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  1. 2021
    “…Most of the participants were older (> 65 years old) and the perspectives of middle-aged people were largely absent. Factors impacting on future housing decisions among individuals were identified. …”
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    Middle aged and older adult’s perspectives of their own home environment: a review of qualitative studies and meta-synthesis
  2. 2022
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    Endovascular treatment of Takayasu arteritis in a middle-aged woman with syncope and limb claudication: a case report
  3. 2023
    “…Therefore, we comprehensively examined the association of sedentary time with overall CVD risk and various metabolic risk factors in T2DM patients. A total of 775 middle-aged and elderly patients with T2DM were assessed. …”
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    The effect of sedentary time on cardiovascular disease risk in middle-aged and elderly patients with type 2 diabetes mellitus
  4. 2024
    “…This study will recruit middle-aged participants with an older DNA methylation age compared to their chronological age, and test whether supplementation with Ca-AKG can reduce DNA methylation age. …”
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    Alpha-ketoglutarate supplementation and BiologicaL agE in middle-aged adults (ABLE)—intervention study protocol
  5. 2025
    “…We aimed to examine the effects of pre-exercise high and low GI meals on substrate oxidation and food reward in middle-aged Japanese women. This randomised crossover trial included fifteen middle-aged women (aged 40⋅9 ± 6⋅5 years, mean ± sd). …”
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    Effects of pre-exercise high and low glycaemic index meals on substrate metabolism and appetite in middle-aged women
  6. 2026
    “…CONCLUSIONS: Sleep disorders including insomnia, poor sleep quality, and short and long sleep duration were significantly associated with physical frailty among middle-aged and older PWH. Depression may play a mediating role in the sleep–frailty association.…”
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    Association of Insomnia, Sleep Quality, and Sleep Duration With Risk of Physical Frailty in Middle-aged and Older People With HIV
  7. 2027
    “…METHODS: The SOC scores of 138 pairs of middle-aged women and their children (junior high school students) were compared at two time points: 2019 (before the pandemic, T1) and 2020 (during the pandemic, T2). …”
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    Transitions in sense of coherence among middle-aged women raising adolescents before and during the COVID-19 pandemic
  8. 2028
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    Relationship of blood and bone lead to menopause and bone mineral density among middle-age women in Mexico City.
  9. 2029
    “…CONCLUSION: These findings suggest that middle-aged obese adults may already be experiencing differentially greater brain atrophy, and may potentially be at greater risk for future cognitive decline.…”
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    The effect of body mass index on global brain volume in middle-aged adults: a cross sectional study
  10. 2030
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    Who is maintaining weight in a middle-aged population in Sweden? A longitudinal analysis over 10 years
  11. 2031
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    Vasectomy, cigarette smoking, and age at first sexual intercourse as risk factors for prostate cancer in middle-aged men.
  12. 2032
    “…CONCLUSION: The 2-year intervention up-regulated mitochondrial HSP expressions in middle-aged subjects with impaired glucose tolerance. …”
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    Exercise training with dietary counselling increases mitochondrial chaperone expression in middle-aged subjects with impaired glucose tolerance
  13. 2033
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    Salt and salted food intake and subsequent risk of gastric cancer among middle-aged Japanese men and women
  14. 2034
    “…BACKGROUND: Public health research characterising the course of life through the middle age in developing societies is scarce. The aim of this study is to explore patterns of adult (15–64 years) mortality in an Ethiopian population over time, by gender, urban or rural lifestyle, causes of death and in relation to household economic status and decision-making. …”
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    Young adult and middle age mortality in Butajira demographic surveillance site, Ethiopia: lifestyle, gender and household economy
  15. 2035
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    Aorta of young and middle-aged heterozygous familial hypercholesterolemia patients shows no functional or morphological impairment assessed by MRI
  16. 2036
    “…We examined whether the metabolic syndrome is associated with the onset of depressive symptoms in a cohort of middle-aged British civil servants. RESEARCH DESIGN AND METHODS—Analyses included 5,232 participants (41–61 years of age) from the Whitehall II prospective cohort study. …”
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    Association Between Metabolic Syndrome and Depressive Symptoms in Middle-Aged Adults: Results from the Whitehall II study
  17. 2037
    “…This study assessed current levels of penicilin resistance among Streptococcus Pneumoniae causing pneumonia in Spanish middle age and older adults. METHODS: Antimicrobial susceptibility was tested for 104 consecutive isolates of Streptococcus pneumoniae recovered from patients 50 years or older with radiographically confirmed pneumonia in the region of Tarragona (Spain) between 2002 and 2007. …”
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    Drug-resistance in Streptococcus pneumoniae isolates among Spanish middle aged and older adults with community-acquired pneumonia
  18. 2038
    “…CONCLUSION: Levels of good sleep quality in middle-age and elderly Chinese were low. Gender, geographical location, self-rated health, depression and sleep quantity were major factors associated with sleep quality. …”
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    Sleep quality in middle-aged and elderly Chinese: distribution, associated factors and associations with cardio-metabolic risk factors
  19. 2039
    “…CONCLUSION: Only one third of middle-aged and elderly Chinese assessed their health status as good or very good. …”
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    Self-Rated Health in middle-aged and elderly Chinese: distribution, determinants and associations with cardio-metabolic risk factors
  20. 2040
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    Distribution of the Ankle-Brachial Index and Associated Cardiovascular Risk Factors in a Population of Middle-Aged and Elderly Koreans
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