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  1. 2501
    “…However, the precise role of TonEBP in the middle-aged brain is not yet known. We used TonEBP haploinsufficient mice to investigate the role of TonEBP in middle-aged or amyloid β oligomer (AβO)–injected brains and examined the effect of TonEBP knockdown on AβO-treated BV2 microglial cells. …”
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    TonEBP Haploinsufficiency Attenuates Microglial Activation and Memory Deficits in Middle-Aged and Amyloid β Oligomer-Treated Mice
  2. 2502
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    Greater medial proximal tibial slope is associated with bone marrow lesions in middle-aged women with early knee osteoarthritis
  3. 2503
    “…The meta-analysis found that BP was associated with higher odds of all-cause dementia in middle-aged and older participants in both cohort studies(HR = 1.41,95% CI: 1.20–1.66, P = 0.000) and case-control (OR = 4.25, 95% CI, 2.73–6.61; P = 0.000). …”
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    The association between bullous pemphigoid and cognitive outcomes in middle-aged and older adults: A systematic review and meta-analysis
  4. 2504
    “…The outcome was response to a postal questionnaire sent (2001–2003) to surviving cohort members in middle age. RESULTS: Of 11,282 potentially mailed subjects, 7,183 (63.7%) returned questionnaires. …”
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    Early life factors, childhood cognition and postal questionnaire response rate in middle age: the Aberdeen Children of the 1950s study
  5. 2505
    “…We studied the influence of bone resorption rate on the release of lead from bone in 333 men, predominantly white, middle-aged and elderly (mostly retired) from the Boston area. …”
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    Influence of bone resorption on the mobilization of lead from bone among middle-aged and elderly men: the Normative Aging Study.
  6. 2506
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    Differences in Tumor-Associated Protein Levels among Middle-Age Flemish Women in Association with Area of Residence and Exposure to Pollutants
  7. 2507
    “…In this investigation we examined the interrelationships of lead levels in whole blood corrected by hematocrit [i.e., erythrocyte lead (EPb)], trabecular bone (TBoPb), cortical bone (CBoPb), and urine excreted over 24 hr (UPb); all samples were obtained from 71 middle-aged and elderly men with no known occupational lead exposures. …”
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    The independent contribution of bone and erythrocyte lead to urinary lead among middle-aged and elderly men: the normative aging study.
  8. 2508
    “…No change in incidence over time was observed for men. In older and middle-aged women there was however a statistically significant increase. …”
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    Rising incidence of pancreatic carcinoma in middle-aged and older women-time trends 1961-90 in the city of Malmö, Sweden.
  9. 2509
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    APOE status and its association to learning and memory performance in middle aged and older Norwegians seeking assessment for memory deficits
  10. 2510
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    COX-2 Gene Promoter Polymorphism and Coronary Artery Disease in Middle-Aged Men: The Helsinki Sudden Death Study
  11. 2511
    “…BACKGROUND: The association between socioeconomic position in middle age and risk of subsequent, short-term weight gain is unknown. …”
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    Socioeconomic position and risk of short-term weight gain: Prospective study of 14,619 middle-aged men and women
  12. 2512
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    Social inequalities in self-rated health by age: Cross-sectional study of 22 457 middle-aged men and women
  13. 2513
    “…To examine these associations, 101 middle-aged adults were recruited, completed a battery of psychological questionnaires and were administered a battery of cognitive tasks that assess frontal lobe and hippocampal function. …”
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    Polymorphism of the 5-HT(2A) Receptor Gene: Association with Stress-Related Indices in Healthy Middle-Aged Adults
  14. 2514
    “…Our aim was to investigate relationships between retirement and 3-year changes in leisure-time physical activity (LTPA) patterns and sedentary behaviour in middle-aged French adults. METHODS: Past-year LTPA and sedentary behaviour (watching television) were assessed in 1998 and 2001 using the Modifiable Activity Questionnaire on participants in the SU.VI.MAX (Supplementation with Antioxidants and Minerals) study. …”
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    Changes in leisure-time physical activity and sedentary behaviour at retirement: a prospective study in middle-aged French subjects
  15. 2515
    “…Total of 2,761 young and middle aged adults (574 aged 19~29 years and 2,187 aged 30~49 years) were selected from KNHANES III. …”
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    Relationship between dietary sodium, potassium, and calcium, anthropometric indexes, and blood pressure in young and middle aged Korean adults
  16. 2516
    por Deeg, Dorly J. H., Huisman, Martijn
    Publicado 2010
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    Cohort differences in 3-year adaptation to health problems among Dutch middle-aged, 1992–1995 and 2002–2005
  17. 2517
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    Opposite Associations of Trunk and Leg Fat Depots with Plasma Ferritin Levels in Middle-Aged and Older Chinese Men and Women
  18. 2518
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    Lessons from Studies in Middle-Aged and Older Adults Living in Mediterranean Islands: The Role of Dietary Habits and Nutrition Services
  19. 2519
    por Luncheon, Cecily, Zack, Matthew
    Publicado 2011
    “…CONCLUSION: Future studies should try to confirm if and clarify why the association between physical activity level and health-related quality of life differs among these middle-aged women of different races/ethnicities. If confirmed, this association would imply that health care professionals and those who design public health interventions may need to vary their promotion methods and messages to encourage physical activity among women of different races/ethnicities.…”
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    Health-Related Quality of Life and the Physical Activity Levels of Middle-Aged Women, California Health Interview Survey, 2005
  20. 2520
    “…Responding middle-aged rats displayed a reduction of ER-β mRNA in the preoptic area which was similar to the effect in young rats. …”
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    Expression of estrogen receptors in the hypothalamo-pituitary-ovarian axis in middle-aged rats after re-instatement of estrus cyclicity
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