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  1. 2961
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    Measures of MRI Brain Biomarkers in Middle Age According to Average Modified Mediterranean Diet Scores Throughout Young and Middle Adulthood
  2. 2962
    “…BACKGROUND: Fracture risks and associated factors are poorly understood in middle-aged and older Asian populations with inflammatory bowel disease (IBD). …”
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    Fracture Risk in Middle-Aged and Older Patients With Inflammatory Bowel Disease: A Korean Nationwide Population-Based Cohort Study
  3. 2963
    “…This study investigates whether a computer-based speechreading training improves audiovisual speech perception in noise in a sample of middle-aged and older adults (N = 62, 47–83 years) with 32 participants completing a speechreading training and 30 participants of an active control group completing a foreign language training. …”
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    Improvements in naturalistic speech-in-noise comprehension in middle-aged and older adults after 3 weeks of computer-based speechreading training
  4. 2964
    por Du, Xiwang, Liao, Jiazhi, Ye, Qing, Wu, Hong
    Publicado 2023
    “…BACKGROUND: There is growing evidence that the internet has beneficial effects on the mental health of middle-aged and older people (≥45 years), but the evidence is inconclusive, and the underlying mechanisms are less known. …”
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    Multidimensional Internet Use, Social Participation, and Depression Among Middle-Aged and Elderly Chinese Individuals: Nationwide Cross-Sectional Study
  5. 2965
    “…Therefore, the present study aimed at investigating whether serum UA (sUA) is associated with cognitive performance in healthy middle-aged individuals. We conducted a cross-sectional study on a cohort of middle-aged individuals (40–60 years old) who participated in the Qatar Biobank. …”
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    Higher serum uric acid is associated with poorer cognitive performance in healthy middle-aged people: a cross-sectional study
  6. 2966
    por Hou, Bo, Qiu, Jiang
    Publicado 2023
    “…This study aimed to evaluate the association between bone metabolism indices and glycated hemoglobin (HbA1c) levels in middle-aged and older adult patients with type 2 diabetes mellitus (T2DM). …”
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    Correlation analysis of bone metabolism indices and glycosylated hemoglobin in middle-aged and older adult patients with type 2 diabetes mellitus
  7. 2967
    “…This randomized controlled trial aimed to investigate the effects of eight weeks of lactotripeptide (LTP) ingestion, physical activity (PA) intervention, and combined intervention on the fatigue status of middle-aged and older adults. A total of 78 middle-aged and older adults (63 ± 8 years of age) were randomly assigned to four groups: placebo, LTP, placebo with PA intervention (placebo + PA), and LTP with PA intervention (LTP + PA). …”
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    Effects of lactotripeptide ingestion and physical activity intervention on the fatigue status of middle-aged and older adults: a randomized controlled trial
  8. 2968
    “…This study aimed to examine the associations between hyperuricemia and different anthropometric indices in middle-aged and older male patients with T2DM. METHODS: In this retrospective study, a total of 1447 middle-aged (45—65 years, n = 791) and older (≥ 65 years, n = 656) male patients with T2DM were collected from December 2015 to January 2020 at Shanghai Xinhua Hospital. …”
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    Hip circumference has independent association with the risk of hyperuricemia in middle-aged but not in older male patients with type 2 diabetes mellitus
  9. 2969
    “…Higher adherence to the AMED, DASH, and CHFP dietary patterns was inversely associated with poor cognition in Chinese middle-aged and elderly adults, particularly among urban residents.…”
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    Higher Adherence to the AMED, DASH, and CHFP Dietary Patterns Is Associated with Better Cognition among Chinese Middle-Aged and Elderly Adults
  10. 2970
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    Longitudinal trajectories of memory among middle-aged and older people with hearing loss: the influence of cochlear implant use on cognitive functioning
  11. 2971
    “…Studies have exhibited that middle-aged adults approaching the transition to an older state show more pronounced DA than the more senior. …”
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    Mediating effect of successful aging on the relationship between psychological resilience and death anxiety among middle-aged and older adults with hypertension
  12. 2972
    “…BACKGROUND: Oral lichen planus (OLP) is an autoimmune disease primarily affecting the middle-aged females. The present study aims to determine the relation of the oestrogen receptor alpha (ERα) with OLP pathogenesis, correlating it with the possible cause of its higher prevalence among females. …”
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    Expression of Oestrogen Receptor Alpha (ERα) in Oral Lichen Planus – A Precancerous Inflammatory Disease in Middle-Aged Females
  13. 2973
    “…This systematic review summarizes the effect of social integration or social connectedness interventions among young- and middle-aged cancer patients and survivors based on 28 empirical studies published between 2000 and 2021. …”
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    Interventions with Social Integration Components Addressing Psychosocial Outcomes of Young- and Middle-Aged Adult Cancer Individuals: A Systematic Review
  14. 2974
    “…We assessed the prevalence of depressive symptoms and their association with age, chronic conditions, and health status among middle-aged and elderly people in peri-urban Dar es Salaam, Tanzania. …”
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    Depressive symptoms and their association with age, chronic conditions and health status among middle-aged and elderly people in peri-urban Tanzania
  15. 2975
    “…The young schizophrenia patients had higher risk of suicidality than middle-aged and elderly schizophrenia patients (P = 0.001). …”
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    Visuospatial ability and attention as risk factors for suicidal ideation in middle-aged and elderly schizophrenia patients: a cross-sectional study
  16. 2976
    “…However, to date, no reviews have investigated the role of siblings in assisting their middle-aged and older brothers or sisters with SMI as they age within community settings. …”
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    Protocol for a scoping review of the role of siblings in supporting middle-aged and older people with early-acquired severe mental illness
  17. 2977
    “…In this study, we aimed to assess the therapeutic potential of CBD among middle-aged female rats exposed to social isolation (SI) and the potential involvement of brain-derived neurotrophic factor (BDNF) in these effects. …”
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    Cannabidiol Modulates Emotional Function and Brain-Derived Neurotrophic Factor Expression in Middle-Aged Female Rats Exposed to Social Isolation
  18. 2978
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    The Impact of Sedentary Behavior on Renal Function Decline in 132,123 Middle Aged and Older Adults: A Nationwide Cohort Study
  19. 2979
    “…This study aims to explore the correlation between depression and BPH among middle-aged and older men in India. METHODS: We utilized data from male individuals aged 45 years and older who participated in the initial wave (2017–2018) of the Longitudinal Aging Study in India (LASI). …”
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    The relationship between depression and benign prostatic hyperplasia in middle-aged and elderly men in India: a large-scale population study
  20. 2980
    “…This study included middle-aged women residing in older adults’ welfare facilities in G-gu, Busan, from May to August 2021. …”
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    Effect of Individual Virtual Reality Cognitive Training Programs on Cognitive Function and Depression in Middle-Aged Women: Randomized Controlled Trial
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