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  1. 3341
    “…PURPOSE: To determine whether the APOE-ε4 allele modulates the relationship between regional β-amyloid (Aβ) accumulation and cognitive change in middle-aged cognitively unimpaired (CU) participants. …”
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    APOE-ε4 modulates the association between regional amyloid deposition and cognitive performance in cognitively unimpaired middle-aged individuals
  2. 3342
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    FULMINANT MYOCARDITIS IN A MIDDLE-AGED WOMAN WITH ULCERATIVE COLITIS AND RECENT EXPOSURE TO COVID-19 REQUIRING ORTHOTOPIC HEART TRANSPLANT
  3. 3343
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    Schwannoma-like uterine leiomyoma with fever of unknown origin and surgical management in a middle-aged woman: A case report
  4. 3344
    Libro
    Handbook of European history, 1400-1600 : late Middle Ages, Renaissance, and Reformation /
  5. 3345
    por Nesham, D B
    Publicado 1969
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    The challenge of change to the adult trainee: a study of labour turnover during and following trianing of middle-aged men and women for new skills
  6. 3346
    por Oh, Du-Hwan, Lee, Jang-Kyu
    Publicado 2023
    “…We aimed to investigate the effect of different intensities of aerobic exercise (VO(2)max: 50% vs. 80%) on body weight, body fat percentage, lipid profiles, and adipokines in obese middle-aged women after 8 weeks of combined aerobic and resistance exercise. …”
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    Effect of Different Intensities of Aerobic Exercise Combined with Resistance Exercise on Body Fat, Lipid Profiles, and Adipokines in Middle-Aged Women with Obesity
  7. 3347
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    Corrigendum: The association between diet and cardio-metabolic risk on cognitive performance: A cross-sectional study of middle-aged Australian adults
  8. 3348
    “…CONCLUSIONS: The high prevalence of multimorbidity in middle-aged adults in SSA is of concern, with women currently at higher risk. …”
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    Identifying the prevalence and correlates of multimorbidity in middle-aged men and women: a cross-sectional population-based study in four African countries
  9. 3349
    “…Objective: The study aimed to examine the dose–response associations between night-sleep duration and depression risk in middle-aged and older adults. Methods: We searched PubMed, Embase, Web of Science, CNKI, VIP, and the Wanfang data knowledge service platforms from inception to 31 July 2022. …”
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    Relationship between night-sleep duration and risk for depression among middle-aged and older people: A dose–response meta-analysis
  10. 3350
    “…BACKGROUND AND OBJECTIVE: Maintaining the life satisfaction of frail middle-aged and older adults when they experience physical disability, lower activity status, or complex conditions that are related to each other is now an urgent issue. …”
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    The effect of research on life satisfaction in middle-aged and older adults: physical disability and physical activity as a parallel and serial mediation analysis
  11. 3351
    “…Objective: To systematically evaluate the effect of low intensity resistance training with blood flow restriction on fall resistance in middle-aged and older adults. Methods: PubMed, The Cochrane Library, Web of Science, Embase, EBSCO host, CNKI Database, VIP, Wanfang Database and CBMdisc were searched, and the retrieval period was from the beginning of each database to 25 July 2022. …”
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    The Effect of Low Intensity Resistance Training with Blood Flow Restriction on Fall Resistance in Middle-Aged and Older Adults: A Meta-Analysis
  12. 3352
    “…Therefore, the purpose of the current study was to compare the effects of 12 weeks of CT and combined training on the aforementioned markers in overweight and obese males. Methods: Sixty middle-aged overweight and obese males (age 51 ± 4 years) were randomly assigned into one of four groups: endurance followed by resistance training (ER; n = 15), resistance followed by endurance training (RE; n = 15), combined resistance and endurance training (COM), or control (CON; n = 15). …”
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    The Effects of 12 Weeks of Concurrent and Combined Training on Inflammatory Markers, Muscular Performance, and Body Composition in Middle-Aged Overweight and Obese Males
  13. 3353
    “…CONCLUSION: Adversity experienced in childhood can affect the health status of middle-aged and older people. By ensuring adequate sleep and improving life satisfaction, health outcomes can be improved, and the negative effects of childhood adversity can be reduced.…”
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    Adverse childhood experiences affect the health of middle-aged and older people in China: The multiple mediating roles of sleep duration and life satisfaction
  14. 3354
    “…A total of 2,151,597 middle-aged subjects (between 50 and 59 years old) were enrolled. …”
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    The association between metabolic syndrome and heart failure in middle-aged male and female: Korean population-based study of 2 million individuals
  15. 3355
    por Yegla, Brittney, Rani, Asha, Kumar, Ashok
    Publicado 2023
    “…Middle-aged (~12 mo) male Fischer-344 rats were injected bilaterally in the medial prefrontal cortex (mPFC) with viral vector (LV), SR (LV-SR) or control (LV-GFP). …”
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    Viral vector-mediated upregulation of serine racemase expression in medial prefrontal cortex improves learning and synaptic function in middle age rats
  16. 3356
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    Echocardiography E/A Abnormality is Associated with the Development of Primary Left Ventricle Remodeling in Middle-Aged and Elderly Women: A Longitudinal Study
  17. 3357
    “…We are presenting a rare case of IMT in the bladder in a middle-aged man treated by partial cystectomy. A 62-year-old man consulted a urologist because of haematuria and dysuric disturbances. …”
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    Inflammatory Myofibroblastic Tumour of the Urinary Bladder in a Middle-Aged Man—A Case Report of an Unusual Localization of a Rare Tumour
  18. 3358
    “…Since some studies have shown an increase in senescent cells during aging, obesity, and neurodegenerative diseases, we proposed that cellular senescence participation may contribute to the cognitive decline in an obesity model of middle-aged female Wistar rats. The inflammatory state of 6 and 13 months-old female Wistar rats fed with a hypercaloric diet was measured in serum and CNS (cortex and hippocampus). …”
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    Chronic consumption of a hypercaloric diet increases neuroinflammation and brain senescence, promoting cognitive decline in middle-aged female Wistar rats
  19. 3359
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    Delusions, Hallucinations, and Cognitive Decline in Middle Age: A Case of Dementia, GIGYF2 Gene Mutation, and 22q11 Duplication
  20. 3360
    “…DISCUSSION AND IMPLICATIONS: Small reductions in SB and increments in MVPA were associated with higher cognitive function in middle-aged and older adults.…”
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    Association Between 24-Hour Movement Behavior and Cognitive Function in Brazilian Middle-Aged and Older Adults: Findings From the ELSA-Brasil
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