado 2022
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171por Bu, Shufeng, Lau, Samuel Song Yuan, Yong, Wei Lin, Zhang, Heng, Thiagarajan, Sasinthiran, Bashirullah, Arash, Yu, Fengwei“…Knockdown of the core PRC1 component Polyhomeotic (Ph) or Abd-B overexpression selectively downregulates Mical expression, thereby inhibiting ecdysone signalling. …”
Publicado 2023
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172por Sun, Yi, Huang, Shuna, Wan, Chunyu, Ruan, Qishuang, Xie, Xiaoxu, Wei, Donghong, Li, Guobo, Lin, Shaowei, Li, Huangyuan, Wu, Siying“…Conversely, lnc-MICALL2-2 inhibition in vitro attenuated the effects of oxLDL on HCAECs morphology, proliferation, and apoptosis. …”
Publicado 2021
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